Research News and Research

RSS

Positive results from trial of investigational anti-epilepsy drug Brivaracetam

UCB has announced data demonstrating that anti-epileptic drug (AED) brivaracetam, with the proposed trade name Rikelta, administered as an adjunctive treatment in adults with refractory epilepsy with partial onset seizures, significantly reduced seizure frequency and had a side-effect profile comparable to placebo.

4 Dec 2007

Treating patients with psychiatric disorders for hepatitis C

People with severe mental illnesses are far more likely to be infected with Hepatitis C virus compared to the general population, however, they often do not get treatment for their liver disease because current antiviral therapies have known psychiatric side effects.

4 Dec 2007

Re-engineered Gleevec reduces heart risks

Using a new bottom-up approach for rational drug design, researchers at Rice University and the University of Texas M. D. Anderson Cancer Center have reengineered the powerful anticancer drug imatinib - best known by its brand name Gleevec - to more specifically target one type of cancer while potentially curbing a rare life-threatening cardiotoxic side effect.

4 Dec 2007

sLRP1-alpha provides relief from neuropathic pain

Injury to peripheral nerves (the causes of which include shingles, HIV-AIDS, toxins, alcoholism, repetitive motion disorders, surgery, and cancer) causes neuropathic pain, which differs from ordinary pain and is usually perceived as a steady burning, pins and needles, electric shock sensations, and/or tickling.

4 Dec 2007

Simple two-in-one test signals high risk after a heart attack

Everyone loves a two-fer, but a two-in-one heart test that has the potential to save lives is the real deal.

4 Dec 2007

New marker to identify cancer stem cells

Researchers at the University of Michigan Comprehensive Cancer Center have found a marker that can be used to identify stem cells in breast tumors, suggesting a potential simple test that could help determine the best treatment for breast cancer.

4 Dec 2007

Genetic markers for mental illness

Researchers have discovered natural genetic differences that might help predict the most effective antipsychotic drugs for particular patients with mental disorders such as schizophrenia, Parkinson's and drug addiction.

4 Dec 2007

Immediate relatives of patients with Parkinson's disease face increased risk of depression/anxiety disorders

Immediate relatives (brother, sister, mother, father, son or daughter) of people who have Parkinson's disease are at increased risk for developing depression and anxiety disorders, according to a new study by Mayo Clinic.

4 Dec 2007

Quality-improvement initiatives lead to progress in diabetes care

Two major initiatives designed to improve primary care treatment of type 2 diabetes have yielded significant benefits in largely minority, disadvantaged populations, according to a pair of studies in the December issue of Medical Care.

4 Dec 2007

Research may lead to more effective sunscreens

Chronic exposure to the sun increases the risk of an individual developing skin cancer because UV light from the sun can cause genetic mutations that enable cells in the skin to grow in an uncontrolled manner.

4 Dec 2007

New upper limit defined for normal ALT in adolescent males

A new cohort study of adolescent offenders in Australia has identified an upper limit for alanine aminotransferase (ALT) that is more sensitive for the diagnosis of liver disease.

4 Dec 2007

New smart pen and paper technology helps blind students

Subjects like physics, calculus and biology are challenging for most students, but imagine tackling these topics without being able to see the graphs and figures used to teach them.

4 Dec 2007

Mini transplant patients' outcomes similar using related and unrelated donor cells

People who undergo nonmyeloablative stem-cell transplants, or "mini transplants," for leukemia, lymphoma and other blood cancers have comparable outcomes regardless of whether they receive tissue-matched stem cells from a related or unrelated donor, according to new findings by researchers at Fred Hutchinson Cancer Research Center.

4 Dec 2007

Lymphatic vessel and lymph node function are restored with growth factor treatment

The frequent spread of certain cancers to lymph nodes often necessitates surgery or radiation therapy that damages the lymphatic system and can cause lymphedema, a condition of localized fluid retention that often increases susceptibility to infections.

4 Dec 2007

Few U.S. emergency rooms are properly equipped for children

In the first survey to specifically measure hospital pediatric preparedness, a team of Los Angeles Biomedical Research Institute (LA BioMed) researchers found few U.S. emergency rooms are properly equipped for children.

4 Dec 2007

Lead exposure hinders brain's ability to recover from injury

Exposure to lead can hinder the brain's ability to recover from injury, a recent study in laboratory animals shows.

4 Dec 2007

New recommendations provide evidence-based solutions to America's many health care problems

In a new evidence-based paper, the American College of Physicians (ACP) analyzes health care in the United States and 12 other industrialized countries and identifies lessons that could be applied to the particular political and social culture of the United States to achieve a high performing health care system, including achieving universal health insurance coverage for all Americans.

4 Dec 2007

Public-health approach for HIV control in India needs to become more scientific

The 2007 UNAIDS/WHO AIDS epidemic update released last week has revised the global estimate of HIV/AIDS primarily due to a major reduction of the estimate for India to 2.5 million people living with HIV/AIDS, which is less than half of the previous official estimate of 5.7 million people.

4 Dec 2007

Johns Hopkins Children's Center receives Gates funding for tuberculosis bacterium tracker

Johns Hopkins Children's Center has received a $946,000 grant from the Bill & Melinda Gates Foundation to design a system that visually tracks the behavior of the tuberculosis bacterium in the body and its response to current and new drug treatments.

4 Dec 2007

Heavy drinking, linked to high number of sex partners in young adults

Psychiatry researchers at Washington University School of Medicine in St. Louis have found that a clinical diagnosis of alcohol dependence in young adults is associated with having a high number of sex partners.

4 Dec 2007