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Research suggests that a common mechanism may underlie a variety of protein folding diseases

Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease.

16 Feb 2006

Macrophage signaling may affect hormone resistance in prostate tumors

Interaction between prostate cancer cells and immune cells called macrophages may be a source of inflammatory signals capable of impacting the effectiveness of androgen antagonists, the most common and effective treatment for prostate cancer, according to a new study by researchers at the University of California, San Diego (UCSD) School of Medicine.

16 Feb 2006

Purdue biologists visualize protein interaction that may initiate viral infection

Biologists at Purdue University have taken a "snapshot" of a Velcro-like protein on a cell's surface just after it attached to the dengue virus, a linkup thought to initiate the early stages of infection.

16 Feb 2006

Advancing knowledge of diet-gene interactions

Josi Ordovas, PhD, director of the Nutrition and Genomics Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University joined more than eighty other leading researchers in the fields of nutrition and genetics to co-author a report outlining their strategy for maximizing the impact of nutrigenomics research on global poverty and health.

16 Feb 2006

Researchers develop way to visualize synchronized interactions of nerve cells in the brain

Researchers at the University of Minnesota Medical School and the Brain Sciences Center at the Minneapolis VA Medical Center have discovered a new way to assess how brain networks act together.

16 Feb 2006

FOLFOX now treatment standard for colorectal cancer in the United States

One of the newest and most potent chemotherapies for colon cancer is as safe and effective for the elderly as it is for younger patients, based on a University of North Carolina at Chapel Hill-led data review.

16 Feb 2006

Hormone aldosterone linked to quality of hearing

Researchers have linked a hormone known to adjust levels of key brain chemicals to the quality of our hearing as we age. The more of the hormone that older people have in their bloodstream, the better their hearing is, and the less of the hormone, the worse their hearing is.

16 Feb 2006

Mystery of cot death may be explained

A failure to 'gasp' has long been proposed as the basis for sudden infant death syndrome, or cot death. A team at the University of Bristol has discovered a subset of cells in the brain that have the ability to self-generate nervous impulses, which appear essential for gasping. These cells have been termed 'pacemakers'.

16 Feb 2006

New children's heart valve

New valves and stents made of super-elastic, shape-memory metal alloy combined with less invasive procedure mean quicker recovery for children with heart disease.

16 Feb 2006

Diuretics improve exercise capacity in patients with congestive heart failure

Diuretics reduce the risk of death, delay heart deterioration and improve exercise capacity in patients with congestive heart failure, a new review of studies shows.

16 Feb 2006

Brain scans may detect neurological decline in normal people

Brain scans may detect neurological changes in people who exhibit no outward signs of cognitive decline but who later develop dementia or mental impairment, according to the results of a new study led by researchers at the University of California, Berkeley.

16 Feb 2006

Research may help explain Alzheimer's memory loss

Based on laboratory research, scientists at Georgetown University Medical Center have a new theory as to why people with Alzheimer's disease have trouble performing even the simplest memory tasks, such as remembering a family member's name.

16 Feb 2006

Anti-malarials most effective in lupus patients genetically at risk of high levels of TNF-alpha

Anti-malarial drugs are most effective in people with lupus who are genetically predisposed to high levels of tumour necrosis factor alpha and low levels of the cytokine IL-10.

16 Feb 2006

Central adiposity, regional fat distribution, and the risk of cholecystectomy in women

A bulging midriff almost doubles a woman's chances of developing gallstones and the need for surgery to remove them, finds an extensive study published ahead of print in Gut.

16 Feb 2006

Less is more hypothesis - gene loss may explain unique human traits

Humans and chimps share most of their genes, yet they differ dramatically in many ways - their walk, the sizes of their brains and their capacities for speech and language, for example.

16 Feb 2006

New way to culture adult stem cells from bone marrow

In a significant advance for regenerative medicine, researchers at Rice University have discovered a new way to culture adult stem cells from bone marrow such that the cells themselves produce a growth matrix that is rich in important biochemical growth factors.

16 Feb 2006

Causes of type 1 diabetes

Scientists are casting a wide, tightly woven net with the goal of catching the causes of type 1 diabetes.

16 Feb 2006

Discovery suggests potential treatment for regenerating nerve tissue after stroke

Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells.

16 Feb 2006

More pediatricians should counsel children and their parents about preventing skin cancer

More pediatricians should counsel children and their parents about preventing skin cancer, according to dermatology researchers from Wake Forest University Baptist Medical Center. A review of research literature confirmed that prevention should begin in childhood, yet found that the topic is discussed at less than 1 percent of well-child visits.

16 Feb 2006

Taking aim at one of mankind's most common diseases

A detailed structural picture of a molecule that plays a key role in activating the Epstein Barr Virus in human cells has now been obtained by researchers at the European Molecular Biology Laboratory (EMBL) and the Institute of Molecular and Structural Virology (IVMS), associated with the University Joseph Fourier and the CNRS, in Grenoble.

16 Feb 2006