Alzheimer's & Dementia

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

GLP-1 Receptor Agonists in Alzheimer’s Disease: Emerging Off-Label Neuroprotective Potential

GLP-1 receptor agonists show strong preclinical neuroprotective potential in Alzheimer’s disease through effects on insulin signaling, neuroinflammation, amyloid, tau, and brain metabolism. Human evidence remains mixed, with observational studies suggesting lower dementia risk but randomized trials yet to demonstrate a clinically meaningful disease-modifying benefit.

Antidepressants and Dementia: Is There a Link?

Pollution and Alzheimer's

Alzheimer’s Disease and Calcium Supplements

AAM - The Search for a Cure to Alzheimer's

Alzheimer's Disease and Sleep Disruption

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Dementia Symptoms

Mythbusting: Misconceptions in Dementia

Can Happiness Protect You from Dementia?

Aromatherapy for Dementia

Inflammation and Alzheimer's Disease

See more featured articles »

What is Dementia?

Alzheimer's Disease Epidemiology

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Integrated PET/MR for Alzheimer’s Disease

Migraines and Dementia

Does Depression and Anxiety Increase the Risk of Dementia?

Does Herpesvirus Cause Alzheimer's?

Transcutaneous Electrical Nerve Stimulation for Dementia

Dementia with Lewy Bodies

Alzheimer’s tangles and plaques: what’s the difference?

Dementia Prevention

Designing Dementia-Friendly Environments

Dementia Diagnosis

Alzheimer's Disease Diagnosis

Can Statins Protect Against Alzheimer’s Disease?

Alzheimer's Disease Treatments

What are Amyloid Plaques?

Alzheimer’s Disease | Definition, Causes, Diagnosis & Treatment

Alzheimer’s Disease and Gingko Biloba

Alzheimer's and Veganism

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Is Alzheimer's Disease Transmissible?

AAM - Genetics of Alzheimer's

Types of Alzheimer's Disease

Dancing Through Dementia: How Movement Aids Memory and Mood

Childhood Dementia Causes

Omega-3 and Alzheimer’s Disease

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Alzheimer's Disease Causes

Mixed Dementia Symptoms and Diagnosis

Gender and Alzheimer’s Risk

Stress and Alzheimer's Disease

Dementia Treatment

Childhood Dementia Signs and Symptoms

Coconut Oil and Dementia

Alzheimer's Disease and the Microbiome

What is Mixed Dementia?

Biomarkers for Alzheimer's Disease

Differences Between Alzheimer's and Dementia

Antibody Research and Alzheimer’s Disease

Bright Light Therapy and Dementia

Alzheimer's Disease Prevention

Stem Cell Therapy for Alzheimer's

Diet and Alzheimer's Disease

Alzheimer's Disease Symptoms

Mixed Dementia Prevention and Treatment

What Causes Dementia?

Amyloid Cascade Hypothesis

AAM - Air pollution and Alzheimer's

Alzheimer's Disease Questions

Latest Alzheimer's & Dementia News and Research

Novel 'speech clock' can estimate a person's chronological age

A large study shows that machine-learning clocks based on speech can estimate chronological age and may also offer a window into brain aging, biological aging, cognitive health, cumulative burden, and dementia.

30 Sep 2026

Swedish study links lower midlife cognitive scores to future strokes

Adults in their 60s who scored lower on tests of overall thinking ability, memory and how quickly they processed information were more likely to have a stroke years later, according to new research conducted in Sweden, published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

30 Sep 2026

Neck lymph node removal surgery may disrupt brain waste clearance

Surgery to remove lymph nodes in the neck may interfere with cerebrospinal fluid (CSF) drainage from the brain, contributing to cognitive impairment, according to new multicenter research led by Weill Cornell Medicine scientists.

29 Sep 2026

What older adults do on screens may matter more than total screen time

Across 8,996 older adults in four cohorts, television viewing was associated with poorer global cognition, while computer use was associated with better cognitive performance, with the strongest positive associations at low-to-moderate levels of use. Mendelian randomization supported these opposing patterns and linked genetically predicted television viewing time to lower left insula volume, which accounted for an estimated 14.8% of its association with poorer cognitive performance.

29 Sep 2026

Greater variation in blood pressure associated with higher risk of death and strokes

Greater variation in blood pressure between research visits was associated with a higher risk of death in a study of more than 57,000 UK Biobank participants.

29 Sep 2026

New antibody treatment blocks immune response to prevent Alzheimer's damage

There is no treatment available today to stop the death of brain cells in neurodegenerative diseases known as tauopathies, including Alzheimer's disease, in which twisted clumps of a protein called tau accumulate in the brain.

28 Sep 2026

Insomnia linked to increased risk of stroke and hospital admissions

Insomnia is not only associated with poor sleep and reduced daytime functioning, but may also be an indicator of increased health risks.

28 Sep 2026

Study links insomnia to higher stroke and hospitalization risks

Insomnia is associated with a 26% higher risk of stroke and 28% higher odds of hospital admission, according to new research in Sleep Medicine Reviews. The researchers say the findings support recognizing insomnia as an important marker of brain, mental and general health.

28 Sep 2026

Could the Mediterranean diet protect the brain through the gut?

A narrative review finds that the Mediterranean diet may support brain health through gut microbiome, immune, metabolic, and barrier-related pathways, but direct human evidence that microbiome remodeling mediates neuroprotection remains limited. The proposed mechanisms involve microbial metabolites, reduced inflammatory signaling, stronger intestinal and blood-brain barrier function, and possible effects on processes linked to Alzheimer’s and Parkinson’s diseases.

27 Sep 2026

Mathematical models simulate how common metals influence Alzheimer's disease

What can mathematics reveal about Alzheimer's disease? Mississippi State Associate Professor Shantia Yarahmadian is using mathematical modeling to examine how common metals may influence a protein that forms plaque associated with Alzheimer's disease-and how potential therapies could alter these processes.

25 Sep 2026

Laser irradiation boosts antibody-antigen interactions to detect colorectal cancer

Researchers often use antibodies to detect specific molecules or biological markers, as they are remarkably precise at recognizing their targets.

25 Sep 2026

Blood proteins may help monitor Alzheimer’s treatment response

Patients with early symptoms of Alzheimer's disease may be prescribed anti-amyloid therapy, which can help clear the sticky clumps of amyloid protein in the brain that characterize Alzheimer's.

25 Sep 2026

Mount Sinai researchers discover how Alzheimer's gene damages blood vessels

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

24 Sep 2026

Five research teams secure funding for frontotemporal dementia studies

The Kissick Family Foundation, in partnership with the Milken Institute Science Philanthropy's Accelerator for Research and Collaboration (SPARC), today announced five research teams selected to receive a total of $2.5 million through the third funding cycle of the Kissick Family Foundation Frontotemporal Dementia (FTD) Grant Program.

24 Sep 2026

Chronic stress and social support affect how cognitive abilities change with age

Chronic stress and perceived social support may play a role in how memory and thinking abilities change with age, according to a new study led by researchers at Wake Forest University School of Medicine.

24 Sep 2026

Lund University gets $19.4 million grant for Alzheimer’s blood test

Alzheimer’s researcher Sebastian Palmqvist has been awarded USD 19.4 million (SEK 190 million) from the US National Institutes of Health (NIH), through its National Institute on Aging (NIA).

24 Sep 2026

Frailty linked to greater cognitive impairment risk in men with chronic kidney disease

New research from the University of Colorado Anschutz Department of Medicine is shedding light on how women and men with chronic kidney disease (CKD) may fare differently as they age and their disease progresses.

23 Sep 2026

Transient ischemic attacks linked to increased long-term dementia risk

Having a transient ischemic attack (TIA) is associated with an increased risk of developing dementia, according to a new study published September 23, 2026, in Neurology, the medical journal of the American Academy of Neurology.

23 Sep 2026

PsychAD studies map molecular mechanisms across major brain disorders

Research led by Mount Sinai scientists within the PsychAD Consortium, a large-scale, multidisciplinary initiative launched in 2019 with support from the National Institute on Aging (NIA), is featured in a landmark collection of nine papers published across the Nature family of journals that maps the molecular mechanisms underlying Alzheimer's disease, Parkinson's disease, schizophrenia, and other brain disorders.

23 Sep 2026

Menopause leaves a blood protein signature linked to brain aging and Alzheimer’s risk

Researchers identified a 16-protein blood signature associated with menopause that tracked more strongly with reproductive hormones than chronological age and was largely replicated in an independent UK Biobank cohort. Higher menopause proteomic scores were also associated with less favorable proteomic aging estimates and poorer cognitive outcomes in older women, including incident Alzheimer’s dementia, although the observational evidence does not establish causality.

23 Sep 2026