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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

Physical inactivity and inflammation drive age-related gene changes in skeletal muscles

New research indicates that some age-related changes in gene and protein expression in the skeletal muscles of older individuals may be affected more by physical inactivity and chronic inflammation than primary aging, or intrinsic maturational processes.

21 Feb 2024

Novel genetic associations with anxiety unveiled in comprehensive study of over 1.2 million people

The genetic basis of anxiety disorders, identify genetic loci, and calculate polygenic risk scores for anxiety.

20 Feb 2024

AI revolutionizes protein function prediction with "DeepGO-SE"

Researchers developed "DeepGO-SE," a novel AI method for predicting protein functions from sequences, significantly outperforming traditional models by incorporating gene ontology and protein-protein interactions.

15 Feb 2024

SARS-CoV-2 fragments found to mimic immune system peptides, fueling inflammation

Study reveals SARS-CoV-2 fragments mimic immune peptides, potentially driving the virus's inflammatory response, offering insights into COVID-19's severe inflammation mechanisms.

5 Feb 2024

Study identifies plasma markers linked to mental health in young adults

Study in "Translational Psychiatry" explores plasma proteins related to the p-factor in young adults, revealing potential biomarkers for overall mental health status and insights into common underlying factors of mental health disorders.

28 Jan 2024

Study finds patients with long COVID exhibit complement dysregulation with signs of thromboinflammation

Researchers explore inflammatory signatures restricted to patients with active post-acute COVID-19 sequelae.

23 Jan 2024

Long COVID and ME/CFS patients could benefit from a coordinated treatment strategy

People suffering from Long COVID or Myalgic Encephalomyelitis /Chronic Fatigue Syndrome (ME/CFS) could benefit from a coordinated treatment strategy, a new University of Otago study has found.

22 Jan 2024

Novel blood test shows promise in detecting early-stage cancers with high accuracy

Researchers develop a novel plasma proteome-based test for early detection of multiple cancers, achieving high accuracy in identifying low-abundance protein biomarkers.

14 Jan 2024

Glioblastoma tumor cells mimic neurons to evade treatment

Certain cancers are more difficult to treat because they contain cells that are highly skilled at evading drugs or our immune systems by disguising themselves as healthy cells.

11 Jan 2024

Chia genome sequenced, revealing potential health benefits

In a recent study published in Frontiers in Plant Science, researchers presented the assembly of the chia reference genome.

18 Dec 2023

Researchers report progress in the search for more accurate blood markers for acute kidney injury

Using cells from kidney biopsies, Johns Hopkins Medicine, researchers report progress in the search for more accurate and easier-to-obtain markers to help predict, manage and assess treatment of acute kidney injury (AKI).

14 Dec 2023

Is your body out of sync? Study finds organs age at varying rates

Research uncovers that human organs age at varying rates, with some showing accelerated aging compared to chronological age, significantly impacting overall health and disease risk. The study used advanced blood plasma proteomics to analyze organ-specific aging in nearly 5,700 adults, linking it to increased risks of heart failure and Alzheimer's disease.

7 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

Researchers performed a proteomic analysis to identify serologic indicators of organ aging and disease.

7 Dec 2023

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

A group of authors critically evaluated and interpreted the evidence linking mitochondrial dysfunction and metabolic changes to the pathogenesis of Alzheimer's disease (AD).

5 Dec 2023

Advances in understanding and detecting Alzheimer's disease

Researchers are making strides toward understanding and detecting Alzheimer's disease in its earliest stages, when interventions may be most effective at slowing the progress of the disease.

13 Nov 2023

Multi-ancestry study reveals 187 new genetic risk factors for prostate cancer

In a comprehensive multi-ancestry GWAS meta-analysis, researchers identified 451 risk variants for prostate cancer, including 187 new variants, demonstrating the utility of such studies across diverse populations. This analysis not only increased understanding of genetic risk factors but also differentiated between aggressive and non-aggressive prostate cancer types, underscoring the potential of genetic risk scoring in guiding screening and early detection strategies.

12 Nov 2023

Researchers announce a new genetic classification system for gastric cancer

Professor Sang Cheul Oh of the Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Professor Sang‑Hee Kang of the Department of Surgery, Korea University's Guro Hospital, and Professor Sun Young Yim of the Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine announced a new genetic classification system for gastric cancer by a multicenter study with the University of Texas MD Anderson Cancer Center.

6 Nov 2023

A comprehensive database developed to help understand the basis of protein aggregation

Researchers at the IBB-UAB have developed the most comprehensive database available to date to help understand the basis of protein aggregation, a phenomenon associated with aging and several pathologies.

3 Nov 2023

Researchers discover new mechanism of cancer treatment resistance

A surprising mechanism that makes some cancers treatment-resistant has been discovered by Weill Cornell Medicine and NewYork-Presbyterian investigators.

2 Nov 2023

Proteome News and Research

Physical inactivity and inflammation drive age-related gene changes in skeletal muscles

Novel genetic associations with anxiety unveiled in comprehensive study of over 1.2 million people

AI revolutionizes protein function prediction with "DeepGO-SE"

SARS-CoV-2 fragments found to mimic immune system peptides, fueling inflammation

Study identifies plasma markers linked to mental health in young adults

Study finds patients with long COVID exhibit complement dysregulation with signs of thromboinflammation

Long COVID and ME/CFS patients could benefit from a coordinated treatment strategy

Novel blood test shows promise in detecting early-stage cancers with high accuracy

Glioblastoma tumor cells mimic neurons to evade treatment

Chia genome sequenced, revealing potential health benefits

Researchers report progress in the search for more accurate blood markers for acute kidney injury

Is your body out of sync? Study finds organs age at varying rates

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

Advances in understanding and detecting Alzheimer's disease

Multi-ancestry study reveals 187 new genetic risk factors for prostate cancer

Researchers announce a new genetic classification system for gastric cancer

A comprehensive database developed to help understand the basis of protein aggregation

Researchers discover new mechanism of cancer treatment resistance

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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