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Novel method of drug delivery to inhibit the growth of prostate cancer cells

Prostate cancer is the second leading cause of cancer-related death for men in the U.S. Present treatments for metastatic prostate cancer (cancer cells that spread to other parts of the body) include hormonal therapy, chemotherapy and radiotherapy, which frequently have serious side effects.

23 Jun 2007

Study to investigate how dietary iron is used by cells

A four-year study on iron metabolism within cells, an essential process that impacts both iron deficiency and iron toxicity, conditions responsible for a multitude of human diseases, is underway at the University at Buffalo funded by a $1.16 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

23 Jun 2007

Meaningful leisure can mean many things

No matter what form your summer break takes, the benefits of leisure time can be powerful.

23 Jun 2007

Insight into how cancerous tumors thrive

Using mathematical theory, UC Irvine scientists have shed light on one of cancer's most troubling puzzles -- how cancer cells can alter their own genetic makeup to accelerate tumor growth.

23 Jun 2007

Invertebrate immune systems are anything but simple

A hundred years since Russian microbiologist Elie Metschnikow first discovered the invertebrate immune system, scientists are only just beginning to understand its complexity.

23 Jun 2007

Why NSAIDs damage the tissue that lines the gastrointestinal tract

New versions of drugs like buffered aspirin and Vioxx could produce fewer harmful side effects thanks to research being done at Kansas State University's College of Veterinary Medicine.

23 Jun 2007

Inherited genes linked to toxicity of leukemia therapy

St. Jude investigators have discovered inherited variations in certain genes that make children with acute lymphoblastic leukemia (ALL) susceptible to the toxic side effects caused by chemotherapy medications.

23 Jun 2007

Scientists identify gene responsible for one type of Charcot-Marie-Tooth disorder

Scientists have identified the gene responsible for one type of Charcot-Marie-Tooth disorder, a common inherited neurological disease, thanks to the chance appearance of a strain of impaired 'pale tremor' mice in a University of Michigan research laboratory.

23 Jun 2007

U.S. FDA approves Lyrica (pregabalin), the first drug to treat fibromyalgia

The U.S. Food and Drug Administration has approved Lyrica (pregabalin), the first drug to treat fibromyalgia, a disorder characterized by pain, fatigue and sleep problems.

23 Jun 2007

Tamiflu could halve the pandemic influenza death toll versus no intervention

Treatment with the oral antiviral Tamiflu (oseltamivir) and prophylaxis for people exposed to infected patients could be one of the most cost-effective strategies for reducing illness and death during an influenza pandemic.

23 Jun 2007

Arpida receives FDA approval to initiate Phase II trial with intravenous iclaprim

Arpida Ltd. has announced that it has received approval from the US Food and Drug Administration for a Phase II trial with intravenous iclaprim in the treatment of patients with hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP) or healthcare-associated pneumonia (HCAP) suspected or confirmed to be due to Gram-positive pathogens.

23 Jun 2007

Review of the routine monitoring of growth in children of primary school age to identify growth-related conditions

No sound evidence supports weight monitoring to identify and treat obese children, according to a review of worldwide research published this month in the United Kingdom.

23 Jun 2007

Anacor finds novel mechanism for lead anti-fungal drug, AN2690

Anacor Pharmaceuticals, a privately held pharmaceutical company, has announced that the journal Science will publish results of research that details how AN2690, the company's lead clinical candidate, kills fungal cells by interfering with synthesis of a specific protein required for fungal growth.

23 Jun 2007

New understanding of modern pandemic infection

Human resistance to a retrovirus that infected chimpanzees and other nonhuman primates 4 million years ago ironically may be at least partially responsible for the susceptibility of humans to HIV infection today.

23 Jun 2007

Irish Smokefree law reduces smoking in the home

Around one in five Irish smokers are lighting up less at home since the introduction of the smoking ban in 2004, new research has revealed.

23 Jun 2007

Minority segregated schools hinder reading skills

Children in families with low incomes, who attend schools where the minority population exceeds 75 percent of the student enrollment, under-perform in reading, even after accounting for the quality of the literacy instruction, literary experiences at home, gender, race and other variables, according to a new study.

23 Jun 2007