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Potential new targeted treatments for Lupus

New research provides clues about the causes of lupus symptoms and suggests specific new targeted treatment strategies, according to Nilamadham Mishra, M.D., from Wake Forest University Baptist Medical Center, in presentations this week at the American College of Rheumatology in Boston.

13 Nov 2007

Acne drug Roaccutane may disrupt serotonin production

New research has found that a drug used to treat severe forms of acne reduces the availability of the chemical serotonin, low levels of which have been linked to aggression and clinical depression.

13 Nov 2007

Research highlights important indicators of early-stage ovarian cancer

New research explains why some ovarian cancer patients are dying, while others survive, despite similar surgical and post-operative treatment.

13 Nov 2007

Research looks at how environment inside a living cell affects protein structure

The syrupy soup of proteins, ribosomes and membranes inside a living cell is so tightly packed it may increase the structural content of proteins by as much as 25 percent, according to new research from Rice University and the University of Houston (UH).

13 Nov 2007

Exercise and education improves function and symptoms in women with fibromyalgia

An exercise program that incorporates walking, strength training and stretching may improve daily function and alleviate symptoms in women with fibromyalgia, according to a report in the November 12, 2007 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

13 Nov 2007

New insights into cataracts

Using the tools and techniques of soft condensed matter physics, a research team in Switzerland has demonstrated that a finely tuned balance of attractions between proteins keeps the lens of the eye transparent, and that even a small change in this balance can cause proteins to aggregate and de-mix.

13 Nov 2007

Overexpression of neuroglobin reduces severity of Alzheimer's disease in mice

Mice genetically engineered to both overproduce the protein neuroglobin and to develop Alzheimer's disease (AD) had a much milder form of the disease when compared to mice engineered to have AD alone, researchers at the Buck Institute for Age Research have reported.

13 Nov 2007

New target for MS treatment found using old drug

A drug currently used to treat high blood pressure and heart failure has been found to reduce the symptoms of multiple sclerosis in mice.

13 Nov 2007

Back pain often over-treated

The Sydney University researchers, led by Mark Hancock from the University of Sydney Back Pain Research Group, followed 240 patients suffering from acute low back pain from their first visit to their GP through to recovery.

13 Nov 2007

New genetic lineage of Ebola virus discovered in great apes

The Zaire species of Ebolavirus (ZEBOV) remains the most virulent of the various known species. It alone is responsible for 88% of human deaths from haemorrhagic fever recorded since Ebola's discovery in 1976.

13 Nov 2007

Nanoviricide drug candidate effectiveness confirmed against rabies and influenzas

NanoViricides, Inc. has said that in a confirmatory study, their nanoviricide drug candidates exhibited a consistent 20% to 30% survival in the test animals.

13 Nov 2007

Mycophenolate mofetil therapy effective for reducing lupus flares

Mayo Clinic researchers have shown that an immunosuppressive drug used in organ transplant cases is effective in reducing flare-ups in patients with systemic lupus erythematosus (SLE)

13 Nov 2007

Lung cancer treatment leads to Irish honour

A new scanning technique to improve radiotherapy treatment of lung cancer has been developed by a team led by Dr Gerry Hanna, and Dr Alan Hounsell, from Queen’s University.

13 Nov 2007

Life-threatening gene defect related to thoracic aortic disease discovered

A research team led by scientists at The University of Texas Medical School at Houston has identified a defective gene that affects vascular smooth-muscle cells in people who suffer from hereditary thoracic aortic disease, which can kill victims with little warning in the prime of their lives.

13 Nov 2007

Optical non-invasive tool to test for decompression sickness

It may not rank among the top 10 causes of death, but decompression sickness can be fatal. Instead of waiting for symptoms to appear, a University of Houston professor is developing a laser-based system that can diagnose the sickness in a matter of seconds.

13 Nov 2007

Trial looks at ability of insulin to limit heart-tissue damage during a heart attack

The ability of insulin to limit heart-tissue damage during a heart attack will be tested in a landmark clinical trial led by Paresh Dandona, M.D., Ph.D., University at Buffalo Distinguished Professor in the departments of Medicine and Pharmacology and Toxicology in the UB School of Medicine and Biomedical Sciences.

13 Nov 2007

Anti-inflammation molecule helps fight MS-like disease

An immune system messenger molecule that normally helps quiet inflammation could be an effective tool against multiple sclerosis (MS). Neurology researchers led by Abdolmohamad Rostami, M.D., Ph.D., professor and chair of the Department of Neurology at Jefferson Medical College of Thomas Jefferson University and the Jefferson Hospital for Neuroscience in Philadelphia, have found that the protein interkeukin-27 (IL-27) helped block the onset or reverse symptoms in animals with an MS-like disease.

13 Nov 2007

Improved surgery technique for endothelial disease of the cornea

In a research presentation today at the American Academy of Ophthalmology's Annual Meeting, Massimo Busin, MD, department head and professor of ophthalmology at the Villa Serena Hospital, Forli, Italy, described a technique that significantly improved results in patients being treated for endothelial disease of the cornea, the transparent covering of the front of the eye that provides much of its optical power.

13 Nov 2007

Human Genome Sciences announces positive phase 2 LymphoStat-B results

Human Genome Sciences, Inc. has announced the presentation of Phase 2 clinical results demonstrating that LymphoStat-B (belimumab) achieved a sustained improvement in disease activity across multiple clinical measures, decreased the frequency of disease flares over time, and was well tolerated through 2.5 years on treatment in combination with standard of care in patients with active systemic lupus erythematosus (SLE).

13 Nov 2007

Dealing with ethnic diversity in healthcare

Guidelines and training for doctors have tried to address the problems they face when dealing with patients who come from cultures and ethnic groups different to their own.

13 Nov 2007