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Microfluidics gives boost to protein crystallization

Proteins produced by cancer cells are among the common targets for anticancer agents, and thanks to efforts in proteomics and cancer genomics, the number of potential protein targets is increasing exponentially.

16 Jan 2007

Nanoparticles yield delivery tools for therapeutic nucleic acids

Cancer researchers hold great hope that nucleic acid-based therapeutics, such as anticancer genes, antisense oligonucleotides, and small interfering RNA (siRNA) molecules, will prove to be powerful antitumor agents.

16 Jan 2007

Biomimetic amplification of nanoparticle homing to tumors

A collaborative, multidisciplinary team of researchers has created nanoparticles that act much like a developing clot to target tumors.

16 Jan 2007

Selective marker found to indicate aggressive form of breast cancer

Researchers have linked a structural protein called nestin to a particularly deadly form of breast cancer, identifying a new biomarker that could lead to earlier detection and better treatment.

16 Jan 2007

Lung neutrophils produce histamine in significant quantities

In a surprise finding, scientists have discovered that histamine, the inflammatory compound released during allergic reactions that causes runny nose, watery eyes, and wheezing, can be produced in large amounts in the lung by neutrophils, the white blood cells that are the major component of pus.

14 Jan 2007

Fibrinogen molecule structure acts as a molecular spring

Researchers at the University of Pennsylvania School of Medicine and the School of Arts and Sciences have shown that a well-known protein structure acts as a molecular spring, explaining one way that clots may stretch and bend under such physical stresses as blood flow.

14 Jan 2007

Variations in SORL1 gene may factor in development of Alzheimer's disease

Variations in a gene known as SORL1 may be a factor in the development of late onset Alzheimer's disease, an international team of researchers has discovered. The genetic clue, which could lead to a better understanding of one cause of Alzheimer's, is reported in Nature Genetics online, and was supported in part by the National Institutes of Health (NIH).

14 Jan 2007

Stem cell research discovery could mean 'big things' for cancer

A new discovery in stem cell research may mean big things for cancer patients in the future. Gary Van Zant, Ph.D., and a research team at the University of Kentucky published their findings in Nature Genetics.

14 Jan 2007

Bristol-Myers Squibb and AstraZeneca to collaborate on Type 2 diabetes compunds

Bristol-Myers Squibb and AstraZeneca have announced a collaboration to develop and commercialize two investigational compounds being studied for the treatment of Type 2 diabetes. Both compounds were discovered by Bristol-Myers Squibb.

14 Jan 2007

Lilly to change global manufacturing operations

Eli Lilly and Company has announced several strategic changes to its global manufacturing operations to better support the company's current product portfolio and evolving drug pipeline.

14 Jan 2007

Race to accelerate tuberculosis drug development

Each year, tuberculosis kills nearly two million people while an estimated nine million develop the disease -- with the hardest-hit areas in AIDS-afflicted developing nations.

14 Jan 2007

Men with short telomeres may have a greater risk for heart disease

Men with short telomeres - repetitive strips of DNA that cap the ends of chromosomes - may have a higher risk of developing coronary heart disease than those with long telomeres, according to an Article in this week's issue of The Lancet.

14 Jan 2007

In Vitro diagnostic market in Europe

The latest estimates on the In Vitro Diagnostic (IVD) market in Europe, corresponding to the year 2005, are now available.

14 Jan 2007

Hospital death rate study reveals wide variations and stresses importance of Registered Nurses

Hospital death rates can be reduced by employing more Registered Nurses and the routine use of care maps or protocols, according to a study in the latest UK-based Journal of Advanced Nursing.

14 Jan 2007

New study examines the influence and impact of conspiracy theories surrounding the death of Princess Diana

In their forthcoming paper, "The hidden impact of conspiracy theories: Perceived and actual influence of theories surrounding the death of Princess Diana", Dr Karen Douglas and Dr Robbie Sutton from the University of Kent show that people are persuaded by conspiracy theories about Princess Diana’s death even though they do not necessarily know it.

14 Jan 2007