Proteome News and Research

RSS

The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature."

31 Oct 2023

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

Integrated liquid-biopsy proteomics with single-cell transcriptomics from ocular cell types.

24 Oct 2023

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Salivary proteins may offer early detection for ectopic pregnancies, potentially saving maternal lives through a non-invasive diagnostic approach. The study identifies specific proteins that are prominently present in ruptured ectopic pregnancy cases, highlighting the potential for developing a saliva-based diagnostic kit.

9 Oct 2023

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Challenges associated with the development and design of neoantigen cancer vaccines.

5 Oct 2023

AlphaMissense revolutionizes genetic mutation analysis for disease prediction

AlphaMissense, an adaptation of AlphaFold, offers a highly accurate model for predicting the pathogenicity of human proteome-wide missense variants at the single amino acid level. The model outperforms existing methods, providing valuable insights for diagnosing rare diseases and developing targeted therapies.

20 Sep 2023

DeepMind develops new tool to predict pathogenicity of missense variants

DeepMind is releasing AlphaMissense, a tool researchers can use to learn more about the effects that missense mutations – which make up the majority of "variants of uncertain significance" – have on disease.

19 Sep 2023

MRI innovation to unveil iron homeostasis in the human brain

Researchers demonstrated a MRI method sensitive to the live brain's iron homeostasis (the r1-r2 extent of relaxation or relaxivity).

14 Sep 2023

A novel multi-epitope vaccine targeting extracellular proteins of Chlamydia pneumoniae

Researchers designed and evaluated a multi-epitope vaccine targeting the main outer membrane protein of Chlamydia pneumoniae using immunoinformatics.

14 Sep 2023

Research sheds light on the role of lipidome in human physiology

The sequencing of the human genome promised a revolution in medicine, but scientists soon realized that a genetic blueprint alone does not show the body in action.

11 Sep 2023

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Researchers investigated the impact of biological sex on protein levels and its genomic control by analyzing 1,277 proteomes of the brain.

4 Sep 2023

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Researchers found that short-term intensive fasting enhances the immune function of red blood cells, including their ability to combat SARS-CoV-2, without affecting their oxygen-carrying capacity. The study reveals that this fasting regimen popular in Asia could offer a multifaceted benefit by amplifying the body's defenses without compromising essential functions.

4 Sep 2023

Proteome News and Research

How one gene shakes up our understanding of male infertility

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

AlphaMissense revolutionizes genetic mutation analysis for disease prediction

DeepMind develops new tool to predict pathogenicity of missense variants

MRI innovation to unveil iron homeostasis in the human brain

A novel multi-epitope vaccine targeting extracellular proteins of Chlamydia pneumoniae

Research sheds light on the role of lipidome in human physiology

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Artificial intelligence and polyclonal antibody sequencing redefine the future of antibody discovery

Study explores the effects of different diets on plasma proteins

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

Genetic determinants of retinol circulation and their impact on health

What are some recent advancements in proteomics-driven pancreatic oncology research?

How does the circulating proteome influence brain health?

Study finds α5 integrin as a potential therapeutic target in amyotrophic lateral sclerosis

New protein discovered in Alzheimer's brains could lead to better diagnosis and treatment

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest News