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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Differences in gut microbiome diversity attributed to dietary patterns in children with obesity

Differences in the dietary patterns of overweight or obese children contribute to variations in the gut microbiome diversity.

16 Feb 2023

A new trial to assess if butyrate can prevent colon cancer

Researchers discuss a new clinical trial that will determine the efficacy of butyrate administration in preventing colon cancer.

16 Feb 2023

Innovative software tool assembles truly complete genome sequences from many species

National Institutes of Health researchers have developed and released an innovative software tool to assemble truly complete (i.e., gapless) genome sequences from a variety of species.

16 Feb 2023

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

16 Feb 2023

Similar genes may lead to different patterns of fat distribution in women

Obesity causes many health problems and worsens several chronic illnesses, including type 2 diabetes and cardiovascular disease, however, some obese people are more susceptible to complications than others.

16 Feb 2023

Ultima Genomics partners with New England Biolabs® to expand research applications on Ultima Sequencers

Ultima Genomics, Inc., a developer of a revolutionary new ultra-high throughput sequencing architecture, today announced a collaboration to develop and enable use of New England Biolabs’ (NEB®) NEBNext® reagents and library preparation kits on Ultima sequencing platforms.

From Ultima Genomics, Inc. 16 Feb 2023

Brain cells may age faster in people with cocaine use disorder

A new study finds evidence from the DNA methylome that the biological age – different from the chronological age – of cells in Brodmann Area 9 of the prefrontal cortex might be greater in people with cocaine use disorder.

16 Feb 2023

Machine learning algorithm predicts DNA insertion efficiency of prime editing

A new tool to predict the chances of successfully inserting a gene-edited sequence of DNA into the genome of a cell, using a technique known as prime editing, has been developed by researchers at the Wellcome Sanger Institute.

15 Feb 2023

Reduced butyrate production in the microbiome of type 2 diabetics

Researchers observe reduced levels of butyrate-producing bacteria in the microbiome of type 2 diabetics.

15 Feb 2023

Comparative study on retinoic acid-inducible gene-I of humans and bats

In a recent study posted to the bioRxiv* preprint server, researchers cloned and functionally characterized the virus ribonucleic acid (RNA) sensor, retinoic acid-inducible gene-I (RIG-I), from the microbat Myotis daubentonii (Yangochiroptera suborder) and the megabat Rousettus aegyptiacus (Yinpterochiroptera suborder), and compared them to the human ortholog.

15 Feb 2023

Researchers identify a novel mechanism of DNA repair that occurs in neurons

"Use it or lose it" goes the adage, applied liberally to everything from our muscles to our minds, especially as we age.

15 Feb 2023

Computational modeling helps uncover genomic mutations that likely influenced human cognition

Researchers from the National Institutes of Health (NIH) used computational modeling to uncover mutations in the human genome that likely influenced the evolution of human cognition.

15 Feb 2023

Isolation of Burkholderia thailandensis from the environment

A new study in Emerging Infectious Diseases aimed to detect and isolate B. thailandensis from water and soil samples collected from Puerto Rico between December 2018 and March 2020 as well as Texas between November 2019 to November 2020.

15 Feb 2023

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

In a recent study posted to the bioRxiv* preprint server, researchers identified a novel antiviral pathway different from the interferon (IFN) pathway that inhibited poxvirus(es) replication.

15 Feb 2023

Cocaine use disorder leads to changes in the 'methylome' of a brain region

Scientists tend to view substance addiction as primarily a disease of the brain. When we enjoy sex, food, music, or hobbies, regions of our brain within the reward pathway are flooded with pleasure-inducing dopamine.

14 Feb 2023

Research examines whether meat or dairy-based complementary foods affect gut microbiota and growth

A new study in the journal Frontiers in Nutrition aimed to analyze the impact of complementary foods on the development of infant gut microbiota and whether it is associated with infant growth.

14 Feb 2023

Integrating AI with infrared imaging to improve colon cancer diagnosis

Artificial intelligence and infrared imaging automatically classify tumors and are faster than previous methods.

14 Feb 2023

Complete Genomics Drops Genome Sequencing Price to Sub $100 at AGBT General Meetin

Complete Genomics Inc., a global life science tools leader and subsidiary of MGI Tech Co., Ltd. (“MGI”), today launched new revolutionary products and prices at Advances in Genome Biology and Technology (AGBT) General Meeting.

From MGI 14 Feb 2023

New analytical platform quantifies the structure of mRNA-based medicines

Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA) based medicines.

13 Feb 2023

Long-term caloric restriction has a small effect on the DNA methylation measure of the pace of aging

Researchers assessed the impact of caloric restriction on biological aging among the comprehensive assessment of the long-term effects of reducing the intake of energy (CALERIE) randomized controlled trial participants.

13 Feb 2023

DNA News and Research

Further Reading

Differences in gut microbiome diversity attributed to dietary patterns in children with obesity

A new trial to assess if butyrate can prevent colon cancer

Innovative software tool assembles truly complete genome sequences from many species

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Similar genes may lead to different patterns of fat distribution in women

Ultima Genomics partners with New England Biolabs® to expand research applications on Ultima Sequencers

Brain cells may age faster in people with cocaine use disorder

Machine learning algorithm predicts DNA insertion efficiency of prime editing

Reduced butyrate production in the microbiome of type 2 diabetics

Comparative study on retinoic acid-inducible gene-I of humans and bats

Researchers identify a novel mechanism of DNA repair that occurs in neurons

Computational modeling helps uncover genomic mutations that likely influenced human cognition

Isolation of Burkholderia thailandensis from the environment

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

Cocaine use disorder leads to changes in the 'methylome' of a brain region

Research examines whether meat or dairy-based complementary foods affect gut microbiota and growth

Integrating AI with infrared imaging to improve colon cancer diagnosis

Complete Genomics Drops Genome Sequencing Price to Sub $100 at AGBT General Meetin

New analytical platform quantifies the structure of mRNA-based medicines

Long-term caloric restriction has a small effect on the DNA methylation measure of the pace of aging

eBook: A guide to RNA sequencing eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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