Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

LSTM scientists describe new approach to screening potential TB treatments

Scientists from LSTM's Research Centre for Drugs and Diagnostics (RCDD) have described in a paper published today in Scientific Reports, a new way of screening potential treatments for Tuberculosis (TB) which may assist in the identification and prioritisation of new therapies which could potentially reduce the duration of current TB treatment.

29 Mar 2017

Northwestern scientists develop miniature personalized female reproductive system for testing drugs

Northwestern Medicine has developed a miniature female reproductive tract that fits in the palm of your hand and could eventually change the future of research and treatment of diseases in women’s reproductive organs.

29 Mar 2017

Study highlights importance of long-term research in bringing new cancer therapies to market

New drugs to treat cancer that are now emerging are the end products of research begun in the 1970s and '80s, a new study by Bentley University has found, demonstrating the importance of long-term research in bringing new therapies to market.

28 Mar 2017

Insilico Medicine to present research findings in AI for drug discovery at BioDataWorld West Congress

Insilico Medicine, a Baltimore-based Big Data analytics company applying deep learning techniques to drug discovery, biomarker development and human longevity research will present and chair a panel at the BioDataWorld West, San Francisco, April 26-27.

25 Mar 2017

Researchers unravel how drug interacts with ribosome to halt protein production

The discovery of a chemical compound that halts the production of a small set of proteins while leaving general protein production untouched suggests a new drug search strategy: Find compounds that target undesired proteins before they are even made.

23 Mar 2017

Method used to pick up laboratory mice has major impact on result of mouse studies

A new study shows that how mice are picked up by the experimenter can substantially change their behaviour in cognitive tests. The work, by Dr Kelly Gouveia and Professor Jane Hurst from the University of Liverpool, was published in Scientific Reports today and funded by the NC3Rs .

23 Mar 2017

Mount Sinai researchers review progress made in using ketamine and other therapies to treat depression

Major depressive disorder (MDD) impacts 15 million Americans and is the leading cause of disability, yet current treatments possess limited efficacy.

17 Mar 2017

2017 was another big year for Pittcon, as global attendance and economic impacts are revealed

Pittcon 2017 brought together members from the scientific community from around the world with leading speakers, instructors and exhibiting companies.

From Pittcon 16 Mar 2017

Deep learning in healthcare: a move towards algorithmic doctors

People are constantly trying to find more ‘human’ ways to interact with technology. Could the same be achieved for how we approach our health too?

15 Mar 2017

Virginia Tech researchers move one step closer to understanding heart disease at microscopic level

Researchers are one step closer to understanding heart disease at a microscopic level, a breakthrough that could influence future treatments for millions of people.

7 Mar 2017

Deep learning transforms the drug discovery process in collaboration between Insilico Medicine and Life Extension

In March 2016 Insilico Medicine initiated a research collaboration with Life Extension to apply advanced bioinformatic methods and deep learning algorithms to screen for naturally occurring compounds that may slow down or even reverse the cellular and molecular mechanisms of aging. Today Life Extension (LE) launched a new line of nutraceuticals called GEROPROTECTTM, and the first product in the series called Ageless CellTM combines some of the natural compounds that were shortlisted by Insilico Medicine’s algorithms and are generally recognized as safe (GRAS).

7 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

Sartorius to Acquire Real-Time Live-Cell Analysis Pioneer and Leader Essen BioScience

Sartorius, a leading partner to the biopharmaceutical industry and laboratories, today signed an agreement to acquire U.S. based Essen BioScience Inc.,

From Sartorius 6 Mar 2017

Innovative ways to target antibiotic resistance in short term

There has been much recent talk about how to target the rising tide of antibiotic resistance across the world, one of the biggest threats to global health today.

3 Mar 2017

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

A new contract research laboratory operated by France-based NovAliX will provide pharmaceutical companies with access to high-resolution cryo-transmission electron microscopy (cryo-TEM) by Thermo Fisher Scientific for facilitating small molecule and biologic drug discovery.

3 Mar 2017

Case Western Reserve and VA team up to tackle rising problem of antibiotic resistance

Since the discovery of penicillin in 1928, antibiotics have made the world a much safer and healthier place. But Shakespeare was onto something when he asked if it's possible to have too much of a good thing. In the case of antibiotics, the answer is increasingly "yes."

3 Mar 2017

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Chemotherapy treatment targets and kills cancer cells in the body. However, even after treatment, some cancer cells may remain in the patient's system undetected.

2 Mar 2017

Compound from soil bacteria could translate into new drug lead for TB

A new treatment for tuberculosis (TB) is set to be developed using compounds derived from bacteria that live in soil - according an international collaboration of researchers, including the University of Warwick.

1 Mar 2017

Prior Scientific reports use of PLW20 Well Plate Loader for automated solubility testing

Prior Scientific reports how a leading drug discovery and development organisation has been using its PLW20 Well Plate Loader to determine the aqueous solubility of various chemicals over a concentration gradient of buffers.

1 Mar 2017

Novel NMR spectroscopy platform holds potential to revolutionize drug development practices

Implementation of a new nuclear magnetic resonance spectroscopy platform will provide professors Nicolas Doucet and Steven LaPlante of Centre INRS-Institut Armand-Frappier with a powerful new tool for conducting an ambitious research program aimed at identifying new therapeutic molecules.

28 Feb 2017

Drug Discovery News and Research

Further Reading

LSTM scientists describe new approach to screening potential TB treatments

Northwestern scientists develop miniature personalized female reproductive system for testing drugs

Study highlights importance of long-term research in bringing new cancer therapies to market

Insilico Medicine to present research findings in AI for drug discovery at BioDataWorld West Congress

Researchers unravel how drug interacts with ribosome to halt protein production

Method used to pick up laboratory mice has major impact on result of mouse studies

Mount Sinai researchers review progress made in using ketamine and other therapies to treat depression

2017 was another big year for Pittcon, as global attendance and economic impacts are revealed

Deep learning in healthcare: a move towards algorithmic doctors

Virginia Tech researchers move one step closer to understanding heart disease at microscopic level

Deep learning transforms the drug discovery process in collaboration between Insilico Medicine and Life Extension

New drug-like compound shows potential to treat symptoms of lupus

Sartorius to Acquire Real-Time Live-Cell Analysis Pioneer and Leader Essen BioScience

Innovative ways to target antibiotic resistance in short term

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

Case Western Reserve and VA team up to tackle rising problem of antibiotic resistance

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Compound from soil bacteria could translate into new drug lead for TB

Prior Scientific reports use of PLW20 Well Plate Loader for automated solubility testing

Novel NMR spectroscopy platform holds potential to revolutionize drug development practices

ELRIG Drug Discovery: Poster Sessions eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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