Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

Gastroschisis Causes

Gut Microbiota

The Microbiome and Aging

Gut-on-a-Chip to Model Coeliac Disease

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Short-Chain Fatty Acids (SCFAs)

What is Ulcerative Colitis?

Dysbiosis and the Microbiome

Gastroparesis Treatments

Irritable Bowel Syndrome (IBS) Food Triggers

Irritable Bowel Syndrome (IBS) and Exercise

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Risk Factors for Small Intestinal Bacterial Overgrowth

Gastrointestinal Bleeding Symptoms

How to Recover Gut Health After Clostridium difficile Infection

Irritable Bowel Syndrome (IBS) Psychological Therapies

Human Microbiome

Causes of Gastro-Esophageal Reflux Disease (GERD)

Gastritis Treatments

Gastroparesis Symptoms

Fermented Foods and Gut Health

Treatment of Gastric Varices

What is Gastrointestinal Bleeding?

What is a Gastric Bypass?

Post-Infectious Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) and Diet

Microbiome and Disease

Celiac Disease Treatment

Skin Microbiota

Parkinson's Disease and the Gut Microbiome

Irritable Bowel Syndrome (IBS) Differential Diagnosis

Gastroparesis Epidemiology

Genetics of Inflammatory Bowel Disease (IBD)

Fecal Microbiota Transplant

Irritable Bowel Syndrome (IBS) Prognosis

Effects of a Gluten-Free Diet on the Gut Microbiota

What is Gastroenterology?

Irritable Bowel Syndrome (IBS) Epidemiology

Types of Gastrectomy

Diabetic Gastroparesis

What is Gastroschisis?

Gastroparesis and Diet

Human Microbiome Project (HMP)

Do Serotonin and Antidepressants Affect the Microbiome?

FODMAPs and Irritable Bowel Syndrome (IBS)

Microbiome and Cancer

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Is There a Link Between Migraine and the Gut Microbiome?

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Antibiotics and the Microbiome

Diagnosis of Irritable Bowel Syndrome

Celiac Disease Screening

Gastric Bypass Complications

Probiotics and IBS

What is Vaginal Microbiome?

Gastric Varices - Signs and Symptoms

Celiac Disease Pathogenesis

Gastroschisis Prognosis

Fecal Microbiota Transplant Regulation

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Celiac Disease Diagnosis

Irritable Bowel Syndrome (IBS) Comorbidities

Irritable Bowel Syndrome (IBS) and Stress Response

Symptoms of Irritable Bowel Syndrome

Gastrointestinal Stromal Tumor (GIST) Treatment

Inflammatory Bowel Disease (IBD) in Pregnancy

Dermatitis Herpetiformis and Celiac Disease

Malrotation of the Gastrointestinal Tract

What is Irritable Bowel Syndrome?

Gastritis Symptoms

FODMAP Research

Is Dermatitis Herpetiformis Caused by Herpes?

Fecal Microbiota Transplant Technique

Gastric Varices

Conjunctiva microbiota

High FODMAP Foods and Low FODMAP Food Alternatives

Symptoms and Diagnosis of Intestinal Malrotation

Gastrointestinal Stromal Tumor (GIST) Causes

Celiac Disease Symptoms

What is Gastroparesis?

Ulcerative Colitis Causes

After Gastric Bypass Surgery

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

Genetic Factors that Influence Bacterial Diversity in the Human Gut

What does Sleeve Gastrectomy Involve?

How Does the Diet Impact Microbiota?

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Irritable Bowel Syndrome (IBS) and Fibromyalgia

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Treatment of Irritable Bowel Syndrome

Gastric Bypass Criteria

Gastric Bypass Benefits

Does Wheat Cause Gut Inflammation?

Mesentery: a new organ?

Oral Microbiota

Drug Metabolism and Microbiome

Gastroparesis Diagnosis

What is Celiac Disease?

Irritable Bowel Syndrome (IBS) Research

What is Gluten?

Gastric Carcinoma

Gastric Bypass Types

Mechanism of Irritable Bowel Syndrome (IBS)

Inflammatory Bowel Disease and Colorectal Cancer

Crohn's Disease Cause

Causes of Irritable Bowel Syndrome

Dysbiosis and Aging

Disease Susceptibility and the Microbiome

Gastroparesis Causes

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

Does the Microbiome Interact with the Human Endocrine System?

Gastritis Diagnosis

Microbiome-Host Cell Interactions

Irritable Bowel Syndrome (IBS) and Infections

Achievements of the Human Microbiome Project

Gastrointestinal Disease and Skin Problems

What is Gastroenteritis?

Alzheimer's Disease and the Microbiome

Self-Help for Irritable Bowel Syndrome (IBS)

Sarin Classification of Gastric Varices

Gastritis Causes

What is Gastritis?

Gastrointestinal Stromal Tumor Pathogenesis

Gastrointestinal Bleeding Treatment

Low FODMAP Diet

Treatment and Prognosis for Intestinal Malrotation

Latest Gastrointestinal Health News and Research

Why Salmonella Dublin poses a food safety threat in beef and dairy

The study on Salmonella Dublin highlights its genomic similarities and resistance traits, raising concerns for food safety and antimicrobial resistance.

27 Aug 2025

Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure

Chronic liver cirrhosis (LC) and acute-on-chronic liver failure (ACLF) are interconnected hepatic disorders associated with substantial morbidity and mortality.

27 Aug 2025

Groundbreaking method captures microbial memory at the earliest stages of colony growth

Bacteria aren't just mindless microbes. New research from the Hebrew University of Jerusalem reveals that single bacterial cells can carry a "memory" of their past environments-passing it down through generations-before eventually forgetting.

26 Aug 2025

Family history of liver disease significantly raises risk of severe alcohol-related hepatitis

In a groundbreaking study, research scientists from the Indiana University School of Medicine and Regenstrief Institute found that individuals with a parent who died from liver disease face more than double the risk of developing alcohol-associated hepatitis, one of the deadliest forms of alcohol-related liver disease, compared with similar heavy drinkers without that family history.

26 Aug 2025

Probiotics limit the spread of drug-resistant genes in preemies

Study reveals probiotics help preterm infants develop healthier gut microbiomes, reducing multidrug-resistant bacteria and enhancing neonatal care outcomes.

26 Aug 2025

Antibiotics in pregnancy and infancy do not raise autoimmune disease risk in children

A nationwide Korean cohort study found that antibiotic use during pregnancy or early infancy did not increase overall risk of childhood autoimmune diseases. Subgroup signals for Crohn’s disease and autoimmune thyroiditis warrant cautious follow-up.

25 Aug 2025

Shame linked to lower quality of life in people with gut disorders

Feelings of shame are linked to reduced quality of life - as shown by the first study to measure shame as a factor influencing the connection between chronic gastrointestinal disorders and mental health.

25 Aug 2025

iconPCR™: Powering the next wave of metagenomics and microbiome discovery

The landscape of metagenomics and microbiome research is evolving at breakneck speed. As sequencing technologies improve and the demand for high-resolution, bias-free microbial data grows, the bottleneck is shifting from sequencing itself to the quality of upstream sample preparation.

From n6 23 Aug 2025

n6™ announces strategic partnership with SeqCenter to deliver unmatched data quality in metagenomics

n6 is proud to announce a strategic partnership with SeqCenter, who is launching a groundbreaking full-length 16S sequencing service at FEMS Micro.

From n6 23 Aug 2025

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Researchers from Kyoto Prefectural University of Medicine and collaborating Japanese institutions found that patients carrying colibactin-producing Escherichia coli (pks+ E. coli) in their colon polyps were more than three times as likely to have a history of colorectal cancer compared to those without the bacterium.

22 Aug 2025

New method enables comprehensive analysis of metabolites in biological samples

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

Gut bacteria and insomnia influence each other in small but significant ways, study shows

Scientists used Mendelian randomisation to explore the two-way relationship between gut microbiota and insomnia, analyzing GWAS data from over 386,000 individuals and two major microbiome cohorts. The study found only limited taxa surviving strict correction, suggesting small but causal links that highlight the gut–brain axis in sleep health.

21 Aug 2025

Gut bacteria in mothers and newborns may shape infants’ risk of early respiratory infections

Finnish researchers found that differences in maternal and infant gut microbiota during the first weeks of life were linked to the risk of respiratory tract infections in the first six months. Specific bacteria, including butyrate producers and opportunistic pathogens, may shape early infection susceptibility.

21 Aug 2025

Breakthroughs in diagnosis and therapy for transthyretin amyloidosis

Transthyretin amyloidosis (ATTR) is caused by the misfolding and aggregation of the transthyretin (TTR) protein, leading to multi-organ damage.

21 Aug 2025

Elevated TMAO levels linked to higher risk of abdominal aortic aneurysms

Cleveland Clinic researchers have discovered a connection between elevated blood levels of TMAO (trimethylamine N-oxide) - a byproduct of gut bacteria digestion of nutrients found in red meat and other animal products - and a higher risk of abdominal aortic aneurysms.

20 Aug 2025

Low FODMAP diet increases GLP-1 and relieves IBS symptoms

This study reveals that a low FODMAP diet alleviates IBS symptoms and increases GLP-1 levels, suggesting new avenues for dietary interventions in gut health.

20 Aug 2025

Fasting supports type 1 diabetes care by reshaping the microbiome

A week of fasting alters the gut microbiome in type 1 diabetes, aligning it with healthy profiles and enhancing cholesterol and weight management.

20 Aug 2025

Physician retention in New York reaches highest level in nearly a decade

The percentage of physicians who go on to practice in New York State after completing their residency training continues to climb.

19 Aug 2025

Scientists link gut microbes to stronger muscles and healthier aging

Researchers discovered that gut microbes, including Lactobacillus reuteri and L. johnsonii, can enhance muscle strength in aging mice. Co-administration of these strains boosted muscle mass, performance, and reduced inflammation, pointing to a possible microbiome-based strategy for muscle health.

19 Aug 2025

Landmark robotic spine surgery advances pediatric orthopedic care at Ochsner Children’s

Ochsner Children's has achieved a major milestone by performing the first robotic-assisted pediatric spine deformity surgery in Louisiana and the Gulf South.

18 Aug 2025