Life Sciences Thought Leaders

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News Medical's "Thought Leaders" series is a selection of articles written by national and international experts and trusted advisers in the life sciences industry. All the articles are written by experts who have been invited as recognised leaders in their fields to provide a "state of the art" contribution.

Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar

Most proteins are involved in interactions with one or a few functional ligands, but some proteins, like light chain 8 (LC8), have numerous binding partners. LC8 interacts with more than 100 functionally different proteins, from viral proteins to motor proteins to proteins involved in cell division.

From Bruker BioSpin - NMR, EPR and Imaging 18 Feb 2016

Unlocking intrinsically disordered proteins: an interview with Peter Wright

I'm a professor in the Department of Integrative Structural and Computational Biology at The Scripps Research Institute. I have been performing NMR research on proteins for nearly 40 years.

From Bruker BioSpin - NMR, EPR and Imaging 11 Feb 2016

Molecular imaging and radiochemistry: the importance of instrumentation. An interview with Professor Björn Wängler

Interview conducted with Professor Björn Wängler, Professor for Molecular Imaging and Radiochemistry from Heidelberg University.

From Bruker BioSpin - NMR, EPR and Imaging 4 Feb 2016

Using centrifugal elutriation and flow cytometry to answer biological questions: an interview with Peter Lopez

Flow Cytometry, the measurement of various cellular characteristics as they flow through a measuring apparatus, has so many applications.

From Beckman Coulter Life Sciences - Centrifugation 27 Jan 2016

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

Single fluorescent molecules provide a local nanometer-sized probe of complex systems. We can measure the motion of the single molecule, use them to achieve imaging on a scale down to 20 nanometers, or we can infer aspects of the behaviour of the object under study by the details of the light that is emitted.

From Pittcon 26 Jan 2016

Determining Ectopeptidase Activity: An Interview with Professor Stephen Weber, University of Pittsburgh

The scope of the activity of neuropeptides is remarkably broad. For example, neuropeptides are involved in pain control, mood/depression/eating disorders, social and emotional behaviour, body weight, drug abuse, stress, reproduction, motor control, memory, and in maintaining neuronal health when they are stressed.

From Pittcon 14 Jan 2016

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

My laboratory’s long standing interest is the study of the signaling capabilities of stem cells, both under homeostatic conditions

From Beckman Coulter Life Sciences - Flow Cytometry 5 Jan 2016

Can Nanostructured Microelectrodes be Used to Analyze Biomarkers? An Interview with Dr Shana Kelley

Electrochemical methods are appealing because simple and inexpensive instrumentation can be used to make highly sensitive measurements. However, it has been quite difficult to realize clinically-relevant levels of sensitivity using electrochemistry in highly complex, real-world samples.

From Pittcon 15 Dec 2015

Liposomal sizing and the Coulter principle: an interview with Professor Melvin E. Klegerman

For about the last 25 years, the cardiology group here have been developing a platform technology for both the diagnosis and treatment of atherosclerosis.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 28 Oct 2015

Pipetting Solutions for Sample Screening

Our research focuses on interleukin 1 and the inflammasome and their role in innate immunity and inflammation.

From INTEGRA Biosciences 16 Sep 2015

MPI applications: an interview with Tobias Knopp, University Hospital Hamburg

Up to now, we've seen a lot of improvements made, but now we're almost at the point of focusing on the application of MPI and proving what the real benefits of this technology are, which is very exciting...

From Bruker BioSpin - NMR, EPR and Imaging 12 Jul 2015

Transitioning Infrared Imaging into Clinical Use

The CLIRSPEC network is a UK Engineering and Physical Sciences Research Council (EPSRC – EP/L012952/1) funded network in clinical infrared and Raman spectroscopy. Infrared and Raman spectroscopy can identify the hallmarks of disease and distinguish between diseased and non-diseased samples based upon inherent chemistry.

From Daylight Solutions Inc 7 Jul 2015

The future of MPI: an interview with Dr Nikolaos Panagiotopoulos, University Hospital Schleswig Holsten

I’m Dr Panagiotopoulos and I am a resident at the University Hospital of Schleswig-Holstein. I work in the Radiological and Nuclear Medicine Department, at the Lübeck campus.

From Bruker BioSpin - NMR, EPR and Imaging 5 Jul 2015

Angiography and MPI: an interview with Professor Mauro Magnani University of Urbino

I am Mauro Magnani, Professor of Biochemistry at the University of Urbino, Italy. My background is essentially the transition of activity from the lab to application. I am also the founder of a spin-off company called EryDel, which uses technology to load materials or drugs inside cells.

From Bruker BioSpin - NMR, EPR and Imaging 30 Jun 2015

Preclinical Magnetic Particle Imaging: an interview with Professor Jeff Bulte, Johns Hopkins

I'm Jeff Bulte, professor of Radiology and Director of Cellular Imaging at the Institute for Cell Engineering at Johns Hopkins University School of Medicine, Baltimore, Maryland in the United States. I lead a group of about 20 to 25 people who focus their research on imaging cells.

From Bruker BioSpin - NMR, EPR and Imaging 24 Jun 2015

T cell expansion technology: an interview with Alexander Malykhin, CVPF, University of Pennsylvania

T cells are taken from the patient’s blood and then modified using lentivirus, adenovirus or RNA electroporation.

From Beckman Coulter Life Sciences - Flow Cytometry 5 May 2015

Women in science: an interview with Professor Dame Carol Robinson, University of Oxford

Professor Dame Carol Robinson has just been announced as the “L’Oréal-UNESCO For Women In Science” European Laureate for 2015...

14 Apr 2015

Compact MRI and multimodality: an interview with Bernard Siow, UCL

CABI is a preclinical imaging laboratory where we have about ten modalities. We started off with MRI and we have a 9.4T high-field system.

From Bruker BioSpin - NMR, EPR and Imaging 30 Mar 2015

Multimodality at the Center for Advanced Biomedical Imaging: an interview with Professor Mark Lythgoe, UCL

Imaging techniques used to live in medical physics departments, where physicists worked on them, but now we're seeing biologists, cell biologists and developmental biologists looking at cellular processes and it's those advances that are really enabling imaging to move forward in a way that it hasn't previously been able to...

From Bruker BioSpin - NMR, EPR and Imaging 25 Mar 2015

Epigenetics and women’s health research: an interview with Professor Steve Conlan, Swansea University

Our research into gynaecological oncology focuses around understanding mechanisms of how genes are regulated or how they become dysregulated in a disease; and also the effects that has on the surface of the endometrium and also the function of the ovaries...

From Chromatrap® - Porvair Sciences Ltd 24 Feb 2015