Type 1 Diabetes

Type 1 diabetes, formerly called juvenile diabetes or insulin-dependent diabetes, is usually first diagnosed in children, teenagers, or young adults. In this form of diabetes, the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed them. Treatment for type 1 diabetes includes taking insulin shots or using an insulin pump, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 1 Diabetes?

Type 1 diabetes mellitus describes a condition where the body cannot produce insulin which leads to a very high level of blood sugar and associated complications. The condition, which usually develops in childhood or adolescence, affects millions of people worldwide.

Diabetes Mellitus Type 1 Pathophysiology

Diabetes Mellitus Type 1 Inheritance

Type 1 Diabetes Treatment

Type 1 Diabetes Cure

Type 1 Diabetes Prevention

Type 1 Diabetes Research

Does the 'Stomach Flu' Vaccine Prevent Type I Diabetes?

Latest Type 1 Diabetes News and Research

COVID-derived molecular mimics may be involved in triggering autoimmunity

COVID infection has been linked to higher risk of autoimmune disorders, including rheumatoid arthritis and type 1 diabetes.

26 Mar 2025

Early antibiotic exposure may boost risk of diabetes later in life

Exposure to antibiotics during a key developmental window in infancy can stunt the growth of insulin-producing cells in the pancreas and may boost risk of diabetes later in life, new research in mice suggests.

25 Mar 2025

Healthcare professionals need better support to recognize T1DE

Healthcare professionals need better support to help recognize and treat symptoms of disordered eating in people living with type 1 Diabetes, according to new research from the University of Surrey.

20 Mar 2025

Clinical trial investigates osteoporosis medication for type 1 diabetes

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States and a top research center for diabetes and other life-threatening illnesses, is leading a phase 1/2 clinical trial investigating an osteoporosis medication as a way to improve beta cell health in people with early type 1 diabetes.

19 Mar 2025

Keto controversy? Experts say it’s here to stay

Low-carb and ketogenic diets offer sustainable solutions for chronic disease, enhancing metabolic health and supporting weight loss through dietary changes.

18 Mar 2025

New insights into screening and treatment for diabetic retinal disease

Diabetes affects more than 1 in 10 adults worldwide and has been accompanied by an increase in vision-threatening diabetic retinal disease.

12 Mar 2025

Could a keto diet replace diabetes meds? New research explores the possibilities

A review published in Nutrients finds that ketogenic diets (KD) may offer superior benefits for weight loss, blood sugar control, and inflammation compared to other diets. Researchers also highlight potential mental health improvements but call for more clinical trials.

11 Mar 2025

Automated insulin delivery systems are safe and effective for older adults with type 1 diabetes

New research from Washington State University in collaboration with five other institutions suggests that automated insulin delivery (AID) systems are safe and effective for use by older adults with type 1 diabetes.

11 Mar 2025

New research links early-life microbes to long-term metabolic health

The microbiome shapes development of insulin-producing cells in infancy, leading to long-term changes in metabolism and diabetes risk, new research in mice has found.

6 Mar 2025

Republicans once wanted government out of health care. Trump voters see it differently.

Like many Americans who voted for Donald Trump, Jason Rouse hopes the president's return will mean lower prices for gas, groceries, and other essentials.

27 Feb 2025

Machine learning algorithm decodes immune system’s hidden data for disease detection

Your immune system harbors a lifetime's worth of information about threats it's encountered - a biological Rolodex of baddies.

24 Feb 2025

Telehealth and primary care providers deliver effective diabetes treatment

Researchers at The University of Colorado Anschutz Medical Campus and colleagues at Massachusetts General Hospital, have found that people with diabetes can achieve the same positive results using advanced insulin technology when trained by their primary care providers (PCPs) or through telehealth as they would by seeing a specialist in person.

24 Feb 2025

Engineered blood vessel cells boost islet transplant success in diabetes treatment

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells and reversed diabetes in a preclinical study led by Weill Cornell Medicine investigators.

21 Feb 2025

How does intermittent fasting affect β cell function and diabetes risk

Research shows short-term fasting improves glucose regulation, while long-term fasting in young mice impairs β cell function, potentially increasing T1D risk.

18 Feb 2025

Intermittent fasting may harm insulin-producing cells in teens

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers from Technical University of Munich (TUM), LMU Hospital Munich, and Helmholtz Munich discovered that chronic intermittent fasting disrupted the development of insulin-producing beta cells in young mice.

14 Feb 2025

Hybrid closed-loop insulin pumps improve time in range, but increase ketoacidosis

People with type 1 diabetes require continuous insulin treatment and must regularly measure their glucose levels. With open-loop therapies*, insulin administration is manually controlled, while hybrid closed-loop systems* automatically regulate insulin delivery.

13 Feb 2025

Type 1 diabetes patients face lower cardiovascular risk than Type 2 diabetes

A new study published in JSCAI has revealed a lower risk of cardiovascular events for patients with Type 1 diabetes (often called juvenile diabetes) compared to those with Type 2 diabetes.

12 Feb 2025

UVA launches trial to test AI-powered device for diabetes management

For people living with Type 1 Diabetes (T1D), keeping blood sugar levels in check is a constant challenge.

11 Feb 2025

Comprehensive atlas of endothelial cells advances diabetes research

The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas have been notoriously difficult to study, but Weill Cornell Medicine investigators have now succeeded in comprehensively detailing the unique characteristics of these cells.

7 Feb 2025

SAB BIO announces positive topline Phase 1 clinical results with potentially disease-modifying T1D therapy SAB-142

SAB BIO, (“SAB BIO”), a clinical-stage biopharmaceutical company with a novel immunotherapy platform that is developing human anti-thymocyte immunoglobulin (hIgG) for delaying the onset or progression of type 1 diabetes (T1D), today announced positive topline data from a Phase 1 trial of SAB-142 in a single-ascending dose among healthy volunteers.

From SAb Biotherapeutics, Inc. 6 Feb 2025