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New system for analyzing how drugs bind to proteins

Researchers at Florida State University's National High Magnetic Field Laboratory and Scripps Florida have developed and evaluated a robust new system for analyzing how drugs bind to proteins. This groundbreaking work could speed the delivery of potential new drugs and improve existing ones.

19 Feb 2006

Mystery of evolutionary growth in hominid brain size

Forget the textbook story about tool use and language sparking the dramatic evolutionary growth of the human brain. Instead, imagine ancient hominid children chasing frogs. Not for fun, but for food.

19 Feb 2006

Snogging quadruples risk of meningitis in teenagers

Intimate kissing with multiple partners almost quadruples a teenager's risk of meningococcal disease, finds a study published online by the British Medical Journal.

19 Feb 2006

Monoclonal antibody targets key tumor growth factor

Monoclonal antibody targets key tumor growth factor; Successfully causes brain tumor regression and improves animal survival

19 Feb 2006

Organic diets lower children's exposure to pesticides

Organic diets lower children's dietary exposure to two common pesticides used in U.S. agricultural production, according to a study by Emory University researcher Chensheng "Alex" Lu, PhD. The substitution of organic food items for children's normal diets substantially decreased the pesticide concentration to non-detectable levels.

19 Feb 2006

Pig islets successfully reversed diabetes in monkeys

Researchers at the University of Minnesota's Diabetes Institute for Immunology and Transplantation have successfully reversed diabetes in monkeys using transplanted islet cells from pigs.

19 Feb 2006

Science of autism

As theories about autism spread like wildfire in the media and the general public, a panel of autism experts will reflect on the validity of four widely held - and potentially inaccurate - assumptions about the developmental disability.

19 Feb 2006

Estrogen-progestin menopausal hormone therapy associated with high risk of both lobular and tubular breast cancer

Estrogen-progestin menopausal hormone therapy is associated with a more than two-fold higher relative risk of developing lobular cancer or tubular cancer than of developing ductal cancer.

19 Feb 2006

Blood clot warning to go on Ortho Evra birth control patch

The U.S. Food and Drug Administration (FDA) says early results of a new study show that women who use the Ortho Evra contraceptive patch are twice as likely to develop blood clots than others who took a birth control pill.

19 Feb 2006

Protein levels predict bone marrow transplant survival

Researchers say that protein levels can predict which bone marrow transplant patients are likely develop a deadly complication a week after the procedure and well before any symptoms occur.

19 Feb 2006

Children given lower doses of adult drugs at risk of harmful side effects

A new study has provided the strongest and most comprehensive evidence yet of the difference between how adults and infants and children process drugs.

19 Feb 2006

Bathroom scale model of weight loss most effective

According to a researcher in the U.S. losing and keeping off weight requires a lifelong commitment and effort.

19 Feb 2006

Puberty means girls more at risk of insomnia than boys

According to a new U.S. study of 1014 adolescents who were 13 to 16 years of age, almost 11 percent had suffered from insomnia at some stage.

19 Feb 2006

Cathepsin inhibitors as cancer therapies

In the March 1 issue, Drs. Johanna Joyce (MSKCC), Douglas Hanahan (UCSF) and colleagues lend new insight into how broad-spectrum cysteine cathepsin inhibitors combat pancreatic cancer, and provide new data to help refine the design of more precisely targeted anti-cathepsin therapies.

17 Feb 2006

Poor physical fitness associated with lower socioeconomic status and higher rate of death

Individuals who have abnormal findings on exercise stress testing are more likely to have lower than higher socioeconomic status, and these physiologic characteristics may help account for the correlation between low SES and a higher rate of death

17 Feb 2006

Topical anaesthesia and morphine effective in treating procedural pain in newborn infants

Researchers at The Hospital for Sick Children (SickKids) have found that intravenous morphine used alone or with a topical anaesthetic (tetracaine) effectively reduced levels of pain in newborn infants undergoing insertion of central venous catheters (central lines).

17 Feb 2006

GeneDesign speeds design of artificial pieces of DNA

Johns Hopkins researchers have announced the development of a Web-based, automated computer program that they say greatly simplifies the time-consuming and error-prone process of manually designing artificial pieces of DNA.

17 Feb 2006

Hospitalization of a spouse can harm the wellbeing of his or her partner

In the largest study ever to quantify caregiver burden and the widower effect, researchers found that for people aged 65 and older, hospitalization of a spouse can harm the wellbeing of his or her partner and significantly contribute to that partner's death.

17 Feb 2006

Ovarian cancer responds to aspirin and chemotherapy drug cisplatin

A new study using ovarian cancer cell lines shows promise in treating the deadly disease by combining the chemotherapy drug cisplatin with an aspirin-like compound to make recurrent cancer cells less resistant to the chemotherapy.

17 Feb 2006

Unexpected rheumatoid arthritis discovery

What makes joints in people with rheumatoid arthritis, and related conditions like Lyme disease or lupus, so susceptible to attack by the body's immune system, leading to painful flare-ups and deterioration? The answer may surprise you.

17 Feb 2006