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European approval for Taxotere (docetaxel) in prostate cancer

Aventis, part of the sanofi-aventis Group announced today that the European Commission has approved Taxotere (docetaxel) Injection Concentrate for use in combination with prednisone as a treatment for men with androgen-independent (hormone- refractory) metastatic prostate cancer.

4 Nov 2004

Wyeth shows new Phase III data about its investigational antibiotic, tigecycline

Wyeth Pharmaceuticals recently presented exciting new Phase III data about its investigational antibiotic, tigecycline, based on a clinical trial in patients with complicated intra-abdominal infections (cIAI).

4 Nov 2004

Peripheral blood transplants from donors may be more harmful than bone marrow transplants in pediatric leukemia patients

A new study has shown for the first time that transplantation of peripheral blood stem cells (PBSC) from sibling donors may be more harmful than bone marrow in pediatric leukemia patients.

3 Nov 2004

Analysis shows Remicade reduces pain associated with Crohn's disease

According to a new sub-analysis from the ACCENT I (A Crohn's disease Clinical trial Evaluating infliximab in a New long-term Treatment regimen) trial patients who received a three-dose induction regimen of Remicade experienced a significantly greater reduction in pain as assessed by four different pain questions after ten weeks, compared with patients who received a single dose of Remicade.

2 Nov 2004

Maxim Pharmaceuticals to withdraw NDA for advanced malignant melanoma

Maxim Pharmaceuticals has announced that based upon the negative outcome of it's confirmatory Phase 3 clinical trial (M0104) studying Ceplene(TM) (histamine dihydrochloride) in combination with Interleukin-2 (IL-2) in advanced malignant melanoma patients with liver metastases, it plans to close the treatment protocol approved by the FDA earlier this year.

2 Nov 2004

High-dose statin therapy for aggressive cholesterol-lowering outperforms typical care

Patients treated with high doses of atorvastatin had about a one percent lower annual rate of heart attacks than similar patients receiving usual care, according to a new study in the Nov. 2, 2004 issue of the Journal of the American College of Cardiology.

2 Nov 2004

Possible treatment for the fatal lung disease idiopathic pulmonary fibrosis

They found that the anti-cancer drug imatinib mesylate — commercially known as Gleevec and produced by Novartis Pharmaceuticals — can target a gene critical to controlling the disease process. Previously, there had been no treatment and patients usually did not survive beyond three years of diagnosis. Now the treatment is undergoing clinical trials at Mayo Clinic.

2 Nov 2004

Clinical trial of investigational oxygen-carrying blood substitute for use at the scene of injury

Loyola University Health System begins today the national clinical trial using PolyHeme®, an investigational oxygen-carrying blood substitute designed to increase survival of critically injured and bleeding trauma patients at the scene of injury.

1 Nov 2004

Improved risk classification for patients with acute lymphoblastic leukemia offers hope for eliminating irradiation

Improved risk classification for patients with acute lymphoblastic leukemia (ALL), coupled with more intensive intrathecal chemotherapy for high risk patients and the use of a drug called dexamethasone, could one day permit physicians to omit irradiation as a part of routine treatment.

1 Nov 2004

New approaches for the treatment of chronic hepatitis C

Data from two ongoing studies testing new approaches for the treatment of chronic hepatitis C was presented at the annual meeting of the American Association for the Study of Liver Diseases (AASLD) this afternoon.

1 Nov 2004

New treatment option for patients who have moderately active ulcerative colitis

Results of a study presented today by a Mayo Clinic physician at the 69th Annual Scientific Meeting of the American College of Gastroenterology (ACG) in Orlando, Fla., offer a new treatment option for patients who have moderately active ulcerative colitis.

1 Nov 2004

Brain imaging technology shows how the adult dyslexic brain can change

New findings from researchers at Georgetown University Medical Center in collaboration with Wake Forest University School of Medicine have shown that there is hope for individuals suffering a life-long history of reading problems.

1 Nov 2004

Alimta approved as first treatment for Mesothelioma, a deadly cancer caused by asbestos

Lilly UK announced today that Alimta( (pemetrexed) will be available shortly for the treatment of people diagnosed with mesothelioma, a cancer of the lining of the lungs for which there is no known cure. Pemetrexed is the first licenced treatment for malignant pleural mesothelioma, in combination with cisplatin.

1 Nov 2004

Brief psychological interventions are effective in relieving traumatic stress symptoms in family members

Family therapy and other psychological treatments may help reduce symptoms of post-traumatic stress among teenaged survivors of childhood cancer--as well as among their parents.

28 Oct 2004

Ruboxistaurin may reduce vision loss from diabetes-induced eye disease

Eli Lilly and Company's investigational compound ruboxistaurin may reduce vision loss from diabetes-induced eye disease, according to new analyses of previously reported data presented at the 2004 Joint Meeting of the American Academy of Ophthalmology and the European Society of Ophthalmology in New Orleans, La.

26 Oct 2004

Researchers are comparing two drugs used to treat pediatric bipolar disorder

University of Illinois at Chicago researchers are comparing two drugs used to treat pediatric bipolar disorder patients to evaluate how the drugs affect brain function in children with the disorder.

25 Oct 2004

Why some anesthesiologists end up abusing drugs

University of Florida researchers have presented a new theory at the 34th annual Society for Neuroscience on why some anesthesiologists end up abusing drugs.

25 Oct 2004

MedImmune initiates clinical trial comparing intranasal influenza vaccine with injectable flu vaccine

MedImmune announced that it has initiated a pivotal head-to-head Phase 3 clinical trial designed to compare its next-generation, refrigerator- stable intranasal influenza vaccine (CAIV-T: cold adapted intranasal influenza vaccine, trivalent) with the injectable flu shot (TIV: trivalent influenza vaccine).

22 Oct 2004

New antibody to prevent respiratory syncytial virus in premature babies

Virginia Commonwealth University researchers are studying the effectiveness of introducing a new antibody in premature infants to manage the most common form of lower respiratory tract infections in children worldwide.

21 Oct 2004

Insulin pumps effective for children with diabetes

Pre-school youngsters with type I diabetes can be treated as successfully with insulin pumps as with daily injections, researchers at the Indiana University School of Medicine report.

18 Oct 2004

Clinical Trial News and Research

European approval for Taxotere (docetaxel) in prostate cancer

Wyeth shows new Phase III data about its investigational antibiotic, tigecycline

Peripheral blood transplants from donors may be more harmful than bone marrow transplants in pediatric leukemia patients

Analysis shows Remicade reduces pain associated with Crohn's disease

Maxim Pharmaceuticals to withdraw NDA for advanced malignant melanoma

High-dose statin therapy for aggressive cholesterol-lowering outperforms typical care

Possible treatment for the fatal lung disease idiopathic pulmonary fibrosis

Clinical trial of investigational oxygen-carrying blood substitute for use at the scene of injury

Improved risk classification for patients with acute lymphoblastic leukemia offers hope for eliminating irradiation

New approaches for the treatment of chronic hepatitis C

New treatment option for patients who have moderately active ulcerative colitis

Brain imaging technology shows how the adult dyslexic brain can change

Alimta approved as first treatment for Mesothelioma, a deadly cancer caused by asbestos

Brief psychological interventions are effective in relieving traumatic stress symptoms in family members

Ruboxistaurin may reduce vision loss from diabetes-induced eye disease

Researchers are comparing two drugs used to treat pediatric bipolar disorder

Why some anesthesiologists end up abusing drugs

MedImmune initiates clinical trial comparing intranasal influenza vaccine with injectable flu vaccine

New antibody to prevent respiratory syncytial virus in premature babies

Insulin pumps effective for children with diabetes

eBook: Using iPSCs models for human disease research and drug discovery eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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