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Focusing on clinical drug research for dementia

Frontiers in Clinical Drug Research - Dementia is a book series which presents comprehensive reviews about research on Dementia, a term which references the loss of brain function associated with Alzheimer's disease and other related medical conditions.

5 Jun 2020

Using gene therapy to help the body to make its own cancer drugs

Imagine that we could instruct our bodies to make the drugs they need themselves. The gene technology that makes this possible is called mRNA therapy, which may become a major tool in the treatment of multiple diseases.

29 May 2020

New therapeutic approach for aggressive breast cancer

This type of TNBC tumor does not express any of the receptors involved in most breast cancers (estrogen, progesterone and HER2), so the most common treatments, such as the hormone therapy, are not viable in these patients.

25 May 2020

Magnetic core-shell iron nanowires can be used for noninvasive medical imaging

Living cells inside the body could be placed under surveillance--their location and migration noninvasively tracked in real time over many days--using a new method developed by researchers at KAUST.

20 May 2020

Researchers develop a new, promising treatment for HIV

A novel means to prevent HIV infection was developed at the University of Nebraska Medical Center that could allow people with or at risk of acquiring the virus to take medicines once a year.

28 Apr 2020

Rice University wins prestigious grant to develop new therapies for sickle cell disease

A Rice University lab has won a prestigious National Institutes of Health grant to pursue gene-editing research it hopes will lead to a cure for sickle cell disease (SCD).

25 Apr 2020

Graphene-based nanomedicine enables targeted cancer treatment at molecular level

"Three" kinds of regalia such as crown, orb, and sward are often necessary to be a high king for conquering the world. For fighting off cancerous diseases, what do we need? This "triple" chemical modified nanomaterial might be save the patient.

23 Apr 2020

Nanotechnology-based treatment can help alleviate fertility problems linked to endometriosis

Scientists have developed a precise, nanotechnology-based treatment to alleviate the pain and fertility problems associated with endometriosis, a common gynecological condition in women of childbearing age.

7 Apr 2020

NYU Abu Dhabi researchers develop nanocarrier for more effective cancer drug delivery

A team of researchers at NYU Abu Dhabi has developed a biocompatible, biodegradable, and economical nanocarrier for safer and more effective delivery of anticancer drugs.

3 Mar 2020

Magnetically levitated plasma proteins could vastly improve diagnosis of diseases

Researchers at Michigan State University's Precision Health Program have helped develop a fascinating new method for detecting the density of proteins in the blood - a method that could vastly improve the rate at which diseases are detected and diagnosed.

5 Feb 2020

Tailored mesoporous silica particles could be used to treat obesity, diabetes

Engineered ingestible molecular traps created from mesoporous silica particles (MSPs) introduced to the gut can have an effect on food efficiency and metabolic risk factors. The results from studies on mice, published in Nanomedicine, demonstrate the potential to reduce the energy uptake into the body and could lead to new treatments for obesity and diabetes.

14 Jan 2020

A controlled phage therapy to target drug-resistant pathogens

The fight against drug-resistant pathogens remains an intense one. While the Centers for Disease Control's 2019 "biggest threats" report reveals an overall decrease in drug-resistant microbe-related deaths as compared to its previous report (2013) the agency also cautions that new forms of drug-resistant pathogens are still emerging.

13 Jan 2020

Nano-sized copper compounds together with immunotherapy can kill cancer cells

An interdisciplinary team of scientists from KU Leuven, the University of Bremen, the Leibniz Institute of Materials Engineering, and the University of Ioannina has succeeded in killing tumour cells in mice using nano-sized copper compounds together with immunotherapy. After the therapy, the cancer did not return.

9 Jan 2020

Biodegradable nanoparticle can deliver 'suicide gene' to pediatric brain tumor cells in mice

Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a "suicide gene" to pediatric brain tumor cells implanted in the brains of mice.

8 Jan 2020

Synthetic mRNA nanoparticles restore tumor suppressor gene, make cancer cells susceptible to drugs

In preclinical experiments, investigators restored p53 using synthetic mRNA nanoparticles, making lung and liver cancer cells susceptible to available cancer drugs.

23 Dec 2019

Artificial 'inclusion bodies' developed for sustained release of therapeutic proteins

Precision medicine is becoming increasingly important, achieving to create more efficient personalized therapies for each patient and innovative pharmacological developments.

19 Dec 2019

MR Solutions participates in the first SFNano & C’Nano joint meeting 2019

UK based MR Solutions presented a simultaneous 7T PET/MRI preclinical imaging system optimized for nanoparticle imaging to the first joint annual congress of the French Nanomedicine Society (SFNano), and the French national Competency Cluster in Nanoscience C’Nano which was held in Dijon in early December.

From MR Solutions 17 Dec 2019

New nanoparticle innovation detects vascular calcification in atherosclerosis

Heart disease and stroke are the world's two most deadly diseases, causing over 15 million deaths in 2016 according to the World Health Organization.

9 Dec 2019

Researchers design new antitumoral drug release strategy for breast cancer treatment

The local release of antitumoral drugs through bacterial proteins in the treatment of breast cancer can mark a before and after in precision medicine.

21 Nov 2019

Research finds particular subclass of 'bad cholesterol' is a much better predictor of heart attacks

New research at Ohio University shows that a particular subclass of low-density lipoproteins (LDL), also known as "bad cholesterol," is a much better predictor of potential heart attacks than the mere presence of LDL, which is incorrect more often than not.

18 Nov 2019