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Reconstruction surgery rarely discussed with breast cancer patients

A new study finds that most general surgeons do not discuss reconstruction with patients before surgical breast cancer treatment.

28 Dec 2007

Patient with AIDS finds heart-assit device is an option when transplant is not

Josh Bristow was in the late stages of heart failure when he came to the Emergency Department at Cedars-Sinai Medical Center on Aug. 25, 2007.

28 Dec 2007

Overeating and obesity triggered by lack of brain-derived neurotrophic factor

According to the Centers for Disease Control and Prevention, close to one-third of the population in the United States is obese and another third is overweight.

28 Dec 2007

Discovery of potential oral treatment for diabetes

Research in the Department of Biology at the Faculty of Science and Science Education of the University of Haifa has discovered a substance that may become an oral treatment for diabetes and its complications.

28 Dec 2007

NIEHS awards $6.8 million DISCOVER grants

The National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, is awarding a total of $6.8 million for the first year of funding to three new research centers called DISCOVER - Disease Investigation Through Specialized Clinically-Oriented Ventures in Environmental Research.

28 Dec 2007

New drug targets may fight tuberculosis and other bacterial infections in novel way

Over the course of the 20th Century, doctors waged war against infectious bacterial illness with the best new weapon they had: antibiotics.

28 Dec 2007

Personalized medicine will alter treatment of genetic disorders

One of the nation's pre-eminent genetic researchers, Eric Hoffman, PhD, of Children's Research Institute at Children's National Medical Center, predicts that in relatively short order, medicine's next innovation--individualized molecular therapies--will have the unprecedented ability to treat muscular dystrophies, and other disorders.

28 Dec 2007

Neglected tropical diseases, lymphatic filariasis, trachoma, leishmaniasis, onchocerciasis and schistosomiasis

Though little known to most Americans, lymphatic filariasis, trachoma, leishmaniasis, onchocerciasis, schistosomiasis and other so-called neglected tropical diseases are responsible for severe health burdens, especially among the world's poorest people.

28 Dec 2007

Model developed that predicts molecular response of living cells to genetic or environmental change

Scientists at the Institute for Systems Biology (ISB), in collaboration with researchers from New York University (NYU), have developed a model which rapidly characterizes and accurately predicts the molecular-level, mechanistic response of a free-living cell to genetic and environmental changes.

28 Dec 2007

Light powered platinum more targeted and powerful than similar cancer treatments

Researchers from the Universities of Warwick, Edinburgh, Dundee and the Czech Republic's Institute of Biophysics have discovered a new light-activated platinum-based compound that is up to 80 times more powerful than other platinum-based anti-cancer drugs and which can use "light activation" to kill cancer cells in much more targeted way than similar treatments.

28 Dec 2007

Optimal therapy for U.S. hepatitis C patients

As reported recently in the journal Hepatology, WIN-R, a multicenter study of over 5,000 patients with hepatitis C virus (HCV) showed treatment with weight-based REBETOL ribavirin, USP) (RBV) in combination with pegylated interferon (PEG-IFN) alfa-2b achieved significantly higher rates of sustained virologic response (SVR) and lower relapse rates compared to combination therapy using a flat dose of RBV 800 mg/day. Superior response was found particularly in patients with the most difficult-to-treat form of the disease, genotype 1 HCV. Efficacy was consistent across all weight groups.

28 Dec 2007

High triglycerides, other cholesterol raise risk of stroke

People with high triglycerides and another type of cholesterol tested but not usually evaluated as part of a person's risk assessment have an increased risk of a certain type of stroke, according to research published in the December 26, 2007, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Dec 2007

Health coverage improves health and reduces major heart complications

As presidential candidates ramp up their primary campaigns, health care reform looms prominently among voters' main concerns.

28 Dec 2007

New information about how normal cells and cancer cells survive under stress

Scientists report that an evolutionarily conserved transcription factor may have both positive and negative effects on the growth of tumors, depending on whether or not the tumor cells have enough oxygen.

28 Dec 2007

New immune system discovery will help fight hay fever and other allergies

A mechanism which can lead to hay fever and other allergic reactions, by preventing the immune system from regulating itself properly, has been discovered by scientists.

28 Dec 2007

Fibrosis in the liver stopped and reversed by researchers

University of California, San Diego researchers have proven in animal studies that fibrosis in the liver can be not only stopped, but reversed.

28 Dec 2007

FDA approves Voluven for blood loss post surgery

The U.S. Food and Drug Administration has approved Voluven, an intravenous solution that prevents and treats a dangerous loss of blood volume, a condition that sometimes occurs during and after surgery.

28 Dec 2007

Copy number variation may stem from replication misstep

Genome rearrangements, resulting in variations in the numbers of copies of genes, occur when the cellular process that copies DNA during cell division stalls and then switches to a different genetic "template," said researchers at Baylor College of Medicine in Houston in a report that appears today in the journal Cell.

28 Dec 2007

Variant of COMT gene linked to impulsive decisions

People with clinical addictions know first-hand the ravages the disease can take on almost every aspect of their lives.

28 Dec 2007

Cell-death receptor links cancer susceptibility and inflammation

For over 10 years, Wafik S. El-Deiry, MD, PhD, Professor of Medicine, Genetics, and Pharmacology at the University of Pennsylvania School of Medicine, has been pursuing a cancer-targeting molecule called TRAIL and its molecular partners.

28 Dec 2007