Alzheimer's & Dementia

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

GLP-1 Receptor Agonists in Alzheimer’s Disease: Emerging Off-Label Neuroprotective Potential

GLP-1 receptor agonists show strong preclinical neuroprotective potential in Alzheimer’s disease through effects on insulin signaling, neuroinflammation, amyloid, tau, and brain metabolism. Human evidence remains mixed, with observational studies suggesting lower dementia risk but randomized trials yet to demonstrate a clinically meaningful disease-modifying benefit.

AAM - Air pollution and Alzheimer's

Does Depression and Anxiety Increase the Risk of Dementia?

Alzheimer’s Disease | Definition, Causes, Diagnosis & Treatment

Alzheimer's Disease Diagnosis

Mythbusting: Misconceptions in Dementia

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Dementia with Lewy Bodies

Dementia Prevention

What is Mixed Dementia?

Differences Between Alzheimer's and Dementia

See more featured articles »

What are Amyloid Plaques?

Types of Alzheimer's Disease

Alzheimer's Disease Causes

Mixed Dementia Symptoms and Diagnosis

Alzheimer's Disease Symptoms

Coconut Oil and Dementia

AAM - The Search for a Cure to Alzheimer's

Omega-3 and Alzheimer’s Disease

Can Statins Protect Against Alzheimer’s Disease?

Is Alzheimer's Disease Transmissible?

Childhood Dementia Causes

Alzheimer’s Disease and Calcium Supplements

Dementia Diagnosis

Transcutaneous Electrical Nerve Stimulation for Dementia

Can Happiness Protect You from Dementia?

Designing Dementia-Friendly Environments

Biomarkers for Alzheimer's Disease

Pollution and Alzheimer's

Amyloid Cascade Hypothesis

Bright Light Therapy and Dementia

Antidepressants and Dementia: Is There a Link?

Inflammation and Alzheimer's Disease

Alzheimer's and Veganism

Dancing Through Dementia: How Movement Aids Memory and Mood

Alzheimer’s tangles and plaques: what’s the difference?

Alzheimer's Disease Prevention

Stem Cell Therapy for Alzheimer's

Antibody Research and Alzheimer’s Disease

Childhood Dementia Signs and Symptoms

Dementia Treatment

Alzheimer's Disease and the Microbiome

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Alzheimer's Disease Treatments

What is Dementia?

Alzheimer's Disease Epidemiology

Dementia Symptoms

Integrated PET/MR for Alzheimer’s Disease

Does Herpesvirus Cause Alzheimer's?

Alzheimer’s Disease and Gingko Biloba

Gender and Alzheimer’s Risk

Alzheimer's Disease and Sleep Disruption

Does Type 2 Diabetes Increase the Risk of Alzheimer’s Disease?

Stress and Alzheimer's Disease

Aromatherapy for Dementia

Diet and Alzheimer's Disease

Migraines and Dementia

What Causes Dementia?

Alzheimer's Disease Questions

AAM - Genetics of Alzheimer's

Mixed Dementia Prevention and Treatment

Latest Alzheimer's & Dementia News and Research

Graded physical activity prescriptions improve functional outcomes in psychiatry

Most of us have heard the advice so often that it has worn smooth, like a stone in a river: get some exercise. A new peer-reviewed Viewpoint in Brain Health, drawing on randomized trials, meta-analyses, and cohort studies, argues that this familiar sentence has been doing the wrong job.

5 Nov 2026

Modified zinc finger scaffold suppresses microglial activation in mouse brain

A KAIST-led research team has found that a protein involved in gene regulation can suppress the harmful aggregation of amyloid-beta, a peptide associated with Alzheimer's disease. The approach also reduced the toxicity of protein aggregates that had already formed.

5 Nov 2026

New tool identifies older adults at risk of delirium and falls from anticholinergic medications

Researchers funded by Health Data Research UK (HDR UK) have developed a new tool to help doctors and pharmacists identify older patients at risk of delirium and serious falls associated with taking multiple anticholinergic medications.

5 Nov 2026

Tau spreads more rapidly in early-onset Alzheimer's disease

Patients with early-onset Alzheimer's disease, whose symptoms start before age 65, have more extensive deposits of tau, a hallmark protein of the condition, compared with patients whose symptoms start at 65-plus, a new study found.

5 Nov 2026

Brain scans reveal clues to Alzheimer's risk years before memory loss begins

Inside the brains of some cognitively normal adults, firing patterns were able to foretell Alzheimer's disease years before the onset of memory loss or the accumulation of plaques and tangles, according to new Stanford Medicine-led research.

5 Nov 2026

Targeting brain protein may help treat MEF2C-related neurological disorders

A particular signaling protein in the brain could be a therapeutic target for neurological disorders arising from the deletion of the autism-linked gene MEF2C, University of Illinois Urbana-Champaign researchers found in a new mouse study.

4 Nov 2026

Longer reproductive lifespan and hormonal history may influence brain vascular health

A longer reproductive lifespan and a history of using birth control pills or menopausal hormone therapy were associated with certain signs of blood vessel health in the brain, according to a study published November 4, 2026, in Neurology, the medical journal of the American Academy of Neurology.

4 Nov 2026

Caffeine intake rises among Korean adults as brewed coffee gains ground

An analysis of 48,991 Korean adults found that average daily caffeine intake from beverages increased between 2016 and 2024, while the odds of consuming at least 400 mg of caffeine on a single day rose by approximately 5% annually. Coffee remained the predominant caffeine source, with a shift from prepared coffee mixes toward brewed coffee and distinct consumption patterns across age groups and sexes.

4 Nov 2026

Exercise may improve mood and memory, and researchers say doctors should prescribe it

In a Viewpoint, researchers examined evidence that exercise can reduce symptoms of depression and anxiety, support cognition, and may help lower the risk of cognitive decline, although evidence for dementia prevention remains largely observational. The authors argue that exercise should be prescribed as a structured component of brain-health care, with individualized recommendations that account for medical conditions, safety, and barriers to participation.

4 Nov 2026

Novel treatment clears dementia-linked proteins from the waking brain

The brain's own clearance mechanisms are most active during sleep. Researchers have now shown that this natural clearance process can also be enhanced while people are awake.

4 Nov 2026

Good sleep protects brain health in people with cardiometabolic disease

People with type 2 diabetes, heart disease or stroke who sleep well have better cognitive function and greater brain volume than people with the same conditions who sleep poorly, according to a new study from Karolinska Institutet.

4 Nov 2026

Eating peanuts every day may change your brains insulin response

The study finds that unsalted peanuts may enhance brain insulin responsiveness, providing new insights into dietary influences on cognitive health in aging.

4 Nov 2026

Genetic family mapping uncovers hidden links across ALS and FTD

Researchers at the Macquarie University Brain Institute and Clinic have helped accelerate the search for disease-causing genes by building new genetic 'families'.

3 Nov 2026

Memory problems may matter more than slower thinking for dementia risk in frail adults

In a study of 7,023 adults in England, researchers identified three cognitive frailty profiles with different patterns of memory, executive function, and processing speed impairment. Over approximately 10 years, profiles involving memory impairment were associated with higher odds of subsequent dementia, while socioeconomic, educational, and psychosocial factors showed different associations across the three groups.

3 Nov 2026

Heart disease and depression may affect brain aging in an unexpected way

A longitudinal study of 5,423 adults in England found that cardiovascular disease was associated with faster cognitive decline, with the strongest association observed among participants with consistently low depressive symptoms. Those with persistent moderate or high depressive symptoms generally experienced poorer cognitive performance and faster overall deterioration, despite showing a weaker additional association between cardiovascular disease and cognitive decline.

3 Nov 2026

Private equity hospice buyouts drive up Medicare spending

A study of for-profit hospices acquired by private equity firms found that Medicare spending rose by 5.9 percent per hospice stay after acquisition, compared with similar for-profit hospices that weren't acquired.

3 Nov 2026

New dementia risk tool designed for the countries that need it most

An international team led by Northumbria University has developed and validated a simple five-factor risk score to identify older people at elevated risk of dementia in low- and middle-income countries (LMICs) - where around 60% of the world's dementia cases now occur.

3 Nov 2026

Study identifies molecular links between menopause and brain aging

Researchers at UC Santa Barbara, UC San Francisco and international collaborators are uncovering the cascade of molecular events that happen when women undergo menopause, a time of life marked by endocrine changes and symptoms like hot flashes, brain fog and sleep disturbances.

2 Nov 2026

Long-term study supports cardiovascular safety of contemporary hormone replacement therapy

Contemporary hormone replacement therapy (HRT) was not associated with an increased risk for heart attack, stroke, blood clots or death among women ages 45 to 59, according to a large, long-term study of over 52,000 women in Israel.

2 Nov 2026

Scientists may have underestimated how much genes contribute to Alzheimer's risk

A large multi-ancestry genetic analysis identified 127 genomic loci associated with Alzheimer's disease, including 48 previously unreported loci, and implicated microglial and neuronal gene-expression patterns in disease susceptibility. The researchers estimated that common genetic variants account for 16% of Alzheimer's disease liability in European-ancestry populations, substantially higher than previous estimates, while demonstrating improved polygenic risk prediction that remained less reliable in non-European populations.

2 Nov 2026