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Developing new tools to accelerate spatial genomics and drug discovery

We speak to Dr. George Emanuel from Vizgen about their new MERSCOPE Platform and how it is accelerating the field of drug discovery by combining both single-cell and spatial genomics.

From Vizgen 10 Jan 2023

NIH awards eight research grants to advance diagnosis of Multisystem Inflammatory Syndrome in Children

The National Institutes of Health has awarded eight research grants to refine new technologies for early diagnosis of severe illnesses resulting from SARS-CoV-2 infection in children.

9 Jan 2023

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Announcing a new article publication for Zoonoses journal. This study was aimed at screening differentially expressed genes (DEGs) and exploring the potential immune mechanism induced by the Bacillus Calmette-Guerin (BCG) vaccine in a humanized mouse model.

3 Jan 2023

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

The most comprehensive lung cell atlas to date, from the Wellcome Sanger Institute and collaborators, has revealed 11 new lung cell types and offers detailed insight into an immune process involved in fighting lung infections.

21 Dec 2022

Phenotypic plasticity may allow cancer cells to evade standard therapy

Glioblastomas (GBMs) are incurable brain tumors with a prognosis of about one-and-a half years on average. They are highly resistant to treatment and have defied all attempts at precision therapy.

20 Dec 2022

Novel approach could pave the way for new treatments to prevent relapse in breast cancer patients

Cambridge scientists have managed to identify and kill those breast cancer cells that evade standard treatments in a study in mice.

20 Dec 2022

Study provides deeper insights into skeletal muscle aging

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23, entitled, "Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence."

16 Dec 2022

Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, has globally infected more than 639 million individuals and claimed over 6.6 million lives. Despite the rapid commencement of COVID-19 vaccination programs in most countries across the world, the virus has remained in circulation.

30 Nov 2022

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

A new study links a gene concentrated in the brain's cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer's disease.

30 Nov 2022

What genes are associated with asthma exacerbations?

In a new study, researchers reviewed the genomics, transcriptomics, and epigenetics of asthma exacerbations (AEs).

29 Nov 2022

Characterization of bat viromes reveals the co-infection, spillover, and emergence risk of several zoonotic viruses

Researchers characterized the mammal-infecting viruses in 149 bats, representing six genera and 15 species, sampled from Yunnan province, China using an unbiased meta-transcriptomics approach.

28 Nov 2022

Microniches of intratumoral microbiota impact spatial and cellular heterogeneity in cancer

Researchers mapped spatial, cellular, and molecular interactions of host and tumor-associated bacteria within the tumor microenvironment.

22 Nov 2022

The vaginal microbiome through the lens of systems biology

A new paper recently published online in Trends in Microbiology journal reviews the systems biology approach to explore the vaginal microbiome (VMB), helping to understand its composition and function and the mechanisms by which it interacts with the host.

22 Nov 2022

Transcriptomics News and Research

Developing new tools to accelerate spatial genomics and drug discovery

NIH awards eight research grants to advance diagnosis of Multisystem Inflammatory Syndrome in Children

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

Phenotypic plasticity may allow cancer cells to evade standard therapy

Novel approach could pave the way for new treatments to prevent relapse in breast cancer patients

Study provides deeper insights into skeletal muscle aging

Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

What genes are associated with asthma exacerbations?

Characterization of bat viromes reveals the co-infection, spillover, and emergence risk of several zoonotic viruses

Microniches of intratumoral microbiota impact spatial and cellular heterogeneity in cancer

The vaginal microbiome through the lens of systems biology

The role of bacteria in cancer growth

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

Antibiotic-resistant, opportunistic pathogen enhances the pathogenesis of C. difficile

Researchers identify 35 genes that are highly expressed in patients with long-term Lyme disease

MGI opens its second overseas Customer Experience Center in Europe

MGI Partners with Imperial College London to Establish Overseas Customer Experience Center in the UK

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

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Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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