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Scientists find last unknown enzyme in the synthesis of vitamin C in plants

Vitamin C is possibly the most important small molecule whose biosynthetic pathway remained a mystery.

30 Apr 2007

Schering-Plough announces European approval of new formulations of AERIUS (Desloratadine)

European Commission approves AERIUS Tablets (2.5 mg and 5 mg) and AERIUS Oral Solution (0.5 mg per 1ml).

30 Apr 2007

The convergence of embryonic and cancer signaling pathways: role in tumor cell plasticity

In earlier work, Northwestern University scientist Mary J.C. Hendrix and colleagues discovered that aggressive melanoma cells (but not normal skin cells nor less aggressive melanoma cells) contain specific proteins similar to those found in embryonic stem cells.

30 Apr 2007

Researchers identify antioxidant mechanisms involved in protection against heart disease

Zvonimir Katusic, M.D., Ph.D., and Mayo colleagues have identified antioxidant mechanisms essential for regenerative function of endothelial progenitor cells (EPCs).

30 Apr 2007

Lipocalin-2 protein may hold key to decreasing organ dysfunction rates in heart transplants

A new study, led by Felix Aigner, M.D., has identified a protein known as Lipocalin-2 (Lcn-2) as potentially responsible for regulating the body's inflammatory response during heart transplants.

30 Apr 2007

Cellular protein found that interferes with hepatitis C virus replication

Biomedical researchers have identified a cellular protein that interferes with hepatitis C virus replication, a finding that ultimately may help scientists develop new drugs to fight the virus.

30 Apr 2007

Proportion of uninsured residents in North Carolina increases

The percentage of North Carolinians under the age of 65 who lacked health insurance for a year has risen from 15.3 percent in 2000 to 17.2 percent in 2005.

30 Apr 2007

Nanotechnology shows potential for dental procedures

The mouth is a tough environment, which is why dentists do not give lifetime guarantees.

30 Apr 2007

Many NYC pharmacies fail to cater for people with poor English

Despite widespread capacity to provide prescription medication labels in languages other than English, few New York City pharmacies do so and as a result, limited-English patients face serious risk of medication error, according to a study by The New York Academy of Medicine presented at the annual meeting of the Society for General Internal Medicine (SGIM) in Toronto, Ontario.

30 Apr 2007

Benzylpiperazine a 'new drug of abuse'

Professor Alison Jones said benzylpiperazine was a ,new drug of abuse, which could have serious clinical effects - similar to those of ecstasy to which it is structurally related.

30 Apr 2007

Mail 'shot' helps reduce binge drinking

Mailing a simple information pamphlet to interested drinkers in the general population reduced binge drinking by 10 per cent, and is a promising public health approach to reduce the health and social problems associated with heavy drinking, shows a new study led by the University of Alberta.

30 Apr 2007

INVEGA granted positive opinion recommending approval in Europe

Janssen-Cilag International NV has announced that the Committee for Human Medicinal Products (CHMP) in the European Union, has granted a positive opinion recommending approval of INVEGA (paliperidone prolonged release tablets).

30 Apr 2007

Green tea may help prevent bone destruction in arthritis

In rheumatoid arthritis, a person's own immune system attacks the joints by activating the synovial tissue that lines the body's movable joints, causing inflammation, swelling, pain and eventually erosion of the bone and cartilage and deformation of the joint.

30 Apr 2007

Feasible to create a stockpile of H5N1 vaccine

Countries and vaccine manufacturers agreed on Wednesday in a meeting at WHO that it may be feasible to create a stockpile of H5N1 vaccine, and to separately develop a mechanism to ensure broader access to pandemic influenza vaccine for developing countries in the advent of a pandemic.

30 Apr 2007

Resistance training gets employees with rotator cuff injuries back to work

Resistance training, some of it job-specific, was successful in getting 90 percent of workers with severe rotator cuff injuries back to work, the majority (75 percent) at their previous job, after traditional physical therapy had failed to do so.

30 Apr 2007

FDA approves INVEGA treatment for schizophrenia

The U.S. Food and Drug Administration (FDA) has approved INVEGA (paliperidone) Extended-Release Tablets, a new once-daily, atypical antipsychotic, for the long-term maintenance treatment of schizophrenia.

30 Apr 2007

FDA approves new treatment for von Willebrand disease

The U.S. Food and Drug Administration (FDA) has approved Humate-P (Antihemophilic Factor/von Willebrand Factor Complex) for the prevention of excessive bleeding during and after surgery in certain patients with mild to moderate and severe von Willebrand disease (vWD).

30 Apr 2007

Leptin shown to significantly influence breast cancer development

Being obese increases the risk of breast cancer in post-menopausal women, shortens the time between return of the disease and lowers overall survival rates.

30 Apr 2007

Anti-reflux valve improves quality of life for cancer patients

An anti-reflux valve developed to help esophageal cancer patients also has been shown to help those with bile duct obstruction, according to Kulwinder S. Dua, M.D., a research physician at the Medical College of Wisconsin in Milwaukee.

30 Apr 2007

Environment rich in sensory stimuli restores memory in mice with neurodegeneration

Mice whose brains had lost a large number of neurons due to neurodegeneration regained long-term memories and the ability to learn after their surroundings were enriched with toys and other sensory stimuli, according to new studies by Howard Hughes Medical Institute researchers.

30 Apr 2007