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Three-dimensional ultrasound probes poised to advance minimally invasive surgery

Three-dimensional ultrasound probes built by researchers at Duke's Pratt School of Engineering have imaged the beating hearts of dogs. The engineers said their demonstration showed that the probes could give surgeons a better view during human endoscopic surgeries in which operations are performed through tiny "keyhole" incisions.

4 Apr 2006

Majority of young people with ADHD use their medications appropriately

A major concern regarding the use of stimulant medications to treat attention-deficit hyperactivity disorder (ADHD) in adolescents and young adults has been the risk that they will be misused or diverted to those for whom they have not been prescribed.

4 Apr 2006

Skin cancer facts

Up to two-thirds of all cancers may be prevented through dietary and lifestyle changes. In the case of skin cancer, this could not be more true.

4 Apr 2006

Pigs help study of links between polycystic ovary syndrome, obesity, cardiovascular disease and diabetes

Despite the exaggerated, wrinkly snout and long, coarse, spiky hair reminiscent of the 1980s television space alien ALF, some very special swine are helping researchers at Purdue and Indiana universities understand human infertility, diabetes and cardiovascular disease.

4 Apr 2006

HOXB13 and IL17BR genes predict outcome for breast cancer patients

The 2-gene expression profile of HOXB13 and IL17BR in a woman's breast cancer predicts risk of recurrence in node-negative patients treated with tamoxifen.

4 Apr 2006

Mayo Clinic discover cellular secret that may explain how certain cancers move and spread

If the mechanism that drives cancer movement - also called metastasis - can be understood well enough to manipulate it, new and better treatments can be developed for patients with metastatic cancers.

4 Apr 2006

Antioxidant therapy will be useful for women with pre-eclampsia

The antioxidant tempol prevents the onset of pre-eclampsia in pregnant mice, a finding that further implicates oxidative stress in the illness, which is widespread among pregnant women.

4 Apr 2006

Enzymes that harm brain immediately after stroke may be beneficial days later

Insights from the study could change the way stroke is treated, extending the window for effective treatment from a couple of hours to a couple of weeks. The results may suggest new ideas for drug development.

4 Apr 2006

New mouse model technology in cancer vaccine tool-box

Cancer vaccines are being investigated in early-phase clinical trials around the world, with many of those trials recruiting patients with melanoma.

4 Apr 2006

Link between lead and osteoporosis strengthens

Bolstered by recent laboratory findings, researchers at the University of Rochester Medical Center are embarking on a National Institutes of Health-funded clinical study to better understand the deceptive role environmental lead exposure plays in bone maturation and loss.

4 Apr 2006

Targeting the inflamed synovium: The quest for specificity

In the April 2006 issue of Arthritis & Rheumatism, noted rheumatology specialists with Kings College London, Dr. Toby Garrood and Dr. Costantino Pitzalis offer an overview of recent breakthroughs and a preview of future directions in this critical quest for specificity.

4 Apr 2006

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis

Inflammation, cartilage and bone erosions, joint destruction--that's the typical progression of arthritis and most rheumatic diseases.

4 Apr 2006

Targeting of angiogenic endothelial cells at sites of inflammation by Dexamethasone Phosphate-containing RGD peptide liposomes inhibits experimental arthritis

Vascular endothelial cells (VECs) form the walls of blood vessels and play a critical role in inflammation.

4 Apr 2006

New clinical trial to test different strengths of a vaccine designed to fight avian influenza

The Duke study is part of a multicenter trial that will test a modified form of an investigational bird flu vaccine to determine whether the vaccine still triggers a strong immune response at lower doses.

4 Apr 2006

Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheep

While newly published research confirms that under laboratory circumstances prion-protein can be absorbed across the gut, it also shows that this is unlikely to occur in real life.

4 Apr 2006

Life or death can depend on teenage cancer patients taking their treatments properly

Teenagers and young adults with cancer need to understand the implications of not taking their treatments regularly, at the right time, and for the whole course. Those who don't are seriously compromising their future health - and for some it will be the difference between life and death.

4 Apr 2006

Natural killer cells and antibody-based immune function

A new drug may boost the effectiveness of a widely used treatment for patients with non-Hodgkin lymphoma (NHL), while simultaneously overcoming drug resistance in those patients.

4 Apr 2006

Immune response protects against brain tumor development

In their quest to determine whether immune system surveillance guards against brain tumor development, researchers at The University of Texas M. D. Anderson Cancer Center have found that allergies and asthma that stimulate inflammation may be protective, but use of antihistamines to control the inflammation could eliminate that protection.

4 Apr 2006

New biomarkers could help detect ovarian cancer much earlier

The search for a specific protein that could help diagnose ovarian cancer in its early stages has for years eluded researchers who are seeking a reliable and accurate test for the disease.

4 Apr 2006

Study demonstrates the importance of familial factors in the general development of cancer

Studying thousands of people, researchers at The University of Texas M. D. Anderson Cancer Center have documented a 25 percent increased risk of developing one of a number of cancers in first-degree relatives of lung cancer patients who have never smoked compared to families of people who neither smoke nor have lung cancer.

4 Apr 2006

Research News and Research

Three-dimensional ultrasound probes poised to advance minimally invasive surgery

Majority of young people with ADHD use their medications appropriately

Skin cancer facts

Pigs help study of links between polycystic ovary syndrome, obesity, cardiovascular disease and diabetes

HOXB13 and IL17BR genes predict outcome for breast cancer patients

Mayo Clinic discover cellular secret that may explain how certain cancers move and spread

Antioxidant therapy will be useful for women with pre-eclampsia

Enzymes that harm brain immediately after stroke may be beneficial days later

New mouse model technology in cancer vaccine tool-box

Link between lead and osteoporosis strengthens

Targeting the inflamed synovium: The quest for specificity

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis

Targeting of angiogenic endothelial cells at sites of inflammation by Dexamethasone Phosphate-containing RGD peptide liposomes inhibits experimental arthritis

New clinical trial to test different strengths of a vaccine designed to fight avian influenza

Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheep

Life or death can depend on teenage cancer patients taking their treatments properly

Natural killer cells and antibody-based immune function

Immune response protects against brain tumor development

New biomarkers could help detect ovarian cancer much earlier

Study demonstrates the importance of familial factors in the general development of cancer

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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