Alzheimer's & Dementia

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

GLP-1 Receptor Agonists in Alzheimer’s Disease: Emerging Off-Label Neuroprotective Potential

GLP-1 receptor agonists show strong preclinical neuroprotective potential in Alzheimer’s disease through effects on insulin signaling, neuroinflammation, amyloid, tau, and brain metabolism. Human evidence remains mixed, with observational studies suggesting lower dementia risk but randomized trials yet to demonstrate a clinically meaningful disease-modifying benefit.

What is Mixed Dementia?

Mixed Dementia Prevention and Treatment

Mixed Dementia Symptoms and Diagnosis

Gender and Alzheimer’s Risk

Differences Between Alzheimer's and Dementia

Amyloid Cascade Hypothesis

Pollution and Alzheimer's

Does Depression and Anxiety Increase the Risk of Dementia?

Dementia Diagnosis

What Causes Dementia?

Alzheimer's and Veganism

See more featured articles »

Mythbusting: Misconceptions in Dementia

AAM - The Search for a Cure to Alzheimer's

Can Statins Protect Against Alzheimer’s Disease?

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Dementia with Lewy Bodies

Alzheimer's Disease Questions

Dancing Through Dementia: How Movement Aids Memory and Mood

Alzheimer’s Disease and Gingko Biloba

Antidepressants and Dementia: Is There a Link?

Antibody Research and Alzheimer’s Disease

Alzheimer's Disease and the Microbiome

Can Happiness Protect You from Dementia?

Alzheimer's Disease and Sleep Disruption

Omega-3 and Alzheimer’s Disease

Alzheimer's Disease Causes

Stress and Alzheimer's Disease

What is Dementia?

Alzheimer’s Disease and Calcium Supplements

Dementia Symptoms

Inflammation and Alzheimer's Disease

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Does Herpesvirus Cause Alzheimer's?

Diet and Alzheimer's Disease

Integrated PET/MR for Alzheimer’s Disease

Childhood Dementia Signs and Symptoms

AAM - Genetics of Alzheimer's

Designing Dementia-Friendly Environments

Transcutaneous Electrical Nerve Stimulation for Dementia

Is Alzheimer's Disease Transmissible?

Dementia Prevention

Childhood Dementia Causes

Alzheimer's Disease Prevention

AAM - Air pollution and Alzheimer's

What are Amyloid Plaques?

Aromatherapy for Dementia

Biomarkers for Alzheimer's Disease

Alzheimer’s tangles and plaques: what’s the difference?

Alzheimer's Disease Treatments

Bright Light Therapy and Dementia

Alzheimer’s Disease | Definition, Causes, Diagnosis & Treatment

Stem Cell Therapy for Alzheimer's

Alzheimer's Disease Diagnosis

Dementia Treatment

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Types of Alzheimer's Disease

Alzheimer's Disease Epidemiology

Migraines and Dementia

Coconut Oil and Dementia

Alzheimer's Disease Symptoms

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Latest Alzheimer's & Dementia News and Research

Researchers find alarming rates of CTE in former football players

In a new study from Mass General Brigham, Boston University (BU), and the Concussion & CTE Foundation, researchers found evidence that at least 1-in-4 former NFL players who died between 2016 and 2021 had chronic traumatic encephalopathy (CTE) at the time of their death, a much higher prevalence compared to the general population.

25 Aug 2026

Novel blood-based method diagnoses Alzheimer’s disease with high accuracy

Alzheimer's disease (AD) accounts for 60–80% of global dementia cases, with its core pathological feature being the misfolding and aggregation of β-amyloid (Aβ) proteins in the brain.

25 Aug 2026

Dysfunctional myelin-producing brain cells contribute to age-related cognitive decline

Brain cells that produce the protective coating around nerve fibers can become dysfunctional with age and may actively contribute to cognitive decline, according to new research.

25 Aug 2026

Study reveals high prevalence of chronic traumatic encephalopathy among former NFL players

At minimum, nearly a quarter of all former National Football League (NFL) players who died from 2016 to 2021 had confirmed chronic traumatic encephalopathy (CTE) – a neurodegenerative disease linked to repeated head impacts – at death, finds a study published by The BMJ today.

25 Aug 2026

What decades of wine research can, and cannot, tell us about health

A narrative review found that moderate wine intake has repeatedly been associated with lower all-cause and cardiovascular mortality, with proposed mechanisms involving ethanol and grape-derived polyphenols, but the evidence remains largely observational and cannot establish causation. The authors argue that drinking pattern, beverage type, age, cancer risk, and risk-modeling choices all influence how the J-shaped association should be interpreted and how alcohol guidelines are developed.

25 Aug 2026

The diet-Alzheimer’s connection is more complicated than “eat this, avoid that”

A mini-review finds that dietary patterns may influence Alzheimer’s disease through interconnected pathways involving neuroinflammation, insulin resistance, oxidative stress, blood-brain barrier dysfunction, homocysteine, and the gut-brain axis. The authors argue that genetics, sex, age, physical activity, and socioeconomic context may modify these relationships, supporting more individualized approaches to nutrition research and dementia prevention.

25 Aug 2026

Shared protein pathology redefines treatment for multiple neurodegenerative diseases

On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem like unrelated diseases.

24 Aug 2026

Researchers explore the link between tau levels and depressive symptoms in older people

During typical aging and Alzheimer's disease progression, higher levels of a protein called tau are associated with more depressive symptoms.

24 Aug 2026

Older brains' language processing network remains resilient to aging

As people age, many cognitive functions tend to decline. Brain scanning studies have revealed corresponding changes in the function of a brain network that is involved in many of these cognitive functions, including working memory and problem-solving.

24 Aug 2026

Disrupted brain-immune signaling may help drive neurodegeneration

A Cell perspective argues that neurodegeneration can emerge from disrupted communication between neural and immune networks, with peripheral immunity, microglia, and gene-regulatory programs all shaping disease processes. The authors propose that restoring immune homeostasis and recalibrating neuroimmune circuits could create new therapeutic and diagnostic opportunities, while emphasizing that many mechanisms remain unresolved in humans.

24 Aug 2026

FDA clears innovative blood test for earlier Alzheimer's diagnosis

The U.S. Food and Drug Administration (FDA) has cleared for marketing an innovative blood test with underlying technology invented at Washington University School of Medicine in St. Louis for the early diagnosis of Alzheimer's disease.

21 Aug 2026

New review highlights spatial technologies in advanced brain mapping

Understanding how molecular changes shape brain function and disease requires more than measuring genes in bulk tissue.

21 Aug 2026

Lancet review examines possible amyloid-beta transmission through blood transfusions

A review and opinion piece published in The Lancet and led by UCL (University College London) and UCLH researchers discusses the possibility that blood transfusions may inadvertently transmit harmful brain proteins, and whether additional safety measures are warranted as a precaution whilst further research is conducted to better understand these potential risks.

21 Aug 2026

Microglial differences found in genetic and sporadic frontotemporal dementia patients

A study by the University of Eastern Finland revealed for the first time clear differences in the function and gene expression of microglial cells from patients with genetic and sporadic types of frontotemporal dementia.

20 Aug 2026

Two distinct types of brain tissue work together to support cognition in older adults

Researchers from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have found that two distinct types of brain tissue work together to support cognition in older adults, and that the health of the brain's short-range wiring may help soften the cognitive effects of gray matter loss.

20 Aug 2026

Skull bone marrow contains immune hubs that fight brain cancer

Researchers at Washington University School of Medicine in St. Louis have discovered lymph node-like structures in the skull bone marrow of mice for the first time and demonstrated that they act as rapid first responders against brain cancer before distant lymph nodes get the signal that abnormal cells are present.

19 Aug 2026

Re:Cognition Health launches first dedicated Alzheimer's disease-modifying treatment clinic in Ireland

Re:Cognition Health, the UK's largest independent provider of Alzheimer's disease-modifying treatments, announces the opening of its first Irish clinic in Dublin, marking a major milestone in dementia care for Ireland.

19 Aug 2026

Brain changes detect Alzheimer's seven years before plaques appear

A new study suggests that Alzheimer's disease may be detected by brain imaging more than seven years earlier than previously assumed. Researchers from the Department of Psychology at the University of Oslo led the study, published in Nature Neuroscience.

19 Aug 2026

Leisure-time exercise linked to lower dementia risk

For years, scientists have known that regular physical activity can help lower the risk of dementia. But new USC research suggests that it's not only the amount but also the activity's context - for work or for leisure - that makes a difference.

18 Aug 2026

UVA researchers find how postoperative delirium may set the stage for dementia

UVA Health researchers have discovered how a form of delirium that often strikes older patients after surgery may set the stage for dementia – and identified a drug that could reverse the underlying brain changes.

18 Aug 2026