Alzheimer's & Dementia

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

GLP-1 Receptor Agonists in Alzheimer’s Disease: Emerging Off-Label Neuroprotective Potential

GLP-1 receptor agonists show strong preclinical neuroprotective potential in Alzheimer’s disease through effects on insulin signaling, neuroinflammation, amyloid, tau, and brain metabolism. Human evidence remains mixed, with observational studies suggesting lower dementia risk but randomized trials yet to demonstrate a clinically meaningful disease-modifying benefit.

Bright Light Therapy and Dementia

Inflammation and Alzheimer's Disease

Omega-3 and Alzheimer’s Disease

Transcutaneous Electrical Nerve Stimulation for Dementia

Alzheimer's Disease and the Microbiome

Alzheimer's Disease Questions

Dementia Treatment

Aromatherapy for Dementia

AAM - Genetics of Alzheimer's

Mixed Dementia Symptoms and Diagnosis

Types of Alzheimer's Disease

See more featured articles »

Dementia Symptoms

Differences Between Alzheimer's and Dementia

Alzheimer's Disease Epidemiology

Biomarkers for Alzheimer's Disease

Dementia Diagnosis

Alzheimer's Disease Causes

Stress and Alzheimer's Disease

Alzheimer's Disease and Sleep Disruption

Can Statins Protect Against Alzheimer’s Disease?

Childhood Dementia Signs and Symptoms

Alzheimer's Disease Prevention

What is Mixed Dementia?

What Causes Dementia?

Alzheimer's Disease Symptoms

Stem Cell Therapy for Alzheimer's

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Coconut Oil and Dementia

Integrated PET/MR for Alzheimer’s Disease

Can Happiness Protect You from Dementia?

Does Herpesvirus Cause Alzheimer's?

What are Amyloid Plaques?

Does Depression and Anxiety Increase the Risk of Dementia?

Alzheimer’s Disease | Definition, Causes, Diagnosis & Treatment

Alzheimer's Disease Diagnosis

AAM - The Search for a Cure to Alzheimer's

Alzheimer’s Disease and Calcium Supplements

What is Dementia?

Designing Dementia-Friendly Environments

Dancing Through Dementia: How Movement Aids Memory and Mood

Antibody Research and Alzheimer’s Disease

Alzheimer's and Veganism

Alzheimer’s Disease and Gingko Biloba

Dementia with Lewy Bodies

Amyloid Cascade Hypothesis

Alzheimer's Disease Treatments

Gender and Alzheimer’s Risk

Migraines and Dementia

Alzheimer’s tangles and plaques: what’s the difference?

Childhood Dementia Causes

Pollution and Alzheimer's

Mythbusting: Misconceptions in Dementia

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Diet and Alzheimer's Disease

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Antidepressants and Dementia: Is There a Link?

Is Alzheimer's Disease Transmissible?

AAM - Air pollution and Alzheimer's

Dementia Prevention

Mixed Dementia Prevention and Treatment

Latest Alzheimer's & Dementia News and Research

Neural networks reveal how training shapes learning in living brains

A new study has used a type of machine learning called a neural network to reveal how different kinds of training can change how learning happens-both in machines, and in living brains.

3 Sep 2026

Menopause may start changing the gut years before periods stop

A longitudinal study of 964 women found that blood markers of gut epithelial barrier dysfunction and microbial product translocation began to rise around 2 to 2.5 years before the final menstrual period and remained elevated after menopause. The findings suggest that changes in gut barrier integrity may form part of the biological transition through menopause and could help explain links between menopause, inflammation, and later health outcomes.

2 Sep 2026

New research visualizes how aerobic exercise alters brain activity patterns

Researchers at AIST, in collaboration with the University of Texas Southwestern Medical Center in the United States, examined changes in brain activity during cognitive tasks before and after acute aerobic exercise in young and older healthy adults.

2 Sep 2026

AI platform uncovers new molecular targets for Alzheimer's disease

Groundbreaking study published in Alzheimer's & Dementia reveals the crucial links between the NAD⁺-mitophagy axis and neurodegeneration.

1 Sep 2026

Aerobic exercise boosts executive function in postmenopausal women

Regular aerobic exercise – the kind that gets your heart pumping – can improve important thinking skills called executive functions, and the benefits appear especially strong for women after menopause, according to Rutgers researchers.

31 Aug 2026

Blood pressure intervention lowers dementia risk in community-based trial

In a community-based trial in rural China, an intensive blood-pressure lowering intervention reduced the incidence of dementia compared with usual care, according to results from the China Rural Hypertension Control Program presented in a Hot Line session today at ESC Congress 2026.

30 Aug 2026

Does a psychedelic need an awake brain to have lasting effects? This mouse study offers a clue

A single dose of psilocybin produced a lasting increase in sociability for at least two weeks in Cntnap2-knockout mice with social deficits, while it did not enhance sociability overall in mice with normal social behavior. The effect required 5-HT2A receptor activation and persisted when psilocybin was administered under light anesthesia, suggesting that wakefulness during the drug’s acute effects was not necessary for this behavioral response.

30 Aug 2026

Starting statins early after diabetes diagnosis linked to lower dementia risk

Early initiation of statins after diagnosis of type 2 diabetes was associated with a lower risk of dementia, according to a study presented today at ESC Congress 2026 and published in The Lancet Regional Health – Europe.

30 Aug 2026

People with diabetes may have another reason to protect their cardiovascular health

Better cardiovascular health, measured using Life’s Essential 8, was associated with a lower risk of mild cognitive impairment among people with diabetes after accounting for genetic susceptibility. Associations with dementia varied by genetic risk, while higher LE8 scores were also linked to greater gray matter volume and lower white matter hyperintensity volume.

30 Aug 2026

Atorvastatin reduces major cardiovascular events but misses disability-free survival goal

Atorvastatin reduced major cardiovascular events by 30% in older people without known cardiovascular disease, diabetes or dementia, but did not significantly improve disability-free survival, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

29 Aug 2026

Primate-specific DNA change reveals a new link to dementia-related neurodegeneration

Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the human and animal genomes have raised concerns that some disease mechanisms may not be fully explained by conventional animal models.

29 Aug 2026

Blood-brain barrier-crossing blood pressure drugs linked to lower dementia risk

In a large Australian cohort of adults with hypertension, use of blood-brain barrier-crossing antihypertensive medications was associated with a lower risk of dementia and mortality than use of non-crossing drugs. The association was strongest for beta-blockers and angiotensin II receptor blockers, although the observational design means the findings cannot establish causality.

27 Aug 2026

Parkinson’s disease imposes €22.8 billion economic burden across Europe

The annual societal cost of Parkinson's disease across Europe reached €22.8 billion in 2019, equivalent to €28.8 billion at 2025 prices, a new study published today in Movement Disorders has shown.

27 Aug 2026

Study links later-life food insecurity to elevated dementia risk

Older adults who experienced food insecurity in both midlife and later life had nearly four times the risk of probable dementia as those who remained food secure, according to new University of Michigan research.

27 Aug 2026

HRT linked to lower dementia risk, but timing and menopause type matter

In a UK Biobank study of 183,450 postmenopausal women followed for an average of 13.3 years, hormone replacement therapy use was associated with a modestly lower risk of dementia, with stronger associations in women who had surgical menopause or shorter natural estrogen exposure. The relationship also varied by age at HRT initiation, while the observational design means the findings cannot establish that HRT prevents dementia.

27 Aug 2026

Salk researchers isolate specific neurons controlling complex social behaviors

Our brains constantly integrate information about both our internal state and our surroundings to determine how we behave.

27 Aug 2026

Egg yolk peptides protect brain cells from oxidative stress

As the human lifespan increases, so too does the risk of developing neurological disorders such as Parkinson's disease, Alzheimer's disease, anxiety and depression.

27 Aug 2026

Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration

Brain diseases, including dementia, have long been studied using experimental animals such as mice.

27 Aug 2026

Multi-ancestry genetic score improves risk prediction for Alzheimer's disease

Late-onset Alzheimer disease (AD) is a progressive disorder characterized by cognitive decline and memory impairment, affecting an estimated 6.9 million people in the U.S.

27 Aug 2026

Brain shrinkage biomarker may predict early-onset Alzheimer’s progression

In people diagnosed with early-onset Alzheimer's disease, a biomarker tool that detects shrinkage of the brain's gray matter may predict how quickly someone may progress from mild cognitive impairment (MCI) to dementia, according to a new study published August 26, 2026, in Neurology, an official journal of the American Academy of Neurology.

27 Aug 2026