Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

What is Ulcerative Colitis?

Irritable Bowel Syndrome (IBS) and Exercise

Gut Microbiota

Gastrointestinal Stromal Tumor (GIST) Causes

What is Gluten?

Treatment of Gastric Varices

Is There a Link Between Migraine and the Gut Microbiome?

What is Irritable Bowel Syndrome?

Gut-on-a-Chip to Model Coeliac Disease

Sarin Classification of Gastric Varices

Gastric Bypass Criteria

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Symptoms and Diagnosis of Intestinal Malrotation

Genetic Factors that Influence Bacterial Diversity in the Human Gut

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Celiac Disease Treatment

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Irritable Bowel Syndrome (IBS) Psychological Therapies

What is Gastroschisis?

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

Gastroparesis Symptoms

How to Recover Gut Health After Clostridium difficile Infection

Celiac Disease Screening

Does Wheat Cause Gut Inflammation?

Gastrointestinal Stromal Tumor Pathogenesis

Irritable Bowel Syndrome (IBS) Comorbidities

Mechanism of Irritable Bowel Syndrome (IBS)

Gastroschisis Causes

After Gastric Bypass Surgery

Irritable Bowel Syndrome (IBS) Research

Low FODMAP Diet

Gastrointestinal Bleeding Symptoms

Diagnosis of Irritable Bowel Syndrome

Malrotation of the Gastrointestinal Tract

Does the Microbiome Interact with the Human Endocrine System?

Irritable Bowel Syndrome (IBS) Prognosis

Alzheimer's Disease and the Microbiome

Gastritis Causes

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Risk Factors for Small Intestinal Bacterial Overgrowth

Parkinson's Disease and the Gut Microbiome

Conjunctiva microbiota

High FODMAP Foods and Low FODMAP Food Alternatives

Gastrointestinal Stromal Tumor (GIST) Treatment

Gastroparesis and Diet

Self-Help for Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Gastroschisis Prognosis

Mesentery: a new organ?

Short-Chain Fatty Acids (SCFAs)

Irritable Bowel Syndrome (IBS) and Diet

What is Gastroparesis?

Diabetic Gastroparesis

The Microbiome and Aging

What is a Gastric Bypass?

Celiac Disease Pathogenesis

Is Dermatitis Herpetiformis Caused by Herpes?

Inflammatory Bowel Disease (IBD) in Pregnancy

Gastritis Diagnosis

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Types of Gastrectomy

Do Serotonin and Antidepressants Affect the Microbiome?

Symptoms of Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) Epidemiology

What is Gastroenteritis?

FODMAPs and Irritable Bowel Syndrome (IBS)

Gastroparesis Causes

Antibiotics and the Microbiome

Fecal Microbiota Transplant Regulation

FODMAP Research

Gastric Varices - Signs and Symptoms

Fecal Microbiota Transplant

Skin Microbiota

Treatment and Prognosis for Intestinal Malrotation

Gastritis Symptoms

Gastric Carcinoma

Gastroparesis Epidemiology

Treatment of Irritable Bowel Syndrome

What is Vaginal Microbiome?

What does Sleeve Gastrectomy Involve?

Irritable Bowel Syndrome (IBS) Differential Diagnosis

Celiac Disease Symptoms

Gastrointestinal Disease and Skin Problems

Human Microbiome

Causes of Gastro-Esophageal Reflux Disease (GERD)

Gastritis Treatments

Irritable Bowel Syndrome (IBS) and Infections

What is Gastritis?

Fecal Microbiota Transplant Technique

Probiotics and IBS

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Gastroparesis Diagnosis

Gastric Bypass Benefits

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Microbiome-Host Cell Interactions

What is Celiac Disease?

Irritable Bowel Syndrome (IBS) and Stress Response

Effects of a Gluten-Free Diet on the Gut Microbiota

Genetics of Inflammatory Bowel Disease (IBD)

Irritable Bowel Syndrome (IBS) and Fibromyalgia

Achievements of the Human Microbiome Project

Crohn's Disease Cause

Gastrointestinal Bleeding Treatment

Fermented Foods and Gut Health

Microbiome and Cancer

Gastroparesis Treatments

Gastric Bypass Complications

Oral Microbiota

Dysbiosis and the Microbiome

What is Gastrointestinal Bleeding?

Celiac Disease Diagnosis

How Does the Diet Impact Microbiota?

What is Gastroenterology?

Disease Susceptibility and the Microbiome

Drug Metabolism and Microbiome

Human Microbiome Project (HMP)

Dysbiosis and Aging

Inflammatory Bowel Disease and Colorectal Cancer

Irritable Bowel Syndrome (IBS) Food Triggers

Causes of Irritable Bowel Syndrome

Dermatitis Herpetiformis and Celiac Disease

Microbiome and Disease

Gastric Bypass Types

Ulcerative Colitis Causes

Post-Infectious Irritable Bowel Syndrome

Gastric Varices

Latest Gastrointestinal Health News and Research

New research reveals why fiber-rich diets fuel you better than refined foods

This study quantifies how much energy the human body harvests from gut microbial fermentation of dietary fiber, integrating bacterial physiology, diet, and metagenomic data. Results reveal that dietary fiber, not microbiome composition, mainly determines the amount of short-chain fatty acids absorbed, impacting daily energy and metabolic health.

31 Jul 2025

Artificial sweetener may undermine effectiveness of cancer treatment

Sucralose is a popular sugar substitute for people who are cutting calories or managing blood sugar levels, but new research by the University of Pittsburgh and UPMC Hillman Cancer Center suggests that the artificial sweetener may not be the best choice for patients undergoing cancer immunotherapy.

31 Jul 2025

Gut bacteria produce hormone-like proteins that regulate weight and blood sugar

Our intestines are home to trillions of microorganisms that produce substances capable of regulating all the body's organs via the bloodstream and the gut's nervous system.

31 Jul 2025

Using tongue coating to spot early signs of Parkinson’s disease

Tongue coating analysis reveals potential biomarkers for early Parkinson's disease detection, offering a non-invasive and cost-effective diagnostic approach.

31 Jul 2025

Immunocompromised people are susceptible to skin cancer caused directly by beta-HPV

Researchers at the National Institutes of Health (NIH) have shown for the first time that a type of human papillomavirus (HPV) commonly found on the skin can directly cause a form of skin cancer called cutaneous squamous cell carcinoma (cSCC) when certain immune cells malfunction.

30 Jul 2025

Low FODMAP diet found to repair leaky gut in IBS-D patients

In a study, patients with irritable bowel syndrome with diarrhea, or IBS-D, who went on a low FODMAP diet saw an improvement of colonic barrier dysfunction, commonly known as "leaky gut."

30 Jul 2025

Harnessing the power of gut bacteria to enhance cancer immunotherapy effectiveness

A comprehensive new review reveals both the promise and challenges of using fecal microbiota transplantation (FMT) to enhance cancer immunotherapy effectiveness.

30 Jul 2025

Study identifies risk factors for second colorectal cancer in people with Lynch syndrome

A current study by the German Familial Colorectal Cancer Consortium is looking at the question of which people with Lynch syndrome are at an increased risk of developing a second colorectal cancer.

30 Jul 2025

Canadian scientists trap gut microbe fuel to improve blood sugar and liver health

A team of Canadian scientists has discovered a surprising new way to improve blood sugar levels and reduce liver damage: by trapping a little-known fuel made by gut bacteria before they wreak havoc on the body.

30 Jul 2025

Immune cells migrate from the gut to breast during pregnancy and lactation

Of the 3.6 million babies born in the United States each year, around 80 percent begin breastfeeding in their first month of life.

30 Jul 2025

Study confirms post-pandemic rise in disorders of gut-brain interaction

A new international study confirmed a significant post-pandemic rise in disorders of gut-brain interaction, including irritable bowel syndrome (IBS) and functional dyspepsia, according to the paper published in Clinical Gastroenterology and Hepatology.

30 Jul 2025

Blood-based tests show promise for colorectal cancer screening but follow-up challenges persist

A study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while blood-based tests offer a more convenient option for colorectal cancer screening, only 49% of patients completed a follow-up colonoscopy within six months, and just 56% did so at any point during the two-year study period.

29 Jul 2025

The Mount Sinai Hospital named among nation’s top 20 for care excellence

The Mount Sinai Hospital, the flagship hospital of Mount Sinai Health System, was listed among the nation's top 20 hospitals for care excellence by U.S. News & World Report for 2025-26, marking the 10th consecutive year the hospital has been listed on the publication's "Honor Roll."

29 Jul 2025

Gut hormone INSL5 linked to chronic diarrhea in patients with bile acid malabsorption

High levels of a hormone found in cells in the gut could underlie many cases of chronic diarrhea and help explain up to 40% of cases of patients with irritable bowel syndrome with diarrhea, according to a new study led by scientists at the University of Cambridge.

29 Jul 2025

Rising liver cancer rates highlight need for urgent action worldwide

The majority of liver cancer cases could be prevented by reducing levels of viral hepatitis, alcohol consumption and MASLD (metabolic dysfunction-associated steatotic liver disease – previously called non-alcoholic fatty liver disease), suggests an analysis as part of The Lancet Commission on liver cancer.

29 Jul 2025

Gut mycobiota could help predict disability in multiple sclerosis

Gut fungal communities may impact multiple sclerosis severity, offering new insights into MS pathogenesis and potential microbiome-based treatment strategies.

29 Jul 2025

What’s better for your gut: lean beef or chicken? Science weighs in

A crossover trial in healthy young adults found that both lean chicken and beef diets reduced gut microbial richness, but only chicken caused significant diversity loss. The study highlights that lean local beef may have a milder impact on the gut microbiome than chicken.

29 Jul 2025

How a leaky gut could be putting your heart at risk

Researchers reviewed recent studies showing that gut dysbiosis contributes to heart failure by weakening the gut barrier, enabling harmful metabolites like TMAO to trigger inflammation and cardiac damage. The review highlights a bidirectional “gut-heart axis” and points to new avenues for dietary and microbial therapies.

28 Jul 2025

New computer program mimics cell behavior for faster medical discoveries

Using mathematical analysis of patterns of human and animal cell behavior, scientists say they have developed a computer program that mimics the behavior of such cells in any part of the body.

28 Jul 2025

Simple UV technology reduces the number of respiratory infections in aged care facilities

Simple technology that harnesses ultraviolet light to 'zap' airborne viruses has been shown to significantly lower the number of respiratory infections in aged care facilities, paving the way for smarter infection control.

28 Jul 2025