Alzheimer's & Dementia

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

Alzheimer’s Disease | Definition, Causes, Diagnosis & Treatment

Alzheimer’s Disease (AD) is the most common form of dementia worldwide (60-70% of all dementia cases) and is a progressive neurodegenerative disorder.

Childhood Dementia Causes

Alzheimer’s Disease and Calcium Supplements

What is Dementia?

Dementia Prevention

Designing Dementia-Friendly Environments

AAM - Genetics of Alzheimer's

Alzheimer's Disease and the Microbiome

Dementia Symptoms

Integrated PET/MR for Alzheimer’s Disease

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Alzheimer's Disease and Sleep Disruption

See more featured articles »

Antidepressants and Dementia: Is There a Link?

Antibody Research and Alzheimer’s Disease

Alzheimer's Disease Questions

Alzheimer's Disease Symptoms

Mythbusting: Misconceptions in Dementia

Childhood Dementia Signs and Symptoms

Amyloid Cascade Hypothesis

Alzheimer's Disease Epidemiology

Does Depression and Anxiety Increase the Risk of Dementia?

Coconut Oil and Dementia

Alzheimer's Disease Causes

Alzheimer's Disease Diagnosis

Stress and Alzheimer's Disease

Is Alzheimer's Disease Transmissible?

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Can Happiness Protect You from Dementia?

Alzheimer's Disease Prevention

Biomarkers for Alzheimer's Disease

Dementia with Lewy Bodies

What is Mixed Dementia?

Differences Between Alzheimer's and Dementia

AAM - Air pollution and Alzheimer's

Can Statins Protect Against Alzheimer’s Disease?

What are Amyloid Plaques?

Pollution and Alzheimer's

Gender and Alzheimer’s Risk

What Causes Dementia?

Dancing Through Dementia: How Movement Aids Memory and Mood

Omega-3 and Alzheimer’s Disease

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Alzheimer’s tangles and plaques: what’s the difference?

Does Herpesvirus Cause Alzheimer's?

Types of Alzheimer's Disease

Mixed Dementia Prevention and Treatment

Migraines and Dementia

Alzheimer’s Disease and Gingko Biloba

Dementia Treatment

Alzheimer's Disease Treatments

Stem Cell Therapy for Alzheimer's

Aromatherapy for Dementia

Transcutaneous Electrical Nerve Stimulation for Dementia

Inflammation and Alzheimer's Disease

Alzheimer's and Veganism

AAM - The Search for a Cure to Alzheimer's

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Diet and Alzheimer's Disease

Dementia Diagnosis

Mixed Dementia Symptoms and Diagnosis

Bright Light Therapy and Dementia

Latest Alzheimer's & Dementia News and Research

Evidence links gut microbiome changes to Alzheimer’s progression

Human studies consistently report gut microbiome differences in mild cognitive impairment and Alzheimer’s disease, but findings vary widely by cohort, methods, and taxa. Heterogeneity and limited longitudinal data prevent causal inference, highlighting the need for functional profiling and well-designed intervention trials.

25 Jan 2026

Selective inhibition of cPLA2 shows promise against Alzheimer's-related brain inflammation

A multidisciplinary USC research team has identified new compounds that may target a key driver of brain inflammation linked to Alzheimer's disease. Their research just published in the Nature publication npj Drug Discovery.

24 Jan 2026

Experimental study reveals advanced episodic memory replay in rats

In a new study Indiana University researchers observed episodic memory in rats to a degree never documented before, suggesting that rats can serve as a model for complex cognitive processes often considered exclusively human.

24 Jan 2026

Genetic study establishes causal link between obesity and cognitive decline

People with obesity and high blood pressure may face a higher risk of dementia, according to a new study published in The Journal of Clinical Endocrinology & Metabolism.

23 Jan 2026

Ageing slows brain protein clearance and shifts synaptic waste to microglia

Ageing slows neuronal protein degradation in mice, leading to widespread accumulation and aggregation of long-lived proteins, particularly at synapses. As neuronal clearance declines, microglia selectively accumulate synaptic proteins, suggesting a compensatory but potentially strained proteostasis pathway in the ageing brain.

22 Jan 2026

Nearly half of adults now live with heart disease as obesity and diabetes surge

The 2026 American Heart Association Heart Disease and Stroke Statistics report shows that nearly half of adults are living with cardiovascular disease, with cardiometabolic risk factors projected to rise substantially by 2050. Despite progress in smoking reduction and cholesterol control, worsening obesity, diabetes, hypertension, sleep health, and persistent inequities threaten future cardiovascular health.

22 Jan 2026

Brain complexity declines in Alzheimer's disease

As individuals with Alzheimer's disease (AD) move from the mild cognitive impairment stage to moderate and severe dementia, complex awareness deteriorates although lower-level sensory awareness is relatively maintained.

22 Jan 2026

High BMI linked to vascular dementia risk

High body mass index (BMI) could cause a higher risk of vascular-related dementia (a combination of vascular + unspecified dementia), according to new research from the University of Bristol and University Hospital of Copenhagen (Rigshospitalet and Herlev-Gentofte hospital).

22 Jan 2026

Unfolding the role of Hsp70 chaperones in neurodegeneration

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, yet treatments remain largely limited to symptom management.

22 Jan 2026

Regular aerobic exercise slows a key marker of brain aging in midlife

Regular aerobic activity significantly reduces brain-PAD, indicating that exercise is crucial for maintaining brain health and reducing dementia risk.

22 Jan 2026

Lifelong health: The Northern Finland Birth Cohort 1966 enters a new era of aging research

One of the world’s most extensive birth cohorts is now entering later adulthood. At the University of Oulu in Finland, the Northern Finland Birth Cohort 1966 (NFBC1966) is launching a major new follow-up combining decades of biological, social, and environmental data with modern digital health tools to examine how lifelong exposures and the genome shape health and aging.

22 Jan 2026

Red light therapy may protect athletes' brains from repetitive impacts

Punch-drunk syndrome, boxer's madness, chronic traumatic encephalopathy (CTE). The name has changed over the years, but the cause is clear: repeated impacts can affect long-term brain health, with symptoms ranging from confusion to memory loss and potentially dementia.

21 Jan 2026

Pandemic linked to lasting drops in diagnosis rates for major conditions

There has been a lasting and disproportionate impact of the Covid-19 pandemic on diagnosis rates for conditions including depression, asthma and osteoporosis.

21 Jan 2026

Long-term air pollution exposure raises motor neuron disease risk

Long-term exposure to ambient air pollution was associated with a higher risk of developing motor neuron disease and poorer prognosis after diagnosis in a large nationwide Swedish study. Higher particulate matter and nitrogen dioxide exposure were also linked to faster functional decline and increased likelihood of invasive ventilation.

21 Jan 2026

Shingles vaccination is linked to slower biological aging in older adults

This population-based study of U.S. adults aged 70 and older found that shingles vaccination was associated with slower epigenetic and transcriptomic aging, as well as lower systemic inflammation. No significant associations were observed for neurodegeneration or cardiovascular biomarkers, highlighting domain-specific molecular effects rather than broad clinical changes.

21 Jan 2026

Exercise-triggered mitochondrial transfer offers hope for stroke and dementia

Physical rehabilitation and symptom management still remain the mainstay of treatment for stroke, as clot removal or dissolution is effective only within a narrow time frame after the stroke.

21 Jan 2026

The neuroscience of motivation-driven memory retention

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and Duke University have proposed a neuroscience framework explaining how different types of motivation fundamentally reshape what and how the brain remembers.

21 Jan 2026

Tracing the decline in American heart disease mortality

Following a five-year upward trend likely impacted by the COVID pandemic, the number of heart disease and stroke deaths has declined, yet, heart disease and stroke still kill more people in the U.S. each year than any other cause, according to data reported in the 2026 Heart Disease and Stroke Statistics: A Report of U.S. and Global Data From the American Heart Association.

21 Jan 2026

New AI framework mirrors human physiology to understand emotional experiences

Emotions are a fundamental part of human psychology-a complex process that has long distinguished us from machines.

20 Jan 2026

Rhythmic carbon dioxide exposure may enhance brain waste clearance mechanisms

Abnormal clumps of proteins like α-synuclein, amyloid beta and tau are associated with neurodegenerative conditions like Parkinson's and Alzheimer's disease, but a waste removal mechanism called the glymphatic pathway can clear these proteins and other metabolic byproducts from the brain.

20 Jan 2026