Alzheimer's & Dementia

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

GLP-1 Receptor Agonists in Alzheimer’s Disease: Emerging Off-Label Neuroprotective Potential

GLP-1 receptor agonists show strong preclinical neuroprotective potential in Alzheimer’s disease through effects on insulin signaling, neuroinflammation, amyloid, tau, and brain metabolism. Human evidence remains mixed, with observational studies suggesting lower dementia risk but randomized trials yet to demonstrate a clinically meaningful disease-modifying benefit.

Alzheimer's Disease and Sleep Disruption

Mixed Dementia Prevention and Treatment

Can Statins Protect Against Alzheimer’s Disease?

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Alzheimer’s Disease | Definition, Causes, Diagnosis & Treatment

Inflammation and Alzheimer's Disease

Alzheimer’s Disease and Calcium Supplements

What is Dementia?

Aromatherapy for Dementia

Antibody Research and Alzheimer’s Disease

Stem Cell Therapy for Alzheimer's

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Pollution and Alzheimer's

Alzheimer's Disease Epidemiology

Alzheimer’s Disease and Gingko Biloba

Transcutaneous Electrical Nerve Stimulation for Dementia

Dementia Prevention

Amyloid Cascade Hypothesis

Alzheimer's Disease Prevention

Alzheimer's Disease Diagnosis

Childhood Dementia Causes

Alzheimer's and Veganism

Bright Light Therapy and Dementia

Designing Dementia-Friendly Environments

Alzheimer's Disease Causes

Dancing Through Dementia: How Movement Aids Memory and Mood

Does Depression and Anxiety Increase the Risk of Dementia?

Does Herpesvirus Cause Alzheimer's?

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Dementia Symptoms

Mythbusting: Misconceptions in Dementia

What are Amyloid Plaques?

Stress and Alzheimer's Disease

Mixed Dementia Symptoms and Diagnosis

Gender and Alzheimer’s Risk

Dementia Diagnosis

AAM - The Search for a Cure to Alzheimer's

Is Alzheimer's Disease Transmissible?

Alzheimer's Disease Questions

Types of Alzheimer's Disease

AAM - Genetics of Alzheimer's

Childhood Dementia Signs and Symptoms

Differences Between Alzheimer's and Dementia

Antidepressants and Dementia: Is There a Link?

AAM - Air pollution and Alzheimer's

Dementia Treatment

Coconut Oil and Dementia

Alzheimer's Disease Treatments

Omega-3 and Alzheimer’s Disease

Dementia with Lewy Bodies

Migraines and Dementia

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Biomarkers for Alzheimer's Disease

Alzheimer's Disease Symptoms

Alzheimer’s tangles and plaques: what’s the difference?

Alzheimer's Disease and the Microbiome

Can Happiness Protect You from Dementia?

Diet and Alzheimer's Disease

Integrated PET/MR for Alzheimer’s Disease

What Causes Dementia?

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

What is Mixed Dementia?

Latest Alzheimer's & Dementia News and Research

Living in disadvantaged neighborhoods linked to adverse brain health

In a study analyzing nearly 3,000 brain MRI exams, researchers found that living in highly disadvantaged neighborhoods was associated with adverse brain health.

15 Sep 2026

Reading for pleasure linked to better mental health and greater empathy

Reading for pleasure – from tucking into a Jane Austen classic to devouring a Heartstopper graphic novel – is linked to better mental health, greater empathy and a lower risk of dementia, say researchers.

15 Sep 2026

Study explains why Amazonian Indigenous populations show low dementia prevalence

In two Indigenous communities living pre-industrial lifestyles in the Bolivian Amazon, dementia is remarkably uncommon.

15 Sep 2026

Menopause may not drive rising pulse pressure and midlife aortic stiffness in women

Contradicting conventional wisdom, menopause may not be the driving force behind an increase in aortic stiffness in women after midlife, according to new, independent research published today in Hypertension, a peer-reviewed scientific journal published by the American Heart Association journal.

15 Sep 2026

Study links processed foods to targeted domain-specific cognitive decline

An unhealthy Western-style diet was associated with a faster cognitive decline in people with a genetic risk of Alzheimer's disease, according to new research led by Murdoch University and Alzheimer's Research Australia.

15 Sep 2026

Eye scans detect signs of atrial fibrillation years before diagnosis

People with atrial fibrillation have signs of the condition in the retinas of their eyes that can be detected as early as four years before diagnosis, finds a new study led by University College London (UCL) and Moorfields researchers.

14 Sep 2026

APOE genotype helps p-tau217 predict who may develop cognitive impairment sooner

A pooled analysis of 8,582 adults from seven prospective cohorts found that higher plasma p-tau217 concentrations were associated with greater cognitive impairment risk and earlier progression, with stronger associations among APOE-ε4 carriers. Each 1-SD increase in p-tau217 was associated with a 24% shorter time to cognitive impairment among carriers compared with 13% among non-carriers, suggesting that genetic background can refine the prognostic meaning of this Alzheimer’s disease blood biomarker.

14 Sep 2026

Brain interference explains why multitasking becomes difficult

Multitasking feels like a required skill in modern life, but as anyone who has tried keeping track of multiple chat windows, an email inbox, and a stream of phone notifications during a video call can tell you, figuring out which messages are important comes at a cost.

10 Sep 2026

Dementia prevention should look beyond individual choices, study finds

Efforts to prevent dementia may be placing too much responsibility on people's choices while overlooking the wider social and environmental conditions that shape brain health, according to new Curtin University research published in The Lancet Public Health.

9 Sep 2026

Pink noise boosts brain waste clearance during sleep

During the day, waste products such as lactic acid and worn-out proteins build up in the brain. When we sleep at night, waves of cerebrospinal fluid (CSF) help to wash away this waste, keeping the brain healthy.

9 Sep 2026

New blood screening algorithm reduces unnecessary Alzheimer's PET scans

A new blood-based screening algorithm dramatically reduced the number of unnecessary PET scans needed to recruit patients at risk of Alzheimer's disease for a clinical trial, according to research from scientists at the Keck School of Medicine of USC published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

9 Sep 2026

Scientists traced a hidden immune route that may worsen tau-linked brain damage

In a mouse model of tauopathy, conventional type 1 dendritic cells (cDC1s) cross-presented brain-derived antigens in deep cervical lymph nodes, priming CD8+ T cells that accumulated in the brain and promoted neurodegeneration. Disrupting cDC1s or their cross-presentation activity reduced CD8+ T-cell infiltration and protected against neuronal loss, while human primary tauopathy samples also showed increased brain CD8+ T cells, although cDC1 involvement in humans remains unconfirmed.

6 Sep 2026

Younger and older brains respond differently to traumatic injury

Conventional wisdom holds that younger brains are better equipped to recover from injury. Their greater flexibility allows them to adapt, rebuild connections and compensate for damage in ways older brains often cannot.

4 Sep 2026

Community brain health programs successfully improve attention in older adults

As aging populations drive rising global healthcare demands, finding scalable ways to prevent cognitive decline has become a vital public health priority.

4 Sep 2026

What your gut microbes may have to do with how your brain ages

This review examines how diet-driven changes in the gut microbiota and microbial metabolites may influence cognitive aging through immune, metabolic, neural, endocrine, and barrier-related pathways. It highlights SCFAs, tryptophan-derived metabolites, and bile acids as key signaling mediators while emphasizing that much of the mechanistic evidence remains preclinical and human evidence is largely associative.

3 Sep 2026

As life expectancy rises, healthy aging is more important than ever

Global disease burden is shifting toward aging-related conditions as people live longer, with these diseases now representing the largest expected lifetime health burden for newborns across all income groups. Modeling suggests that reducing aging-related disease could produce unusually large and progressively greater gains in both longevity and healthy life expectancy because improvements in survival and health reinforce one another.

3 Sep 2026

Coffee, tea and dementia risk: Why the amount you drink could matter

A targeted perspective synthesizes epidemiological and mechanistic evidence examining how caffeine consumption during midlife may influence dementia risk later in life. The authors highlight potential roles for dose, age, CYP1A2 genotype, adenosine signaling and cultural drinking practices, while stressing that current observational evidence cannot establish causality.

3 Sep 2026

Brain-protecting immune cells may actually drive Alzheimer's disease

Immune cells that normally protect the body from damage by attacking foreign or infected cells are found in the brains of patients with Alzheimer's disease and related disorders at much higher levels than in healthy brains.

3 Sep 2026

Neural networks reveal how training shapes learning in living brains

A new study has used a type of machine learning called a neural network to reveal how different kinds of training can change how learning happens-both in machines, and in living brains.

3 Sep 2026

Menopause may start changing the gut years before periods stop

A longitudinal study of 964 women found that blood markers of gut epithelial barrier dysfunction and microbial product translocation began to rise around 2 to 2.5 years before the final menstrual period and remained elevated after menopause. The findings suggest that changes in gut barrier integrity may form part of the biological transition through menopause and could help explain links between menopause, inflammation, and later health outcomes.

2 Sep 2026