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The Human Mini Heart-in-a-Jar That Could One Day Replace Animal Testing

An interview with Dr. Kevin Costa, discussing the miniaturized heart-in-a-jar model developed by Novoheart, and its applications in personalized medicine.

12 Nov 2018

Monash researchers provide insight into intricate peptide changes affecting immune system

Human leukocyte antigen molecules are a group of proteins that help the immune system identify foreign invaders such as viruses and bacteria and which impact a wide variety of clinical outcomes including infection and cancer.

8 Nov 2018

Targeted radiation provides treatment option for children with hard-to-treat liver cancer

Targeted tumor radiation provides a feasible treatment option for children with difficult-to-treat liver cancer, according to a new study published today in the journal Pediatric Blood and Cancer.

8 Nov 2018

Regenerative medicine scientist receives $1.3 million to study stem cell therapy for liver failure

Currently, the only therapy for metabolic liver disease is an organ transplant. Tracy Grikscheit, MD, an attending physician and regenerative medicine scientist at Children's Hospital Los Angeles, hopes to change that reality.

7 Nov 2018

Study elucidates genetic causes of severe cardiomyopathies in children

Cardiac muscle degeneration (cardiomyopathy) is the most common cause of severe cardiac dysfunction and life-threatening cardiac arrhythmias in children. These severe disorders often lead to consideration of heart transplant. However, their actual cause - the genetic basis - has been poorly characterized.

7 Nov 2018

New nano-immunotherapy promotes long-term acceptance of transplanted organs

Researchers at the Mount Sinai School of Medicine have developed a new nanotechnology-based immunotherapy that promotes long-term transplant acceptance in an animal model.

7 Nov 2018

Scientists create tiny, biodegradable scaffold to transplant stem cells and deliver drugs

Rutgers scientists have created a tiny, biodegradable scaffold to transplant stem cells and deliver drugs, which may help treat Alzheimer's and Parkinson's diseases, aging brain degeneration, spinal cord injuries and traumatic brain injuries.

5 Nov 2018

Researchers take first step in bioengineering human uterus to treat endometrial diseases

Researchers at Northwestern Medicine have taken the first step in bioengineering the human uterus to treat endometriosis, uterine-factor infertility and endometrial cancer.

1 Nov 2018

Celprogen successfully prints 3D Brains from brain stem cells to study neurological disease stages

Celprogen Inc., a leader in the Stem Cell Research and Therapeutics industry for stem cell research since 2002, today announced that they have successfully finished printing 3D Brains from brain stem cells for studying neurological disease stages.

1 Nov 2018

Researchers discover biomarker for most common type of heart failure

A team led by a Cedars-Sinai physician-scientist has discovered a biomarker--a protein found in the blood--for the most common type of heart failure, a new study published today in JAMA Cardiology shows.

1 Nov 2018

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. An international team’s work has shed new light on a molecule called TIM-3 that might play a key role in the regulation of the immune response.

31 Oct 2018

Physician-scientists treat first patient in the U.S. with focused ultrasound for neuropathic leg pain

University of Maryland physician-scientists have treated the first patient in the United States with MRI-guided focused ultrasound for neuropathic leg pain as part of a pilot clinical trial.

30 Oct 2018

Study reveals one in ten people may opt-out of proposed system for organ donation

A new study has revealed that around one in 10 people are considering opting out of a proposed new system that aims to increase organ donation by presuming consent.

29 Oct 2018

Identifying ways to improve existing guidelines for ethical human-animal chimera research

In Greek mythology, a chimera is a figure with the head of a lion, the body of a goat, and the tail of a serpent. But the concept is not entirely imaginary.

25 Oct 2018

Study finds cluster of factors that may help predict C. diff infections

A cluster of factors may help predict which patients are likely to develop Clostridioides difficile, a potentially life-threatening disease commonly known as C. difficile or C. diff, a new study has found.

25 Oct 2018

Study explores whether wearable patches could help patients to monitor blood pressure

Because only half of the people in the United States diagnosed with high blood pressure have their condition under control, an easy, cost-effective method to monitor blood pressure would be a significant advance to reduce the risk of heart disease and stroke.

25 Oct 2018

MIT researchers devise way to help blood cells regenerate after radiation therapy

Patients with blood cancers such as leukemia and lymphoma are often treated by irradiating their bone marrow to destroy the diseased cells. After the treatment, patients are vulnerable to infection and fatigue until new blood cells grow back.

24 Oct 2018

Researchers find improvement in liver transplant survival rate among older recipients

An increasing number of older adults are diagnosed with end-stage liver disease. End-stage liver disease is a life-threatening condition in which the liver stops working normally.

23 Oct 2018

Map of human liver cells reveals molecular make-up of individual cells

A map of the cells in the human liver has been created by University Health Network Transplant Program and University of Toronto researchers, revealing for the first time differences between individual cells at the molecular level which can have a profound impact on their behaviour in tissue, tumours and disease.

From 10x Genomics, Inc. 23 Oct 2018

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Genentech, a member of the Roche Group, today announced positive results from the Phase III IMpower130 study of Tecentriq (atezolizumab) plus chemotherapy (carboplatin and Abraxane® [albumin-bound paclitaxel; nab-paclitaxel]) for the initial (first-line) treatment of people with previously untreated metastatic non-squamous non-small cell lung cancer.

22 Oct 2018

Transplant News and Research

The Human Mini Heart-in-a-Jar That Could One Day Replace Animal Testing

Monash researchers provide insight into intricate peptide changes affecting immune system

Targeted radiation provides treatment option for children with hard-to-treat liver cancer

Regenerative medicine scientist receives $1.3 million to study stem cell therapy for liver failure

Study elucidates genetic causes of severe cardiomyopathies in children

New nano-immunotherapy promotes long-term acceptance of transplanted organs

Scientists create tiny, biodegradable scaffold to transplant stem cells and deliver drugs

Researchers take first step in bioengineering human uterus to treat endometrial diseases

Celprogen successfully prints 3D Brains from brain stem cells to study neurological disease stages

Researchers discover biomarker for most common type of heart failure

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

Physician-scientists treat first patient in the U.S. with focused ultrasound for neuropathic leg pain

Study reveals one in ten people may opt-out of proposed system for organ donation

Identifying ways to improve existing guidelines for ethical human-animal chimera research

Study finds cluster of factors that may help predict C. diff infections

Study explores whether wearable patches could help patients to monitor blood pressure

MIT researchers devise way to help blood cells regenerate after radiation therapy

Researchers find improvement in liver transplant survival rate among older recipients

Map of human liver cells reveals molecular make-up of individual cells

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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