Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Merck, Pfizer and Corning join forces to modernize pharmaceutical glass packaging

Merck, Pfizer and Corning Incorporated today announced collaborations that have enabled the modernization of pharmaceutical packaging with the introduction of Corning Valor Glass.

20 Jul 2017

University of Sussex receives £428K grant for skin cancer research

The University of Sussex is to carry out vital research into skin cancer thanks to a new grant from The Engineering and Physical Sciences Research Council.

20 Jul 2017

UW-Madison researchers jump major hurdle on path toward wider use of stem cells

Since highly versatile human stem cells were discovered at the University of Wisconsin-Madison nearly 20 years ago, their path to the market and clinic has been slowed by a range of complications.

14 Jul 2017

Mayo Clinic and nference launch startup to develop drugs for rare diseases

Today, Mayo Clinic and nference launch a startup company for drug development that will be powered by clinical expertise and artificial intelligence (AI).

14 Jul 2017

Computational analysis of open-access data points to new ways of using drugs

A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been approved for other uses.

12 Jul 2017

UNC-Chapel Hill researchers find undesirable issues with widely-used drug screening tool

A widely used screening tool deployed in the early phases of drug discovery to weed out undesirable compounds is wrong so often it can't be trusted on its own, according to scientists at the University of North Carolina at Chapel Hill.

11 Jul 2017

AI and deep learning can help visualize human bias in complex systems

Since 2015 artificially-intelligent systems surpassed human accuracy in many tasks including image recognition, voice recognition, autonomous driving and strategy games such as GO. Early experiments such as Beauty.

11 Jul 2017

Novel small molecule tracer for PET imaging spots blood clots

Blood clots in veins and arteries can lead to heart attack, stroke, and pulmonary embolism, which are major causes of mortality.

6 Jul 2017

ActuRx and Insillico Medicine collaborate to prevent, treat age-related illnesses

Can big data and financial engineering cure Cancer, Alzheimer's, and other age-related illnesses? ActuRx and Insillico Medicine think so.

5 Jul 2017

Researchers discover biological link between gut bacteria metabolism and obesity

Cleveland Clinic researchers have uncovered a biological link between gut bacteria metabolism and obesity.

30 Jun 2017

New antiviral drug candidate effective against broad range of coronaviruses

A new antiviral drug candidate inhibits a broad range of coronaviruses, including the SARS and MERS coronaviruses, a multi-institutional team of investigators reports this week in Science Translational Medicine.

29 Jun 2017

Mouse brain models reveal insights into genetics of autism

While the definitive causes remain unclear, several genetic and environmental factors increase the likelihood of autism spectrum disorder, or ASD, a group of conditions covering a "spectrum" of symptoms, skills and levels of disability.

28 Jun 2017

Novel Nanopsis technology quadruples magnification power of regular optical microscope

A British nanotech invention has revolutionized the humble optical microscope by quadrupling its magnification power to a level far beyond what could previously be achieved with visible light.

23 Jun 2017

Wasp venom provides clues to how genes take on new functions

Amid the incredible diversity of living things on our planet, there is a common theme. Organisms need to acquire new genes, or change the functions of existing genes, in order to adapt and survive.

22 Jun 2017

New algorithm shortens drug discovery times from years to months

An algorithm developed at the Hebrew University cuts through the immense number of possible solutions to shorten drug discovery times from years to months.

22 Jun 2017

Researchers identify key protein that helps trigger ketamine's rapid antidepressant effects

UT Southwestern Medical Center scientists have identified a key protein that helps trigger ketamine's rapid antidepressant effects in the brain, a crucial step to developing alternative treatments to the controversial drug being dispensed in a growing number of clinics across the country.

22 Jun 2017

Emphasis on nanotechnology, pharmaceutical science, forensics, food safety and bioanalytical for Pittcon's annual call for papers

The Program Committee is pleased to announce the call for papers for the Pittcon 2018 Technical Program. Abstracts are currently being accepted for contributed oral and poster presentations in all areas of analytic chemistry and applied spectroscopy in applications such as, but not limited to, environmental science, food science, energy research, and informatics.

From Pittcon 20 Jun 2017

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Domainex Ltd. expands its partnership with Imperial College London, to discover novel therapies that reduce heart muscle damage during heart attacks. The aim is to discover a drug that inhibits the enzyme MAP4K4, which plays a key role in triggering cell death following a heart attack.

19 Jun 2017

Researchers recapitulate pathological condition of retinal diseases on a chip

Approximately 80% of all sensory input is received via the eyes, so suffering from chronic retinal diseases that lead to blindness causes a significant decrease in the quality of life (QOL).

15 Jun 2017

Scientists discover new approach for antifungal drug treatments

Each year, invasive fungal infections sicken an estimated 2 million people worldwide and kill nearly 800,000 - but a team of international scientists have discovered a new approach for antifungal drug treatments.

15 Jun 2017

Drug Discovery News and Research

Further Reading

Merck, Pfizer and Corning join forces to modernize pharmaceutical glass packaging

University of Sussex receives £428K grant for skin cancer research

UW-Madison researchers jump major hurdle on path toward wider use of stem cells

Mayo Clinic and nference launch startup to develop drugs for rare diseases

Computational analysis of open-access data points to new ways of using drugs

UNC-Chapel Hill researchers find undesirable issues with widely-used drug screening tool

AI and deep learning can help visualize human bias in complex systems

Novel small molecule tracer for PET imaging spots blood clots

ActuRx and Insillico Medicine collaborate to prevent, treat age-related illnesses

Researchers discover biological link between gut bacteria metabolism and obesity

New antiviral drug candidate effective against broad range of coronaviruses

Mouse brain models reveal insights into genetics of autism

Novel Nanopsis technology quadruples magnification power of regular optical microscope

Wasp venom provides clues to how genes take on new functions

New algorithm shortens drug discovery times from years to months

Researchers identify key protein that helps trigger ketamine's rapid antidepressant effects

Emphasis on nanotechnology, pharmaceutical science, forensics, food safety and bioanalytical for Pittcon's annual call for papers

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Researchers recapitulate pathological condition of retinal diseases on a chip

Scientists discover new approach for antifungal drug treatments

eBook: Essential guide to organoids in drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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