Alzheimer's & Dementia

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

GLP-1 Receptor Agonists in Alzheimer’s Disease: Emerging Off-Label Neuroprotective Potential

GLP-1 receptor agonists show strong preclinical neuroprotective potential in Alzheimer’s disease through effects on insulin signaling, neuroinflammation, amyloid, tau, and brain metabolism. Human evidence remains mixed, with observational studies suggesting lower dementia risk but randomized trials yet to demonstrate a clinically meaningful disease-modifying benefit.

Amyloid Cascade Hypothesis

Dementia Treatment

Integrated PET/MR for Alzheimer’s Disease

Alzheimer's and Veganism

Dementia Prevention

AAM - The Search for a Cure to Alzheimer's

Alzheimer's Disease and Sleep Disruption

Does Depression and Anxiety Increase the Risk of Dementia?

Can Statins Protect Against Alzheimer’s Disease?

Is Alzheimer's Disease Transmissible?

Biomarkers for Alzheimer's Disease

See more featured articles »

Migraines and Dementia

AAM - Genetics of Alzheimer's

Alzheimer’s tangles and plaques: what’s the difference?

Alzheimer's Disease Symptoms

Mythbusting: Misconceptions in Dementia

Can Happiness Protect You from Dementia?

Stem Cell Therapy for Alzheimer's

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Antibody Research and Alzheimer’s Disease

What is Dementia?

Aromatherapy for Dementia

Alzheimer's Disease Treatments

Childhood Dementia Causes

Diet and Alzheimer's Disease

Mixed Dementia Prevention and Treatment

Inflammation and Alzheimer's Disease

Does Herpesvirus Cause Alzheimer's?

Alzheimer’s Disease and Calcium Supplements

Alzheimer's Disease and the Microbiome

Pollution and Alzheimer's

Alzheimer's Disease Questions

Gender and Alzheimer’s Risk

AAM - Air pollution and Alzheimer's

Stress and Alzheimer's Disease

Types of Alzheimer's Disease

Dementia Diagnosis

Bright Light Therapy and Dementia

Dementia with Lewy Bodies

Antidepressants and Dementia: Is There a Link?

Alzheimer's Disease Epidemiology

Childhood Dementia Signs and Symptoms

Mixed Dementia Symptoms and Diagnosis

Omega-3 and Alzheimer’s Disease

Designing Dementia-Friendly Environments

Alzheimer’s Disease and Gingko Biloba

Alzheimer's Disease Prevention

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

What is Mixed Dementia?

What are Amyloid Plaques?

Dementia Symptoms

What Causes Dementia?

Alzheimer's Disease Causes

Coconut Oil and Dementia

Alzheimer’s Disease | Definition, Causes, Diagnosis & Treatment

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Differences Between Alzheimer's and Dementia

Alzheimer's Disease Diagnosis

Transcutaneous Electrical Nerve Stimulation for Dementia

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Dancing Through Dementia: How Movement Aids Memory and Mood

Latest Alzheimer's & Dementia News and Research

Older AI-estimated heart age linked to worse health outcomes

Having an older heart age estimated using artificial intelligence (AI) ultrasound analysis compared with actual age was associated with worse outcomes, according to results presented today at the ESC Digital & AI Summit 2026.

13 Nov 2026

Aging reduces the brain's waste-flushing process during sleep

As people age, they may sleep for shorter periods and wake up more frequently during the night. In addition to those disruptions, MIT researchers have now discovered that a process responsible for flushing waste from the brain during sleep is commonly impaired in older people.

13 Nov 2026

Your brain may reveal your Alzheimer’s risk before symptoms appear

Researchers developed the ARC brain connectivity score to distinguish cognitive resilience from vulnerability and improve early Alzheimer’s risk assessment.

13 Nov 2026

New light-based tool reveals how cells regulate autophagy

Inside each cell is a dynamic world of molecules and chemicals, signals and receivers, and construction and destruction.

12 Nov 2026

Liver-derived protein helps protect brain cells and improves memory in Alzheimer's mice

Researchers identified 92 circulating proteins that cross the blood-brain barrier and enter brain tissue, revealing how proteins such as liver-derived APOA1 help regulate astrocyte cholesterol metabolism and support neuronal synapses. In an Alzheimer's disease mouse model, APOA1 transport was impaired, but increasing its production in the liver reduced selected inflammatory and amyloid-related abnormalities, improved synaptic integrity, and enhanced some measures of memory.

12 Nov 2026

Type 2 diabetes significantly increases risk of developing Alzheimer's disease

A Curtin University-led review has revealed type 2 diabetes significantly raises risk of developing Alzheimer's disease.

12 Nov 2026

Researchers associate personality shifts with frontotemporal dementia functional decline

Frontotemporal dementia often results in early changes in personality or behavior before changes in cognitive skills.

12 Nov 2026

Meta analysis quantifies annual Alzheimer's incidence in type 2 diabetes

A Curtin University-led review has revealed type 2 diabetes significantly raises risk of developing Alzheimer's disease.

12 Nov 2026

Rare genetic mutation may protect against Parkinson's and Lewy body dementia

A rare genetic mutation may protect against developing Parkinson's disease and Lewy body dementia, a new study from researchers at Oregon Health & Science University suggests.

11 Nov 2026

Exercise benefits mental health, so why is the genetic evidence so mixed?

A systematic review of 61 Mendelian randomization studies found limited and inconsistent genetic evidence that general physical activity causally improves mental health or cognitive outcomes; 30 studies reported only null or directionally opposite findings. More consistent evidence emerged for aerobic exercise and reduced depression risk, and for physical fitness traits, particularly muscle strength and muscle mass, in relation to better mental and cognitive health, although methodological limitations prevent definitive causal conclusions.

11 Nov 2026

UCSF launches global study tracking real-world psychedelic experiences

Most psychedelic experiences don't happen in research labs. To better understand their effects, UC San Francisco scientists are going where the experiences are and launching a global study to track what psychedelics do to people's brains, bodies and well-being.

10 Nov 2026

$32 million grant extends landmark Alzheimer's research through 2031

When Leonard Berg, MD, then a neurologist at Washington University School of Medicine in St. Louis, noticed memory problems among his older patients in the 1970s, he refused to dismiss the problems as part of "normal aging" or senility but instead set out to understand what was happening in their brains.

10 Nov 2026

Scientists scanned people's brains before and after 45 days of yoga. Here's what changed

In a randomized controlled trial involving 139 healthy adults, 45 days of a standardized yoga program improved mood, self-reported sleep quality, and selected short-term memory measures compared with a waitlist control group. Brain scans from 43 participants also revealed changes in functional connectivity across networks involved in movement, attention, language, and cognitive processing, although the long-term significance remains uncertain

10 Nov 2026

Could eating more mushrooms help protect your brain as you age?

A review of existing research suggests that ergothioneine, a natural antioxidant found primarily in mushrooms, may protect brain cells against oxidative stress, inflammation, and damage associated with Alzheimer's and Parkinson's diseases. Although laboratory and animal studies show promising neuroprotective effects, human evidence remains limited, and larger clinical trials are needed to determine whether supplementation can prevent or slow neurodegeneration.

10 Nov 2026

Targeting brain cleaning gene could help treat or prevent Alzheimer's

A gene responsible for compacting trash inside the brain appears to be a key player in Alzheimer's disease, and doctors may be able to target it to better treat or help prevent the devastating condition, new UVA Health research suggests.

10 Nov 2026

Subtle changes in deep sleep before Alzheimer's symptoms appear

The study identifies slow-wave sleep alterations as potential biomarkers for Alzheimer's, emphasizing their role in cognitive health and disease progression.

10 Nov 2026

Meeting WHO's air pollution guidelines could save nine million lives

Meeting the World Health Organization's recommended annual guidelines for air pollution resulting from fine particulate matter and nitrogen dioxide has the potential to save more than 9 million lives a year in low- and middle-income countries, say University of Cambridge researchers.

10 Nov 2026