Alzheimer's & Dementia

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

GLP-1 Receptor Agonists in Alzheimer’s Disease: Emerging Off-Label Neuroprotective Potential

GLP-1 receptor agonists show strong preclinical neuroprotective potential in Alzheimer’s disease through effects on insulin signaling, neuroinflammation, amyloid, tau, and brain metabolism. Human evidence remains mixed, with observational studies suggesting lower dementia risk but randomized trials yet to demonstrate a clinically meaningful disease-modifying benefit.

Childhood Dementia Signs and Symptoms

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Diet and Alzheimer's Disease

AAM - Genetics of Alzheimer's

Biomarkers for Alzheimer's Disease

Bright Light Therapy and Dementia

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Differences Between Alzheimer's and Dementia

Alzheimer's Disease Causes

Dementia Symptoms

Mixed Dementia Symptoms and Diagnosis

See more featured articles »

Does Depression and Anxiety Increase the Risk of Dementia?

Alzheimer's Disease Epidemiology

What is Mixed Dementia?

Integrated PET/MR for Alzheimer’s Disease

Designing Dementia-Friendly Environments

Dementia Treatment

Aromatherapy for Dementia

Alzheimer's Disease Treatments

Dementia Diagnosis

Alzheimer's and Veganism

Dancing Through Dementia: How Movement Aids Memory and Mood

What are Amyloid Plaques?

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

What is Dementia?

Can Statins Protect Against Alzheimer’s Disease?

Is Alzheimer's Disease Transmissible?

Alzheimer's Disease and Sleep Disruption

AAM - The Search for a Cure to Alzheimer's

Alzheimer's Disease and the Microbiome

Omega-3 and Alzheimer’s Disease

Migraines and Dementia

Stress and Alzheimer's Disease

Alzheimer’s Disease and Calcium Supplements

Does Herpesvirus Cause Alzheimer's?

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Alzheimer's Disease Symptoms

Gender and Alzheimer’s Risk

Mythbusting: Misconceptions in Dementia

What Causes Dementia?

Antidepressants and Dementia: Is There a Link?

Pollution and Alzheimer's

Inflammation and Alzheimer's Disease

Stem Cell Therapy for Alzheimer's

Types of Alzheimer's Disease

Alzheimer’s Disease and Gingko Biloba

Dementia with Lewy Bodies

Mixed Dementia Prevention and Treatment

Can Happiness Protect You from Dementia?

AAM - Air pollution and Alzheimer's

Alzheimer's Disease Questions

Alzheimer’s Disease | Definition, Causes, Diagnosis & Treatment

Dementia Prevention

Alzheimer's Disease Diagnosis

Antibody Research and Alzheimer’s Disease

Alzheimer's Disease Prevention

Transcutaneous Electrical Nerve Stimulation for Dementia

Childhood Dementia Causes

Coconut Oil and Dementia

Amyloid Cascade Hypothesis

Alzheimer’s tangles and plaques: what’s the difference?

Latest Alzheimer's & Dementia News and Research

Blood-brain barrier-crossing blood pressure drugs linked to lower dementia risk

In a large Australian cohort of adults with hypertension, use of blood-brain barrier-crossing antihypertensive medications was associated with a lower risk of dementia and mortality than use of non-crossing drugs. The association was strongest for beta-blockers and angiotensin II receptor blockers, although the observational design means the findings cannot establish causality.

27 Aug 2026

Parkinson’s disease imposes €22.8 billion economic burden across Europe

The annual societal cost of Parkinson's disease across Europe reached €22.8 billion in 2019, equivalent to €28.8 billion at 2025 prices, a new study published today in Movement Disorders has shown.

27 Aug 2026

Study links later-life food insecurity to elevated dementia risk

Older adults who experienced food insecurity in both midlife and later life had nearly four times the risk of probable dementia as those who remained food secure, according to new University of Michigan research.

27 Aug 2026

HRT linked to lower dementia risk, but timing and menopause type matter

In a UK Biobank study of 183,450 postmenopausal women followed for an average of 13.3 years, hormone replacement therapy use was associated with a modestly lower risk of dementia, with stronger associations in women who had surgical menopause or shorter natural estrogen exposure. The relationship also varied by age at HRT initiation, while the observational design means the findings cannot establish that HRT prevents dementia.

27 Aug 2026

Salk researchers isolate specific neurons controlling complex social behaviors

Our brains constantly integrate information about both our internal state and our surroundings to determine how we behave.

27 Aug 2026

Egg yolk peptides protect brain cells from oxidative stress

As the human lifespan increases, so too does the risk of developing neurological disorders such as Parkinson's disease, Alzheimer's disease, anxiety and depression.

27 Aug 2026

Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration

Brain diseases, including dementia, have long been studied using experimental animals such as mice.

27 Aug 2026

Multi-ancestry genetic score improves risk prediction for Alzheimer's disease

Late-onset Alzheimer disease (AD) is a progressive disorder characterized by cognitive decline and memory impairment, affecting an estimated 6.9 million people in the U.S.

27 Aug 2026

Brain shrinkage biomarker may predict early-onset Alzheimer’s progression

In people diagnosed with early-onset Alzheimer's disease, a biomarker tool that detects shrinkage of the brain's gray matter may predict how quickly someone may progress from mild cognitive impairment (MCI) to dementia, according to a new study published August 26, 2026, in Neurology, an official journal of the American Academy of Neurology.

27 Aug 2026

Brain atrophy on MRI could help predict Alzheimer’s progression

Mass General Brigham Neuroscience Institute researchers have found that a pattern of brain atrophy visible on MRI could help predict how quickly people with early-onset Alzheimer's disease progress from mild cognitive impairment to dementia.

27 Aug 2026

Faulty myelin-making brain cells may help drive cognitive decline with age

Researchers found that greater age-related cognitive decline was associated with more dysfunctional oligodendrocytes, reduced NRF2 expression, smaller myelinated axons, and abnormally thicker myelin in human white matter. Experiments in mice showed that deleting NRF2 specifically from oligodendrocytes reproduced key white matter abnormalities and reduced cognitive improvement over time, implicating this pathway in cognitive aging.

26 Aug 2026

A major NFL brain study puts new numbers on the burden of CTE

Researchers analyzed 1,712 former NFL players who died between 2008 and 2021, including 338 brain donors, to estimate the possible prevalence of chronic traumatic encephalopathy (CTE) at death and its association with dementia. At least 24.5% of players who died from 2016 to 2021 had confirmed CTE, while stage IV CTE among brain donors was associated with a 44% higher risk of clinician-adjudicated dementia.

26 Aug 2026

Nanoparticles regenerate neurons and improve cognition in Alzheimer’s mice

The adult human brain has limited capacity to repair or regenerate neurons lost to Alzheimer's disease, the most common type of dementia.

26 Aug 2026

Specific brain regions found more vulnerable to dementia with Lewy bodies

Dementia with Lewy bodies is one of the most common forms of dementia in older adults, after Alzheimer's disease.

26 Aug 2026

Molecular switch ERBB4 linked to broad range of Alzheimer's pathologies

What if amyloid plaques are not the whole story of Alzheimer's disease? New research suggests that a broad range of Alzheimer's pathologies may be orchestrated by a molecular switch called ERBB4 when it turns on in the wrong neurons.

26 Aug 2026

Hormone replacement therapy may reduce dementia risk for some women

Hormone replacement therapy (HRT) may reduce the risk of dementia, particularly for certain groups of women - according to a study from the University of East Anglia and the University of Exeter.

26 Aug 2026

Researchers find alarming rates of CTE in former football players

In a new study from Mass General Brigham, Boston University (BU), and the Concussion & CTE Foundation, researchers found evidence that at least 1-in-4 former NFL players who died between 2016 and 2021 had chronic traumatic encephalopathy (CTE) at the time of their death, a much higher prevalence compared to the general population.

25 Aug 2026

Novel blood-based method diagnoses Alzheimer’s disease with high accuracy

Alzheimer's disease (AD) accounts for 60–80% of global dementia cases, with its core pathological feature being the misfolding and aggregation of β-amyloid (Aβ) proteins in the brain.

25 Aug 2026

Dysfunctional myelin-producing brain cells contribute to age-related cognitive decline

Brain cells that produce the protective coating around nerve fibers can become dysfunctional with age and may actively contribute to cognitive decline, according to new research.

25 Aug 2026

Study reveals high prevalence of chronic traumatic encephalopathy among former NFL players

At minimum, nearly a quarter of all former National Football League (NFL) players who died from 2016 to 2021 had confirmed chronic traumatic encephalopathy (CTE) – a neurodegenerative disease linked to repeated head impacts – at death, finds a study published by The BMJ today.

25 Aug 2026