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New drug-delivery system using nanomaterials

Researchers at UCLA have successfully manipulated nanomaterials to create a new drug-delivery system that promises to solve the challenge of the poor water solubility of today's most promising anticancer drugs and thereby increase their effectiveness.

8 Jun 2007

miRNAs shown to be a critical force behind the anti-proliferation potential of p53

Cold Spring Harbor Laboratory (CSHL) researchers led by Lin He, Xingyue He, and Professor and Howard Hughes Medical Investigator (HHMI) Greg Hannon have identified a family of micro RNAs (miRNAs) that enable a critical tumor suppressor network, called the p53 pathway, to fight cancer growth.

8 Jun 2007

Researchers discover how strokes trigger biochemical events that increase amyloid-beta production in the brain

Researchers from the MassGeneral Institute for Neurodegenerative Disorders (MGH-MIND) have discovered how the death of brain cells caused by a stroke or head injury may cause generation of amyloid-beta protein ? the key component of senile plaques seen in the brains of patients with Alzheimer's disease.

8 Jun 2007

New regulator of fat metabolism identified

Over the past several years, animal studies have shown that high-fat, low-carbohydrate “ketogenic” diets cause demonstrable changes in metabolism and subsequent weight loss.

8 Jun 2007

Scientists look at slow-freezing techniques for human tissue

The goal is to make human eggs, ovarian tissue, blood vessels, even whole organs available when needed.

8 Jun 2007

Funding to upgrade stem cell research facilities at UC San Diego

The University of California, San Diego (UCSD) Human Stem Cell Core Facility, which supports multiple research projects using stem cells to advance the understanding and ultimately the treatment of disease and injury, will receive a $2.8 million Shared Research Laboratory Grant from the California Institute for Regenerative Medicine (CIRM).

8 Jun 2007

Examination of cancer-related fatigue

In a special publication sent to thousands of oncologists nationwide this month, University of Rochester Medical Center scientists offer an in-depth examination of cancer-related fatigue, with hope that a better understanding of the topic will prompt new research and treatment.

8 Jun 2007

Researchers turn normal tissue cells into embryonic stem cells

Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body.

8 Jun 2007

Researchers develop criteria to detect bone mass deficiencies in children with chronic diseases

Pediatricians now have a practical tool to help determine whether children with chronic diseases like Crohn's, juvenile arthritis and anorexia nervosa or those undergoing cancer treatment are at increased risk for bone mass deficiencies, fracture or osteoporosis as they get older, according to a new study whose lead author is a researcher at Cincinnati Children's Hospital Medical Center.

8 Jun 2007

Gene found that increases risk for Alzheimer's disease

A study comparing more genetic markers in the DNA of people with and without Alzheimer's disease than ever before has enabled researchers to identify a common gene that appears to increase a person's risk for developing Alzheimer's disease.

8 Jun 2007

Embryonic stem cells can be created without eggs

Embryonic stem cells are unique because they can develop into virtually any kind of tissue type, an attribute called pluripotency.

8 Jun 2007

Pesticides elevate risk of brain tumours

Agricultural workers exposed to high levels of pesticides and people who use them on houseplants appear to have a greater risk of developing brain tumours, suggests a study published online ahead of print in Occupational and Environmental Medicine.

8 Jun 2007

Low levels of testosterone may increase the long-term risk of death in men over 50 years old

"The new study is only the second report linking deficiency of this sex hormone with increased death from all causes, over time, and the first to do so in relatively healthy men who are living in the community," said Gail Laughlin, Ph.D., assistant professor and study author.

8 Jun 2007

NIAID to tackle drug resistant TB

The National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), has released its NIAID Research Agenda for Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) Tuberculosis (TB).

8 Jun 2007

Discovery of new survival mechanism in common bacteria

Researchers at the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health, have discovered a survival mechanism in a common type of bacteria that can cause illness.

8 Jun 2007

New bacterium discovered, Bartonella rochalimae

A close cousin of the bacterium that debilitated thousands of World War I soldiers has been isolated at UCSF from a patient who had been on an international vacation.

8 Jun 2007

Secrets of working memory revealed

A newly discovered interplay of cells in one of the brain's memory centers sheds light on how you recall your grocery list, where you laid your keys, and a host of important but fleeting daily tasks.

8 Jun 2007

Underuse of pancreatectomy in the United States

More than half of eligible patients with operable, early-stage pancreatic cancer don't undergo potentially life-extending surgery, suggests a study published online in the Annals of Surgery, published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

8 Jun 2007

Angiogenesis gene polymorphisms predict tumor recurrence in stage II and III colon cancer

Researchers at the University of Southern California (USC) have identified specific molecular markers that may help to predict tumor recurrence in stage II and III colon cancer patients.

8 Jun 2007

Metabolic syndrome may be associated with compromised heart structure and function

Typified by high blood pressure, weight gain around the waist and problems regulating blood sugar, metabolic syndrome may also be associated with compromised heart structure and function, according to a paper published in the online open access journal BMC Cardiovascular Disorders.

8 Jun 2007