Life Sciences Thought Leaders

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News Medical's "Thought Leaders" series is a selection of articles written by national and international experts and trusted advisers in the life sciences industry. All the articles are written by experts who have been invited as recognised leaders in their fields to provide a "state of the art" contribution.

Developing high field solid-state NMR for the characterization of complex targets

Solid-state NMR spectroscopy is a technique used by scientists to provide valuable information in the analysis of solid materials. It provides unique and specific insights into the structure, dynamics, and reactivity of all kinds of materials.

From Bruker BioSpin - NMR, EPR and Imaging 10 Jan 2017

Giving polycystic kidney disease the bump

We launched this campaign at the beginning of October 2016. It's the first time that we've ever had a campaign of this size and scope. It's a European campaign in multiple languages that's coordinated by six of the organizations that represent PKD patients in Europe.

5 Jan 2017

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

How can we tackle antimicrobial resistance?

Antimicrobial resistance happens when bugs, like bacteria, fungi or viruses, change, or evolve, when they’re exposed to drugs, like antibiotics, antifungals, or antivirals. Bugs that develop antimicrobial resistance are sometimes referred to as ‘superbugs’.

20 Dec 2016

Metabolomics research at the Phenome Centre Birmingham

An interview with Professor Mark Viant, University of Birmingham, UK, Executive Director of Phenome Centre Birmingham and Director of the NERC Biomolecular Analysis Facility.

From Bruker BioSpin - NMR, EPR and Imaging 28 Nov 2016

Nano-biointeraction and nanopathology

Nanoparticles enter the organism in a number of ways. In most cases through inhalation and ingestion. When inhaled, the majority of them are expelled with the next breath. When ingested, most of them are gotten rid of through feces.

31 Oct 2016

Solid-state NMR in structural biology: an interview with Professor Tatyana Polenova

My research lab studies several classes of systems. We are mostly interested in looking at large protein assemblies to understand their structure, dynamics and how their properties relate to their malfunction in disease.

From Bruker BioSpin - NMR, EPR and Imaging 21 Sep 2016

Could a light-listening photonics device detect skin disease? An interview with Prof. Vasilis Ntziachristos

Detection of malignant skin alterations is currently aided by optical microscopes such as dermoscopes or optical microscopes. While the latter offers high resolution, it comes with a major disadvantage, just like any other purely microscopic method: it only provides a partial view of the skin due to the low penetration depth.

29 Aug 2016

Advances in brain research since patient HM: an interview with Dr Jacopo Annese

Jacopo Annese, President and CEO of the Institute for Brain and Society, discusses his work on the Human Brain Library.

From Huron Digital Pathology 25 Aug 2016

Could nanotechnology turn the cancer cell suicide switch back on? An interview with Professor Dipanjan Pan

Before I explain the discovery, I would take a step back and explain an interesting event that takes place in the cancer cells. Normal cells follow a rapid and irreversible process to efficiently eradicate dysfunctional cells. This is a natural process by which damaged cells commit ‘suicide’. This process is known as apoptosis or programmed cell death.

15 Aug 2016

Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

“IDPs” is now a widely used acronym that stands for “intrinsically disordered proteins.” It is the term generally used by the scientific community to refer to a wide variety of proteins that do not have a stable 3D structure and are instead characterized by a high extent of local mobility, disorder and many conformers that are accessible at room temperature.

From Bruker BioSpin - NMR, EPR and Imaging 30 Jun 2016

Using Spectral Imaging to Study Brain Tumors in 3D

I’m a biophysicist at the University of Bordeaux and I mainly work on bio-imaging methods in the cancer laboratory research facility, mostly for brain cancers.

From Daylight Solutions Inc 13 Jun 2016

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Professor Claudio Luchinat, University of Florence and co-founder of the Magnetic Resonance Center (CERM), speaks to News-Medical about his research in NMR-based metabolomics.

From Bruker BioSpin - NMR, EPR and Imaging 9 Jun 2016

Could whole-mount scanning of breast tissue lead to better clinical outcomes? An interview with Dr Martin Yaffe

We actually normally refer to this as whole-specimen imaging of breast tissue.

From Huron Digital Pathology 24 May 2016

Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

To me the most exciting aspect of pre-clinical imaging is its broad range, from very basic science up to applied science. You deal with a range of disciplines including biology, chemistry, physics, biochemistry, biophysics, cell biology and of course medicine, as the aim is the translation of research to humans.

From Bruker BioSpin - NMR, EPR and Imaging 27 Apr 2016

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

In our bioanalytical mass spectrometry lab we use proteomics techniques to try to understand more about Alzheimer's disease. The primary thrust of our research is that we're interested in understanding the changes that take place outside of the brain and how those correlate with what's taking place inside the brain

From Pittcon 21 Apr 2016

Advances in NMR metabolomics: an interview with Professor Tone F. Bathen

The main objective of our research is to improve and individualize cancer diagnostics and cancer treatment. We try to achieve this through the integrated use of MR technology and the development of data-driven tools to analyze tumors on both a functional and molecular level.

From Bruker BioSpin - NMR, EPR and Imaging 11 Apr 2016