Alzheimer's & Dementia

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

GLP-1 Receptor Agonists in Alzheimer’s Disease: Emerging Off-Label Neuroprotective Potential

GLP-1 receptor agonists show strong preclinical neuroprotective potential in Alzheimer’s disease through effects on insulin signaling, neuroinflammation, amyloid, tau, and brain metabolism. Human evidence remains mixed, with observational studies suggesting lower dementia risk but randomized trials yet to demonstrate a clinically meaningful disease-modifying benefit.

AAM - The Search for a Cure to Alzheimer's

Can Happiness Protect You from Dementia?

Alzheimer's Disease Treatments

Alzheimer's Disease Causes

Dementia Diagnosis

Dementia Treatment

Can Statins Protect Against Alzheimer’s Disease?

Does Depression and Anxiety Increase the Risk of Dementia?

Alzheimer’s Disease and Gingko Biloba

Amyloid Cascade Hypothesis

Alzheimer's Disease Questions

See more featured articles »

Bright Light Therapy and Dementia

Alzheimer’s Disease | Definition, Causes, Diagnosis & Treatment

Alzheimer’s tangles and plaques: what’s the difference?

Diet and Alzheimer's Disease

Childhood Dementia Causes

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Aromatherapy for Dementia

Dancing Through Dementia: How Movement Aids Memory and Mood

Is Alzheimer's Disease Transmissible?

What is Mixed Dementia?

Alzheimer's and Veganism

Omega-3 and Alzheimer’s Disease

Mythbusting: Misconceptions in Dementia

What Causes Dementia?

Stem Cell Therapy for Alzheimer's

Designing Dementia-Friendly Environments

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

AAM - Air pollution and Alzheimer's

Alzheimer's Disease and Sleep Disruption

Mixed Dementia Prevention and Treatment

What is Dementia?

Coconut Oil and Dementia

Alzheimer's Disease Epidemiology

Gender and Alzheimer’s Risk

Does Herpesvirus Cause Alzheimer's?

Alzheimer's Disease and the Microbiome

Alzheimer’s Disease and Calcium Supplements

Mixed Dementia Symptoms and Diagnosis

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Types of Alzheimer's Disease

Alzheimer's Disease Symptoms

Dementia with Lewy Bodies

Migraines and Dementia

Antibody Research and Alzheimer’s Disease

Transcutaneous Electrical Nerve Stimulation for Dementia

What are Amyloid Plaques?

Pollution and Alzheimer's

Stress and Alzheimer's Disease

AAM - Genetics of Alzheimer's

Biomarkers for Alzheimer's Disease

Alzheimer's Disease Diagnosis

Integrated PET/MR for Alzheimer’s Disease

Dementia Prevention

Alzheimer's Disease Prevention

Differences Between Alzheimer's and Dementia

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Dementia Symptoms

Childhood Dementia Signs and Symptoms

Inflammation and Alzheimer's Disease

Antidepressants and Dementia: Is There a Link?

Latest Alzheimer's & Dementia News and Research

Frailty linked to greater cognitive impairment risk in men with chronic kidney disease

New research from the University of Colorado Anschutz Department of Medicine is shedding light on how women and men with chronic kidney disease (CKD) may fare differently as they age and their disease progresses.

23 Sep 2026

Transient ischemic attacks linked to increased long-term dementia risk

Having a transient ischemic attack (TIA) is associated with an increased risk of developing dementia, according to a new study published September 23, 2026, in Neurology, the medical journal of the American Academy of Neurology.

23 Sep 2026

PsychAD studies map molecular mechanisms across major brain disorders

Research led by Mount Sinai scientists within the PsychAD Consortium, a large-scale, multidisciplinary initiative launched in 2019 with support from the National Institute on Aging (NIA), is featured in a landmark collection of nine papers published across the Nature family of journals that maps the molecular mechanisms underlying Alzheimer's disease, Parkinson's disease, schizophrenia, and other brain disorders.

23 Sep 2026

Menopause leaves a blood protein signature linked to brain aging and Alzheimer’s risk

Researchers identified a 16-protein blood signature associated with menopause that tracked more strongly with reproductive hormones than chronological age and was largely replicated in an independent UK Biobank cohort. Higher menopause proteomic scores were also associated with less favorable proteomic aging estimates and poorer cognitive outcomes in older women, including incident Alzheimer’s dementia, although the observational evidence does not establish causality.

23 Sep 2026

Experimental drug reverses multiple sclerosis damage in mouse model

A drug developed by a UVA Health scientist has not only stopped but reversed paralysis and vision loss in a mouse model of multiple sclerosis.

23 Sep 2026

New 3D lipid atlas maps the chemistry of mouse brains

The brain is often described in terms of cells and wiring. However, much of it is made of lipids that form the membranes of neurons, wrap nerve fibers with myelin, and help brain cells send and receive signals.

23 Sep 2026

People with dementia can participate in research without experiencing significant burden

A multidisciplinary study conducted at the University of Eastern Finland has shown that people with dementia and their caregivers can participate in demanding research without experiencing a significant burden.

23 Sep 2026

C-Path awards $1.7 million to advance five drug development projects

Critical Path Institute (C-Path) today announced that its Translational Therapeutics Accelerator has awarded $1,699,500 through five Bridging Research and Innovation in Drug Development Grants (BRIDGe).

22 Sep 2026

Loneliness and social isolation cost people years of healthy life

The numbers paint a grim picture. Roughly half of all U.S. adults are lonely, according to a 2023 report, and nearly as many feel socially isolated.

22 Sep 2026

Low spinal bone density may predict faster brain aging

Researchers at Johns Hopkins University found that lower bone mineral density in the spine was associated with faster cognitive decline and accelerated age-related white matter injury, according to a new study published today in Radiology, a journal of the Radiological Society of North America.

22 Sep 2026

KAIST researchers develop NUDGE technology to steer cell fate

Which genes need to be controlled to guide a stem cell toward a desired cell type, or to modulate an immune cell's inflammatory response? A Korean research team has developed a general-purpose computational framework that identifies the key targets needed to steer a cell toward a desired state with a single temporary intervention, without permanently altering its genes.

22 Sep 2026

Brain Health WA resource aims to reduce dementia risk

With Western Australia projected to record the nation's fastest growth in dementia cases, a new Curtin University-led resource aims to help people protect their brain health and reduce their risk.

22 Sep 2026

Galimedix establishes Scientific Advisory Board for Alzheimer’s disease to guide development of novel oral drug candidate, GAL-101

Galimedix Therapeutics, Inc., a Phase 2 clinical-stage biotechnology company developing novel oral and topical neuroprotective therapies with the potential to revolutionize the treatment of serious brain and eye diseases, today announced the establishment of a dedicated Alzheimer's Disease Scientific Advisory Board (SAB).

From Galimedix Therapeutics, INC. 22 Sep 2026

High cognitive impairment rates among homeless people demand radical policy change

Cognitive impairment is a prevalent but often unaddressed factor in chronic homelessness, and it must be addressed to help reduce homelessness, argues the author of a commentary published in CMAJ

21 Sep 2026

New brain circuit discovery offers hope for panic disorder treatments

Our survival depends on brains that constantly search for danger and, if found, stay alert until it has passed.

21 Sep 2026

Active form of meprin-β protein increases in people with Alzheimer’s disease

A team from the Altered Molecular Mechanism in Alzheimer's Disease and Dementia laboratory, led by Javier Sáez Valero, a researcher at the Institute for Neurosciences (IN), a joint centre of the Miguel Hernández University of Elche (UMH) and the Spanish National Research Council (CSIC), has identified increased levels of the protein meprin-β in the brain and cerebrospinal fluid of people with Alzheimer's disease.

21 Sep 2026

Older adults with higher polyphenol intake were less likely to have mild cognitive impairment

In a cross-sectional study of 92 older Italian memory-clinic patients, higher habitual intake of total dietary (poly)phenols and several specific subclasses was associated with a lower likelihood of mild cognitive impairment (MCI). Total (poly)phenol intake was not associated with cognitive test performance or circulating inflammatory biomarkers, and the authors cautioned that the small observational study cannot establish causality.

20 Sep 2026

Study identifies brain mechanism behind pregnancy-related food cravings

Why do food cravings become so strong during pregnancy? Researchers at LSU's Pennington Biomedical Research Center, in collaboration with colleagues, have identified a brain mechanism that may help explain how pregnancy changes the motivation to seek certain highly palatable foods.

18 Sep 2026

Otolaryngologists gather to present latest advances in ear, nose, and throat care

The latest treatments and research advances in ear, nose, and throat care will take center stage in Los Angeles October 17-20, when more than 5,000 of the world's leading otolaryngologists gather for the 2026 Annual Meeting & OTO EXPO of the American Academy of Otolaryngology–Head and Neck Surgery Foundation.

18 Sep 2026

Better fitness was linked to healthier brain structure, but not better memory

Researchers studying 353 cognitively unimpaired adults aged 60 to 94 found that higher muscular capacity was associated with lower basal ganglia perivascular space volume, while greater aerobic fitness was associated with greater gray matter volume and medial temporal lobe thickness. Fitness was not directly associated with global cognition or episodic memory, and evidence for cognitive reserve was limited, although VO₂max explained additional variation in delayed verbal memory beyond tau burden.

18 Sep 2026