Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

UT Southwestern researchers develop new imaging method to see proteins in action

UT Southwestern Medical Center researchers developed a new imaging technique that makes X-ray images of proteins as they move in response to electric field pulses.

16 Dec 2016

Fully automated live cell imaging and analysis from BioTek’s BioSpa

BioTek’s BioSpa Live Cell Imaging System fully automates live cell imaging workflows for robust, real-time results without the need for manual intervention.

12 Dec 2016

Musica Humana: Innovative program highlights inspiring role of music in human thought and memory

According to renowned neurologist Oliver Sacks, "music can move us to the heights or depths of emotion, but the power of music goes much further."

9 Dec 2016

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

ABIVAX an innovative biotechnology company targeting the immune system to eliminate viral disease, announced today that the Company presented new preclinical data on ABX464, ABIVAX's first-in-class drug candidate for a functional cure of patients with HIV/AIDS, during this week's HIV DART scientific conference in Los Cabos, Mexico.

9 Dec 2016

Research findings could pave way for synthesis of biologically active oligopeptides

The research community and pharmaceutical industry have had a long-standing interest in developing peptide-based therapeutics owing to their high target specificity, potent activity, and small size relative to protein-based biologics.

9 Dec 2016

AstraZeneca introduces world’s most advanced drug discovery robot

AstraZeneca entered a new era in drug development today by unveiling NiCoLA-B, the world’s most advanced drug discovery robot, capable of performing experiments at an industrial scale in the search for new, life-saving medicines.

8 Dec 2016

Synthetic sgRNA for CRISPR genome editing

Chemically synthesized single guide RNA is the best way to do CRISPR genome editing. It is more pure than biological methods of creating guide RNAs, like in vitro transcription or plasmids. As a result, sgRNA leads to more consistency and higher quality.

8 Dec 2016

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine.

7 Dec 2016

Researchers identify critical paralog groups with indispensable role in cellular signalling pathways

Throughout evolutionary history, there have been genetic elements that have duplicated - giving rise to genes with different functions.

7 Dec 2016

Study reveals new way to improve stability of common protein drugs

Gaining access to important biopharmaceuticals needed to treat illnesses and autoimmune diseases is one of the biggest obstacles developing countries face.

2 Dec 2016

Monell Center receives Gates Foundation grant to support innovative global health research project

The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays."

1 Dec 2016

IUPUI scientists develop new synthetic method to shorten drug discovery and development process

Synthesizing useful new compounds is what pharmaceutical discovery and development is all about. Researchers at the School of Science at Indiana University-Purdue University Indianapolis have devised a method to substantially speed up the process.

1 Dec 2016

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity.

30 Nov 2016

New appointment to accelerate discovery of patient-centred medicines

The new Medicines Discovery Catapult (MDC) is pleased to announce the appointment of Ed Owen to put medical research charities and patient groups at the heart of the development of new therapies in the UK.

29 Nov 2016

Dilon and GE receive FDA approval for Discovery NM750b breast imaging system

DILON Diagnostics and GE Healthcare are pleased to announce the FDA clearance of the Molecular Breast Imaging (MBI) localization accessory for breast biopsy.

26 Nov 2016

De-risking drug development free webinar from Envigo

De-risking represents a relatively new but developing strategy designed to quickly assess if a new drug has a liability. Knowing your compound’s risk for drug-to-drug interactions (DDI), drug induced liver injury (DILI) and metabolites in safety testing (MIST) early on in drug development, leads to greater confidence and added value on your molecule’s journey to market.

18 Nov 2016

DILON Diagnostics to distribute GE's Discovery NM750b breast imaging system in North America

DILON Diagnostics and GE Healthcare are pleased to announce that they have signed an agreement for DILON to be the exclusive distributor of GE's Discovery NM750b Molecular Breast Imaging system in North America.

16 Nov 2016

Research shows CRAC channel inhibitors decrease lesion size, brain hemorrhage, and neurological deficits in TBI model

Researchers from the San Francisco Veterans Affairs Medical Center and UCSF, and CalciMedica, Inc., are presenting a poster at the 46th annual Society for Neuroscience meeting in San Diego describing the use of calcium release-activated calcium (CRAC) channel inhibitors in traumatic brain injury (TBI).

16 Nov 2016

Researcher investigating drugs to prevent lung cancer from spreading

The American Cancer Society has reported that lung cancer, which kills more Americans than any other type of cancer, is expected result in an estimated 158,080 deaths in 2016.

11 Nov 2016

New discovery may lead to better treatment options for pancreatic cancer patients

Pancreatic cancer, the third leading cause of cancer-related deaths, is projected to be the second by the year 2030, according to a study in the journal of Cancer Research.

11 Nov 2016

Drug Discovery News and Research

Further Reading

UT Southwestern researchers develop new imaging method to see proteins in action

Fully automated live cell imaging and analysis from BioTek’s BioSpa

Musica Humana: Innovative program highlights inspiring role of music in human thought and memory

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

Research findings could pave way for synthesis of biologically active oligopeptides

AstraZeneca introduces world’s most advanced drug discovery robot

Synthetic sgRNA for CRISPR genome editing

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Researchers identify critical paralog groups with indispensable role in cellular signalling pathways

Study reveals new way to improve stability of common protein drugs

Monell Center receives Gates Foundation grant to support innovative global health research project

IUPUI scientists develop new synthetic method to shorten drug discovery and development process

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

New appointment to accelerate discovery of patient-centred medicines

Dilon and GE receive FDA approval for Discovery NM750b breast imaging system

De-risking drug development free webinar from Envigo

DILON Diagnostics to distribute GE's Discovery NM750b breast imaging system in North America

Research shows CRAC channel inhibitors decrease lesion size, brain hemorrhage, and neurological deficits in TBI model

Researcher investigating drugs to prevent lung cancer from spreading

New discovery may lead to better treatment options for pancreatic cancer patients

ELRIG Drug Discovery: Poster Sessions eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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