Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

Irritable Bowel Syndrome (IBS) and Fibromyalgia

FODMAP Research

Gut-on-a-Chip to Model Coeliac Disease

Low FODMAP Diet

Gastric Varices - Signs and Symptoms

Gastric Varices

Microbiome and Disease

What is Gastroenteritis?

Oral Microbiota

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Treatment of Gastric Varices

See more featured articles »

Malrotation of the Gastrointestinal Tract

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Risk Factors for Small Intestinal Bacterial Overgrowth

Irritable Bowel Syndrome (IBS) Psychological Therapies

What is Gastritis?

Dermatitis Herpetiformis and Celiac Disease

Gastric Bypass Benefits

Gastroparesis Symptoms

Effects of a Gluten-Free Diet on the Gut Microbiota

Gastrointestinal Stromal Tumor (GIST) Causes

Post-Infectious Irritable Bowel Syndrome

Gastroparesis Epidemiology

Gastritis Treatments

Fecal Microbiota Transplant Technique

Gastrointestinal Stromal Tumor Pathogenesis

What does Sleeve Gastrectomy Involve?

Celiac Disease Screening

Gastric Bypass Types

Diagnosis of Irritable Bowel Syndrome

Celiac Disease Symptoms

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Irritable Bowel Syndrome (IBS) Comorbidities

What is a Gastric Bypass?

Human Microbiome

Does Wheat Cause Gut Inflammation?

Microbiome-Host Cell Interactions

The Microbiome and Aging

Gastritis Diagnosis

Do Serotonin and Antidepressants Affect the Microbiome?

Fecal Microbiota Transplant

Microbiome and Cancer

Genetics of Inflammatory Bowel Disease (IBD)

How Does the Diet Impact Microbiota?

Fermented Foods and Gut Health

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Diabetic Gastroparesis

Gastrointestinal Bleeding Treatment

Irritable Bowel Syndrome (IBS) and Infections

Gastric Bypass Criteria

Gastroparesis Treatments

What is Gastroschisis?

Drug Metabolism and Microbiome

Conjunctiva microbiota

Gastroparesis Diagnosis

Irritable Bowel Syndrome (IBS) Research

What is Ulcerative Colitis?

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Gastroschisis Causes

How to Recover Gut Health After Clostridium difficile Infection

Genetic Factors that Influence Bacterial Diversity in the Human Gut

High FODMAP Foods and Low FODMAP Food Alternatives

Disease Susceptibility and the Microbiome

Mechanism of Irritable Bowel Syndrome (IBS)

Gastrointestinal Stromal Tumor (GIST) Treatment

Inflammatory Bowel Disease and Colorectal Cancer

What is Gastroenterology?

What is Gastroparesis?

Treatment of Irritable Bowel Syndrome

Probiotics and IBS

FODMAPs and Irritable Bowel Syndrome (IBS)

Parkinson's Disease and the Gut Microbiome

Gastric Carcinoma

Does the Microbiome Interact with the Human Endocrine System?

Gut Microbiota

What is Gluten?

Treatment and Prognosis for Intestinal Malrotation

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Irritable Bowel Syndrome (IBS) Prognosis

What is Gastrointestinal Bleeding?

Types of Gastrectomy

Gastroparesis Causes

What is Celiac Disease?

Treatment of Gastro-Esophageal Reflux Disease (GERD)

What is Irritable Bowel Syndrome?

Gastritis Symptoms

Inflammatory Bowel Disease (IBD) in Pregnancy

Alzheimer's Disease and the Microbiome

Irritable Bowel Syndrome (IBS) and Exercise

Celiac Disease Treatment

Crohn's Disease Cause

Human Microbiome Project (HMP)

Skin Microbiota

Short-Chain Fatty Acids (SCFAs)

Gastrointestinal Disease and Skin Problems

Is There a Link Between Migraine and the Gut Microbiome?

Gastroschisis Prognosis

Irritable Bowel Syndrome (IBS) Food Triggers

Mesentery: a new organ?

Ulcerative Colitis Causes

Celiac Disease Diagnosis

Fecal Microbiota Transplant Regulation

Gastroparesis and Diet

Gastritis Causes

Irritable Bowel Syndrome (IBS) Differential Diagnosis

Causes of Gastro-Esophageal Reflux Disease (GERD)

Gastrointestinal Bleeding Symptoms

Celiac Disease Pathogenesis

Dysbiosis and the Microbiome

Irritable Bowel Syndrome (IBS) Epidemiology

Symptoms and Diagnosis of Intestinal Malrotation

Dysbiosis and Aging

Sarin Classification of Gastric Varices

Irritable Bowel Syndrome (IBS) and Stress Response

What is Vaginal Microbiome?

Symptoms of Irritable Bowel Syndrome

Self-Help for Irritable Bowel Syndrome (IBS)

Causes of Irritable Bowel Syndrome

Gastric Bypass Complications

Irritable Bowel Syndrome (IBS) and Diet

Antibiotics and the Microbiome

Achievements of the Human Microbiome Project

Is Dermatitis Herpetiformis Caused by Herpes?

After Gastric Bypass Surgery

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

Latest Gastrointestinal Health News and Research

AGA releases new clinical guideline for diagnosing and managing gastroparesis

The American Gastroenterological Association (AGA) has released a new clinical guideline with 12 conditional recommendations for diagnosing and managing gastroparesis, a serious and often debilitating disease.

19 Sep 2025

Massage Therapy Foundation funds CHOP study on pediatric irritable bowel syndrome

The Massage Therapy Foundation (MTF) announces the award of a research grant to Children's Hospital of Philadelphia (CHOP). The grant will support a three-year study entitled Myofascial Release Therapy in Irritable Bowel Syndrome led by Primary Investigators Maria Mascarenhas, MBBS and Alain J. Benitez, MD, MSTR.

18 Sep 2025

Oral microbiome linked to threefold higher pancreatic cancer risk

Twenty-seven species of bacteria and fungi among the hundreds that live in people's mouths have been collectively tied to a 3.5 times greater risk of developing pancreatic cancer, a study led by NYU Langone Health and its Perlmutter Cancer Center shows.

18 Sep 2025

Health care cuts threaten homegrown solutions to rural doctor shortages

Olivia Owlett chose to do her primary care residency in this Northern California college town largely because it faces many of the same health care challenges she grew up with.

18 Sep 2025

Holder vs Retort: How milk pasteurization shapes preterm infants’ gut health

Researchers at Vanderbilt University Medical Center found that pasteurization methods shape the gut microbiomes of preterm infants fed donor human milk. Holder pasteurization preserved microbial diversity and beneficial taxa better than Retort, producing microbiomes more similar to those from mothers’ own milk.

17 Sep 2025

New genetic test can help predict how people will respond to weight-loss medications

Mayo Clinic researchers have developed a genetic test that can help predict how people will respond to weight loss medications such as GLP-1s.

17 Sep 2025

Study reveals how ozone exerts multi-organ effects by disturbing the lung-liver connection

Ozone pollution is rising worldwide, frequently exceeding safety thresholds in urban centers and industrial regions. Its health risks are well-documented: breathing ozone can worsen asthma, damage airways, and increase the risk of cardiovascular and neurological disorders.

17 Sep 2025

Can changing food texture reduce how much we eat? Dutch study investigates

A new randomized controlled trial protocol from the Netherlands will test whether altering the texture, and thus the eating rate, of ultra-processed foods can reduce daily energy intake. The study will investigate how sensory properties, such as food hardness, affect metabolism, appetite, and microbiome composition.

16 Sep 2025

Personalized risk information does not increase colorectal cancer screening rates

A new Indiana University School of Medicine clinical trial - the largest of its kind to date - found that providing personalized colorectal cancer risk information to patients and their health care providers did not improve screening rates for the deadly ailment.

16 Sep 2025

Ketogenic diets may lower migraine frequency and medication use

This narrative review argues that the migraine brain is hypometabolic, with converging evidence of mitochondrial dysfunction, impaired glucose handling, neuroinflammation, microbiome shifts, and obesity-related pathways. It proposes ketogenic diets as a plausible preventive strategy that may reduce monthly migraine days and medication use, while emphasizing the need for larger, rigorous randomized trials and careful clinical oversight.

14 Sep 2025