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Inducing melanoma for cancer vaccine development

Cancer vaccines are being investigated in early-phase clinical trials around the world, with many of those trials recruiting patients with melanoma.

28 Mar 2006

Novel therapy for chronic graft-versus-host disease

A study by Dana-Farber Cancer Institute researchers offers the strongest evidence yet of the effectiveness of a novel therapy for chronic graft-versus-host disease (GVHD), a potentially life-threatening complication of donor bone marrow and stem cell transplants.

28 Mar 2006

Study on fruit flies offers new approach to understand human response to viral infections

A research team led by UC Riverside scientists has shown that the common fruit fly can serve as an excellent model for studying the immunity animals are born with for fighting viral infections.

28 Mar 2006

Patent filed for method to prevent early labor and premature delivery of low-birth-weight babies

The discovery is an incremental step in an area of obstetrics that has seen little improvement in 20 years.

28 Mar 2006

New way of targeting proteins to exosomes - potential for melanoma, Alzheimer's disease

Researchers at the University of Pennsylvania School of Medicine have discovered how a protein called Pmel17 is sorted by pigment cells in the skin and eye to make a fiber matrix that eventually sequesters melanin, the dark pigment found in skin, hair, and eyes.

28 Mar 2006

First trial to combine a biologic agent with a conventional chemotherapy agent for the treatment of ovarian cancer

Researchers found the addition of thalidomide to topotecan for the treatment of recurrent ovarian cancer significantly increases the response to therapy and the duration of progression free survival without additional toxicity.

28 Mar 2006

New information about the molecular pathway used by ubiquitin

Because ubiquitin plays a key role in cell survival, scientists have already begun to develop drugs to target parts of the ubiquitin pathway in treating diseases such as cancer.

28 Mar 2006

Smokers assume false sense of safety from ads for low nicotine cigarettes

A study by researchers at the Transdisciplinary Tobacco Use Research Center of the University of Pennsylvania School of Medicine found that many smokers make false inferences about the safety of new low nicotine Quest cigarettes.

28 Mar 2006

No evidence that early episodes of schizophrenia without medication result in long-term harm

A University of Southern California - USC review of published research has found no evidence that early episodes of schizophrenia without medication result in long-term harm for patients, casting doubt on the practice to immediately medicate for a year.

28 Mar 2006

Mustard and garlic kick linked to single pain receptor

A single pain receptor is solely responsible for the kick delivered by mustard oil and garlic, according to research in the Cell. Mustard oil is the active ingredient in mustard and in the pungent green sushi condiment known as wasabi.

28 Mar 2006

RNAi-based inhibitors for created for nearly every human and mouse gene - available to all genetic researchers

An international public-private research team led by scientists at the Broad Institute of MIT and Harvard announced today the construction and availability of an extensive library of molecular reagents to silence most human and mouse genes.

28 Mar 2006

Ocean Vesivirus found in human blood samples

A virus of ocean origin that can cause a range of diseases in several animal species has been found in human blood samples. The virus, or antibodies to it, was found most often in the blood of individuals with liver damage, or hepatitis of unknown cause related to blood exposure.

28 Mar 2006

Earlier onset of colorectal cancer associated with alcohol use, tobacco use and male gender

Colorectal cancer is the second leading cause of cancer death in the United States yet it is one of the most preventable forms of the disease.

28 Mar 2006

Study shows patients regain hand function when given cortical stimulation with rehab

Sending tiny electric pulses to a part of the brain controlling motor function helps ischemic stroke survivors regain partial use of a weakened hand, new Oregon Health & Science University research shows.

28 Mar 2006

Egyptian program to eliminate elephantiasis successful

Organizers of a 20-year global effort to eliminate a parasitic infection that is a leading cause of disability have an early victory to savor: a five-year Egyptian elimination campaign has mostly succeeded, according to a new report in the March 25 issue of The Lancet.

28 Mar 2006

Procedure cures some diabetic mice, but not in the way previously reported

Researchers attempting to reproduce a controversial 2003 mouse experiment suggestive of a cure for type 1 diabetes have found evidence that the experimental procedure does eliminate diabetic symptoms in a small fraction of the mice exposed to it.

28 Mar 2006

Researchers find environmentally friendly ways to produce more Taxol

As the effective cancer-treatment drug Taxol enters its next generation, Michigan State University announces discoveries which point to both environmentally friendly ways to produce more Taxol, and ultimately innovations to produce a more potent second-generation drug.

28 Mar 2006

Determining the risk of ovarian malignancy in postmenopausal women with abnormal findings in the PLCO screening trial

Reporting on the largest study of its kind today at the Society of Gynecologic Oncologists 37th Annual Meeting on Women's Cancer, researchers presented new criteria for detecting ovarian cancer malignancy in postmenopausal asymptomatic women, 55 to 74 years old.

28 Mar 2006

Depression treatment may require different drugs for different people

If a first antidepressant medication doesn't work, try a different one, UT Southwestern Medical Center researchers report.

27 Mar 2006

Substantial protection from coronary heart disease given by lowering cholesterol earlier in life

New research from UT Southwestern Medical Center indicates that lowering "bad" blood cholesterol earlier in life, even by a modest amount, confers substantial protection from coronary heart disease.

27 Mar 2006

Research News and Research

Inducing melanoma for cancer vaccine development

Novel therapy for chronic graft-versus-host disease

Study on fruit flies offers new approach to understand human response to viral infections

Patent filed for method to prevent early labor and premature delivery of low-birth-weight babies

New way of targeting proteins to exosomes - potential for melanoma, Alzheimer's disease

First trial to combine a biologic agent with a conventional chemotherapy agent for the treatment of ovarian cancer

New information about the molecular pathway used by ubiquitin

Smokers assume false sense of safety from ads for low nicotine cigarettes

No evidence that early episodes of schizophrenia without medication result in long-term harm

Mustard and garlic kick linked to single pain receptor

RNAi-based inhibitors for created for nearly every human and mouse gene - available to all genetic researchers

Ocean Vesivirus found in human blood samples

Earlier onset of colorectal cancer associated with alcohol use, tobacco use and male gender

Study shows patients regain hand function when given cortical stimulation with rehab

Egyptian program to eliminate elephantiasis successful

Procedure cures some diabetic mice, but not in the way previously reported

Researchers find environmentally friendly ways to produce more Taxol

Determining the risk of ovarian malignancy in postmenopausal women with abnormal findings in the PLCO screening trial

Depression treatment may require different drugs for different people

Substantial protection from coronary heart disease given by lowering cholesterol earlier in life

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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