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Genetic switch that turns off an oxygen-poor cell's combustion engine - finding has potential to limit toxic molecules

Johns Hopkins researchers have discovered a previously unrecognized role played by the gene HIF-1 as it helps cell survive when a lack of oxygen decreases production of an energy-rich molecule called ATP and increases production of toxic molecules.

9 Mar 2006

New genome-wide map of miRNA-MRNA interactions

Researchers at New York University's Center for Comparative Functional Genomics and the University of California, Berkeley have used computational analyses to predict a genome-wide map of microRNA (miRNA) targets in the animal model organism, Caenorhabditis elegans (C. elegans).

9 Mar 2006

How mammalian brains recognize other individuals

Imagine seeing a former high school classmate you always wanted to know better. Then imagine seeing that kid who used to push you in the hallways. Do you react differently? What happens in your brain during these encounters?

9 Mar 2006

Sex chromosome genes influence aggression

It has been well documented that, across human cultures and in most mammals, males are usually more aggressive and less nurturing than females.

9 Mar 2006

Father-daughter inbreeding avoidance in a wild primate population

A 14 year behavioral and genetic study of a population of wild capuchin monkeys has shown that fathers almost never mate with their daughters, even though alpha males sire the majority of offspring produced by females unrelated to them.

9 Mar 2006

ATF2 protein may play a crucial role in cancer's ability to resist chemotherapy and radiation treatment

Researchers at Purdue University have discovered a molecular mechanism that may play a crucial role in cancer's ability to resist chemotherapy and radiation treatment and that also may be involved in Alzheimer's and heart disease.

9 Mar 2006

Novel compound may help fight obesity

A new study reveals an attractive new target for therapies aimed at the treatment of obesity and related metabolic disorders, researchers report in the March Cell Metabolism.

9 Mar 2006

Information sharing crucial to healthcare

Much has been written about the enormous effort required to take scientific discovery from the laboratory bench to the patient's bedside.

9 Mar 2006

Drug shortfall as more than 5,000 conditions need medication

Only seven per cent of drug applications for treating people with rare diseases were approved in Europe between 2000 and 2004, despite the fact that there are currently more than 5,000 conditions needing medication.

9 Mar 2006

Soy protein, almonds, plant sterol enriched margarines, oats and barley among most effective cholesterol-lowering foods

Cholesterol-lowering foods such as soy protein, almonds, plant sterol enriched margarines, oats and barley may reduce cholesterol levels more effectively when eaten in combination, says a new University of Toronto study by Professor David Jenkins.

9 Mar 2006

Pregnancy diet has lifelong effects for baby

University of Nottingham researchers are targeting Europe's biggest killer diseases - by focusing on the diet of unborn babies.

8 Mar 2006

Inflammation is a crucial and dangerous step in the development of obesity

New research by the University of Warwick's Warwick Medical School shows that the biggest health threat to fat and obese people isn't the fat itself but the fact that the fat fuels a killer inflammation response in people.

8 Mar 2006

Third of adults are lonely!

More than a third of adults are lonely, with people in their forties suffering the highest levels, according to a study published in the latest Journal of Clinical Nursing.

8 Mar 2006

Major biomarker candidates for Alzheimer's disease explored

Alzheimer's disease - specific biomarkers clearly are needed for the differential diagnosis of cognitive impairment in the elderly.

8 Mar 2006

Scientists fight leukaemia with 'natural killer' cells

Scientists at the University of the West of England and the Bone Marrow Transplant Unit at the Bristol Children's Hospital have just won funding for a two-year project aimed at improving the outcome of bone marrow stem-cell transplants in young leukaemia patients.

8 Mar 2006

Relationship between periodonta treatment and overall cost of care for several diseases

Chronic conditions such as diabetes mellitus (DM), coronary artery disease (CAD), and cerebrovascular disease (CVD) have been associated with periodontal disease.

8 Mar 2006

Short-term exposure to fine particulate matter increases hospital admissions for heart problems

Short-term exposure to fine particulate matter - the microscopic particles that pollute the air - increased hospital admissions for cardiovascular and respiratory disease among Medicare participants, according to a study of 204 U.S. urban counties conducted by researchers at the Johns Hopkins Bloomberg School of Public Health and Yale University’s environment school.

8 Mar 2006

Bottle-fed babies more likely to be obese children

The objective of the research, which was based on the detailed feeding history of almost 900 mothers and babies in the Avon Longitudinal Study of Parents and Children, was to find out whether different feeding patterns and energy intakes provided to infants, affected body weight and BMI later in childhood.

8 Mar 2006

Revatio now available in the UK

Patients in the UK suffering from a rare life-threatening heart condition, pulmonary arterial hypertension (PAH), could soon be offered a new treatment.

8 Mar 2006

Troubling increase in repeat cesarean delivery

A survey conducted to determine the basis for the increased number of repeat cesarean births in the United States found that nearly 10 percent of women had undocumented reasons for the surgery.

8 Mar 2006