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Gastric bypass reduces mortality risk in severely obese patients

Severely obese patients who undergo gastric bypass surgery significantly reduce their risk of death from coronary heart disease, diabetes, and cancer, according to research published in the Aug. 23, 2007, issue of The New England Journal of Medicine.

24 Aug 2007

First finding of a metabolite in 1 sex only

Researchers at the University of Illinois at Chicago have discovered a chemical compound in male blue crabs that is not present in females -- the first time in any species that an entire enzyme system has been found to be activated in only one sex.

24 Aug 2007

First large-scale study of proteins inside human cells called Jurkat T cells

The study, which appears in the August issue of Molecular & Cellular Proteomics, could lead to a better understanding of how proteins inside a specific type of cell work together and may pave the way for future detailed studies of how proteins work in other types of cells.

24 Aug 2007

People ages 57 to 85 think of sexuality as an important part of life

The first comprehensive national survey of sexual attitudes, behaviors and problems among older adults in the United States has found that most people ages 57 to 85 think of sexuality as an important part of life and that the frequency of sexual activity, for those who are active, declines only slightly from the 50s to the early 70s.

24 Aug 2007

New ways to control fever-induced seizures

When your body cranks up the heat, it's a sign that something's wrong and a fever is designed to help fight off the infection.

24 Aug 2007

Proteomic analysis of human amniotic fluid

Researchers report in the August issue of Molecular & Cellular Proteomics the most complete list so far of proteins present in the human amniotic fluid, the liquid that surrounds a fetus during pregnancy.

24 Aug 2007

Scientists investigate initial molecular mechanism that triggers neuronal firing

Carnegie Mellon University chemists have solved a decade-long molecular mystery that could eventually help scientists develop drug therapies to treat a variety of disorders, including epilepsy and Alzheimer's disease.

24 Aug 2007

Insight into autism's origin in the brain

In the first study of its kind, researchers have discovered that in autistic individuals, connections between brain cells may be deficient within single regions, and not just between regions, as was previously believed.

23 Aug 2007

Rapamycin study is first stage in development of new treatment

Rapamycin isn't your ordinary potential anti-cancer drug…It had a long and somewhat exotic history before undergoing preclinical (laboratory-based) studies at St. Jude as part of a national Pediatric Preclinical Testing Program (PPTP) investigation of its anticancer activity.

23 Aug 2007

Cancer stem cell scientists get $1.7 million to develop new leukemia drugs

"Modern cancer treatments fail to get to the root of the cancer - the stem cells - which is why many cancers recur despite aggressive treatment."

23 Aug 2007

Global public health security in the 21st century

More than at any previous time in history, global public health security depends on international cooperation and the willingness of all countries to act effectively in tackling new and emerging threats.

23 Aug 2007

Just how big is a portion? shoppers misled over salt contents in foods

A study of products on supermarket shelves in Britain has revealed that consumers are being misled as to the salt content in some of the foods they buy.

23 Aug 2007

Gastric bypass gives the obese a longer life span

The latest research has shown that gastric bypass surgery not only helps obese people lose weight and look and feel better, but it also helps them live significantly longer.

23 Aug 2007

Slap and tickle in the sixties, seventies and eighties - those oldies are still at it!

According to a new study, for many seniors sex remains an important issue in their lives.

22 Aug 2007

Good cholesterol may be a bad guy after all!

Scientists are warning that the good cholesterol (HDL) known for it's ability to protect against heart disease, can turn nasty.

22 Aug 2007

Fruit bats the culprit in spreading Marburg virus

Scientists have found that fruit bats that roost in caves could be the culprits in the spread of the deadly Marburg virus.

22 Aug 2007

Cell-based sensor for analysis of EGFR biomarker expression in oral cancer

Using a microfluidic device designed to capture and enrich cells from biological samples, a research team at The University of Texas at Austin has developed a test that can detect an important early marker for oral squamous cell carcinoma, which accounts for more than 90 percent of oral cancers. Oral cancer is the sixth most common cancer worldwide and is difficult to detect early enough to treat successfully.

22 Aug 2007

Antitumour drugs impede DNA uncoiling by topoisomerase I

The annoying bulges of an overwound telephone cord that shorten its reach and limit a caller's motion help explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators led by Mary-Ann Bjornsti, Ph.D., at St. Jude Children’s Research Hospital, and Nynke Dekker, Ph.D., at Delft Technology University.

22 Aug 2007

Targeted quantum dot conjugates for siRNA delivery

Take a quantum dot, add a coating of poly(ethylene glycol) (PEG), and attach a homing peptide and a piece of small interfering RNA (siRNA), and the result is a targeted nanoparticle that can stop the production of a specific protein by a targeted cell.

22 Aug 2007