Type 1 Diabetes

Type 1 diabetes, formerly called juvenile diabetes or insulin-dependent diabetes, is usually first diagnosed in children, teenagers, or young adults. In this form of diabetes, the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed them. Treatment for type 1 diabetes includes taking insulin shots or using an insulin pump, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 1 Diabetes?

Type 1 diabetes mellitus describes a condition where the body cannot produce insulin which leads to a very high level of blood sugar and associated complications. The condition, which usually develops in childhood or adolescence, affects millions of people worldwide.

Diabetes Mellitus Type 1 Pathophysiology

Diabetes Mellitus Type 1 Inheritance

Type 1 Diabetes Treatment

Type 1 Diabetes Cure

Type 1 Diabetes Prevention

Type 1 Diabetes Research

Does the 'Stomach Flu' Vaccine Prevent Type I Diabetes?

Latest Type 1 Diabetes News and Research

Diabetes drugs cut asthma attacks by up to 70%, reshaping treatment options

Metformin and GLP-1 receptor agonists significantly reduce asthma attacks in patients with type 2 diabetes, offering potential new treatments for asthma.

19 Nov 2024

Research links self-efficacy to better diabetes management in adolescents

Self-efficacy involves one's belief in their own ability to carry out tasks successfully. A psychological construct studied by psychologist Albert Bandura since the 1980s, it has been shown to have an influence not only on cognitive processes, but also on behavior and emotions.

7 Nov 2024

Anti-inflammatory cytokine linked to capillary obstruction and cognitive decline in diabetes

Elevated IL-10 in diabetes causes capillary obstruction, linked to cognitive deficits. Blocking IL-10 receptors shows promise for improving brain function.

7 Nov 2024

Genetic and environmental drivers shape early type 1 diabetes risk in children

Researchers from the TEDDY study highlight how specific genetic and environmental factors may drive early autoimmunity linked to type 1 diabetes in children, emphasizing distinct patterns for different autoantibodies.

5 Nov 2024

Rise in weight-management glucose-lowering drug prescriptions in type 1 diabetes patients

From 2010 to 2023, GLP-1RAs and SGLT2 inhibitors saw rising prescriptions in type 1 diabetes, particularly for patients with obesity and cardiorenal risks.

23 Oct 2024

COVID-19 raises the risk of type 2 diabetes in children, study reveals

Researchers found that children who contracted COVID-19 were at a higher risk of developing type 2 diabetes within six months, compared to those with other respiratory infections.

15 Oct 2024

How Minnesota figures into the presidential politics of insulin prices

In June 2019, Lija Greenseid handed Minnesota Gov. Tim Walz an empty vial of insulin that her 13-year-old daughter had painted gold.

1 Oct 2024

New treatment strategy targets somatostatin to prevent blood sugar drops in type 1 diabetes

Inhibiting the hormone somatostatin may be a new treatment strategy to prevent dangerous blood glucose drops in type 1 diabetes.

30 Sep 2024

Autoimmune diseases more common in women who stop ovulating before 40

The study finds a significant correlation between premature ovarian insufficiency and autoimmune diseases, urging further investigation into prevention methods.

30 Sep 2024

Why hypoglycemia-induced glucagon secretion becomes impaired in diabetes

Findings indicate that excessive somatostatin inhibits glucagon secretion in type 1 diabetes, offering a novel target for hypoglycemia management strategies.

27 Sep 2024

IBD increases type 1 diabetes risk, revealing a bidirectional link between the two conditions

Researchers discovered that IBD significantly increases the risk of developing T1D, and this association works both ways, independent of genetics and familial factors. The strongest link was seen in ulcerative colitis patients.

19 Sep 2024

The importance of mitochondrial function in health and disease

The World Mitochondria Society (WMS) is preparing for its annual Targeting Mitochondria 2024 conference, which will focus on innovative strategies to "charge" cells by supplying them with extra mitochondria to enhance cellular function and combat diseases.

18 Sep 2024

Large-scale study to explore impact of type 1 diabetes on brain development in children

About half of adults with type 1 diabetes face significant cognitive impairment, including problems with working memory and executive function that affect day-to-day thinking. But less is known about how the condition affects children during a window of time known to be critical for healthy brain development.

17 Sep 2024

Common diabetes medication slows growth of precancerous esophageal cells, study shows

A common diabetes medication, metformin, slows the growth of precancerous cells in the oesophagus while some metabolic conditions accelerate it, suggests a new study.

16 Sep 2024

Study reveals how SARS-CoV-2 triggers diabetes by destroying pancreatic cells

Researchers from Weill Cornell Medicine have used a cutting-edge model system to uncover the mechanism by which SARS-CoV-2, the virus that causes COVID-19, induces new cases of diabetes, and worsens complications in people who already have it.

13 Sep 2024

Semaglutide and tirzepatide significantly improve weight loss and glycemic control in type 1 diabetes

Semaglutide and tirzepatide treatment lead to significant weight loss and improve blood sugar control in individuals with type 1 diabetes (T1D) who are living with overweight or obesity, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September) has found.

13 Sep 2024

Advanced insulin pump technology improves diabetes management for marathon runners

A series of case reports to be presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept), describe how a technology giving insulin doses informed by an insulin pump algorithm helped three adults with type 1 diabetes better manage their blood sugars enabling them to lead more active lives, and even run marathons.

13 Sep 2024

Fear of hypoglycemia limits physical activity in adults with type 1 diabetes

Despite high use of continuous glucose monitoring and insulin pump therapy, fear of hypoglycemia (low blood sugar) remains a significant barrier to physical activity and exercise for adults with type 1 diabetes (T1D), according to new research to be presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept).

12 Sep 2024

Reduced heart rate variability linked to higher mortality in people with diabetes

Disruption to normal variations in daily heart rate (HR) is associated with a much higher risk of dying in people with type 1 and type 2 diabetes over 21 years, according to new research to be presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept).

9 Sep 2024

Eating fruit, oats and rye in childhood may increase type 1 diabetes risk

New research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September), shows that eating fruit, oats and rye in childhood is associated with a higher risk of developing type 1 diabetes (T1D).

9 Sep 2024