Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

Is There a Link Between Migraine and the Gut Microbiome?

Gastrointestinal Stromal Tumor (GIST) Treatment

Mesentery: a new organ?

After Gastric Bypass Surgery

What is Gastroschisis?

Dermatitis Herpetiformis and Celiac Disease

Treatment of Gastric Varices

Microbiome-Host Cell Interactions

Celiac Disease Screening

Genetics of Inflammatory Bowel Disease (IBD)

Treatment and Prognosis for Intestinal Malrotation

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Gastric Varices

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Sarin Classification of Gastric Varices

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

Effects of a Gluten-Free Diet on the Gut Microbiota

What is Irritable Bowel Syndrome?

Gastric Bypass Types

What does Sleeve Gastrectomy Involve?

Gastritis Diagnosis

Types of Gastrectomy

Disease Susceptibility and the Microbiome

Diabetic Gastroparesis

Gastric Bypass Criteria

Symptoms of Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) Prognosis

Dysbiosis and Aging

Gastric Bypass Benefits

What is Gluten?

Gastrointestinal Stromal Tumor Pathogenesis

Gastroparesis and Diet

Causes of Irritable Bowel Syndrome

Alzheimer's Disease and the Microbiome

Irritable Bowel Syndrome (IBS) and Fibromyalgia

Skin Microbiota

High FODMAP Foods and Low FODMAP Food Alternatives

Fecal Microbiota Transplant Technique

How to Recover Gut Health After Clostridium difficile Infection

Low FODMAP Diet

Does the Microbiome Interact with the Human Endocrine System?

What is Vaginal Microbiome?

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Malrotation of the Gastrointestinal Tract

The Microbiome and Aging

Probiotics and IBS

FODMAP Research

Celiac Disease Diagnosis

Genetic Factors that Influence Bacterial Diversity in the Human Gut

Irritable Bowel Syndrome (IBS) and Exercise

Gastrointestinal Bleeding Symptoms

What is Gastroenterology?

Gastroparesis Diagnosis

Gastrointestinal Bleeding Treatment

Crohn's Disease Cause

What is Gastrointestinal Bleeding?

Inflammatory Bowel Disease (IBD) in Pregnancy

What is Ulcerative Colitis?

Gastroparesis Causes

Fecal Microbiota Transplant Regulation

Irritable Bowel Syndrome (IBS) Research

What is Gastroenteritis?

Gastroschisis Prognosis

Gastroparesis Symptoms

Ulcerative Colitis Causes

Celiac Disease Pathogenesis

Celiac Disease Treatment

Inflammatory Bowel Disease and Colorectal Cancer

Irritable Bowel Syndrome (IBS) and Infections

Gut-on-a-Chip to Model Coeliac Disease

Gastric Carcinoma

Antibiotics and the Microbiome

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Gastritis Symptoms

What is Gastroparesis?

Symptoms and Diagnosis of Intestinal Malrotation

Fermented Foods and Gut Health

Oral Microbiota

Is Dermatitis Herpetiformis Caused by Herpes?

Irritable Bowel Syndrome (IBS) Psychological Therapies

Gastroschisis Causes

Gastrointestinal Stromal Tumor (GIST) Causes

Gastroparesis Treatments

How Does the Diet Impact Microbiota?

What is a Gastric Bypass?

Gastritis Treatments

Does Wheat Cause Gut Inflammation?

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Self-Help for Irritable Bowel Syndrome (IBS)

Fecal Microbiota Transplant

Risk Factors for Small Intestinal Bacterial Overgrowth

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Treatment of Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) Food Triggers

Gastroparesis Epidemiology

Gut Microbiota

Human Microbiome Project (HMP)

Do Serotonin and Antidepressants Affect the Microbiome?

Irritable Bowel Syndrome (IBS) Epidemiology

Irritable Bowel Syndrome (IBS) and Diet

Post-Infectious Irritable Bowel Syndrome

Gastric Bypass Complications

Irritable Bowel Syndrome (IBS) and Stress Response

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Diagnosis of Irritable Bowel Syndrome

What is Celiac Disease?

Conjunctiva microbiota

Achievements of the Human Microbiome Project

Celiac Disease Symptoms

Dysbiosis and the Microbiome

Microbiome and Cancer

What is Gastritis?

Irritable Bowel Syndrome (IBS) Differential Diagnosis

Gastritis Causes

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

Drug Metabolism and Microbiome

Gastrointestinal Disease and Skin Problems

Causes of Gastro-Esophageal Reflux Disease (GERD)

Human Microbiome

Short-Chain Fatty Acids (SCFAs)

Microbiome and Disease

FODMAPs and Irritable Bowel Syndrome (IBS)

Mechanism of Irritable Bowel Syndrome (IBS)

Gastric Varices - Signs and Symptoms

Parkinson's Disease and the Gut Microbiome

Irritable Bowel Syndrome (IBS) Comorbidities

Latest Gastrointestinal Health News and Research

New triple action iron supplement restores iron levels without inflammation

Iron-deficiency anemia is a common condition marked by tiredness, headaches or ice cravings. But the oral iron supplements used to treat it can leave behind excess iron that causes inflammation and an upset stomach.

15 Oct 2025

Targeting bacterial communication may offer antibiotic-free wound therapy

Researchers at University of California San Diego School of Medicine have discovered a previously unrecognized mechanism by which Staphylococcus aureus - one of the most common causes of skin and soft tissue infections worldwide - delays wound healing.

15 Oct 2025

Pioneering personalized medicine by deciphering depression's complex biological web

In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Najaf Amin unveils transformative insights that fundamentally reshape international understanding of depression genetics.

15 Oct 2025

How shifting antibodies fuel aging and the new therapies aiming to slow it

This review uncovers how aging reshapes immunoglobulins, particularly IgG, IgM, and IgA, driving inflammation, cellular senescence, and tissue degeneration. By dissecting B-cell dysfunction, glycosylation changes, and Fc receptor pathways, it reveals immunoglobulins as both biomarkers and potential therapeutic targets in aging.

14 Oct 2025

Western diet fuels IBD by derailing the microbiome - can precision nutrition turn the tide?

This review examines how Western dietary patterns, high in ultra-processed foods, salt, and unhealthy fats, disrupt gut microbiota, impair immune regulation, and contribute to the global rise of inflammatory bowel disease (IBD). It highlights systems biology and nutritional epidemiology as essential tools to develop personalised dietary strategies and shift IBD care from treatment to prevention.

12 Oct 2025

Microbial genetic variation shapes neurocognitive behavior in sheep

The researchers used Merino sheep as an animal model, systematically collecting samples of their hindgut and ruminal microbiota, plasma metabolites, and neurocognitive behavioral phenotype data.

10 Oct 2025

Drinking soft drinks may fuel depression by altering gut bacteria

A study links soft drink consumption to increased depression risk, highlighting gut microbiome changes, particularly in women. Learn more about the findings.

10 Oct 2025

UCLA scientists uncover the role of DGRs in structuring the infant gut microbiome

Everywhere you go, you carry a population of microbes in your gastrointestinal tract that outnumber the human cells making up your body.

10 Oct 2025

Study reports the world's first genetically engineered pig-to-human liver xenotransplantation

An important new study in the Journal of Hepatology, published by Elsevier, reports the world's first auxiliary liver xenotransplant from a genetically engineered pig to a living human recipient.

9 Oct 2025

Changes in the gastric microbiota linked to growth of neuroendocrine tumors

Researchers from Osaka Metropolitan University have discovered how the balance of bacteria in the stomach affects the growth of neuroendocrine tumors (NETs).

8 Oct 2025

Study links extended breastfeeding to stronger infant immune health

Breastfeeding until at least six months helps babies to fight off infections and reduces chronic inflammation, according to a new study. And better understanding the way specific nutrients in breast milk impact the immune system will improve health outcomes for all infants including those not breastfed.

8 Oct 2025

Non-standard baby formula linked to faster infant growth

The use of non-standard infant formulas is associated with higher growth rates in the first year, necessitating further research on long-term health effects.

8 Oct 2025

Second World Congress to spotlight the science behind mitochondrial biology and microbiome research

The Second World Congress on Targeting Extracellular Vesicles (EVs) is scheduled for 15–16 October 2025 in Valencia, Spain. This landmark event, co-organized by the World Mitochondria Society and the International Society of Microbiota, will spotlight the rapidly evolving science where mitochondrial biology and microbiome research intersect via extracellular vesicles.

7 Oct 2025

Innovative approaches target PAR2 receptor to alleviate gut pain

Abdominal pain is a hallmark of many digestive disorders, including inflammatory bowel disease and irritable bowel syndrome.

7 Oct 2025

'Good' gut microbe found to support fetal growth and reduce pregnancy risks

Research led by the University of Cambridge has found the first clear evidence that the 'good' gut bacteria Bifidobacterium breve in pregnant mothers regulates the placenta's production of hormones critical for a healthy pregnancy.

6 Oct 2025

Microplastics can alter the human gut microbiome, research shows

New research presented today at UEG Week 2025 shows that microplastics – plastic particles smaller than 5mm commonly found in the environment – can alter the human gut microbiome, with some changes resembling patterns linked to depression and colorectal cancer.

6 Oct 2025

Artificially-sweetened and sugary drinks linked to higher risk of non-alcoholic fatty liver disease

A major new study reveals that both sugar-sweetened beverages (SSBs) and low- or non-sugar-sweetened beverages (LNSSBs) are significantly associated with a higher risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD).

6 Oct 2025

Advancing precision medicine to transform obesity prevention and treatment

A new report led by researchers at Pennington Biomedical Research Center underscores the growing potential of precision medicine to transform how obesity is prevented, diagnosed and treated, while also illuminating key gaps and challenges that must be addressed.

6 Oct 2025

AI serves as a tool to fight drug resistance and accelerate new antibiotic development

Researchers at McMaster University and the Massachusetts Institute of Technology (MIT) have made two scientific breakthroughs at once: they not only discovered a brand-new antibiotic that targets inflammatory bowel diseases (IBD), but also successfully used a new type of AI to predict exactly how the drug works. To their knowledge, this a global first for the AI.

3 Oct 2025