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Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with an alternate therapy.

26 Jun 2018

Are wearable defibrillators a suitable alternative to surgically implanted devices?

Wearable defibrillators may be a safe and effective alternative to surgically implanted devices among children with ventricular arrythmias that increase the risk of sudden cardiac death, according to a new study.

26 Jun 2018

Patients receiving leadless pacemakers experience fewer complications, study finds

Patients receiving leadless pacemakers experience overall fewer short-term and mid-term complications than those receiving traditional transvenous pacemakers, a Cleveland Clinic-led research study found. The study was published today in the journal Heart Rhythm.

26 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Zucchini, brown rice, turkey soup - Medicaid plan offers food as medicine

Feliciano Pagan stood at his front door when the MANNA food truck pulled up to his two-story brick row home.

25 Jun 2018

UC San Diego launches new bacteriophage therapy center

With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in collaboration with national research institutions and private industry, are leveraging hard-won expertise to exploit a natural viral enemy of pathogenic bacteria, creating North America's first Center for Innovative Phage Applications and Therapeutics

22 Jun 2018

The GW Cancer Center expands bone marrow transplant and cell therapies

The George Washington University (GW) Cancer Center is pleased to welcome a team of internationally-recognized experts who together will lead the expanded Bone Marrow Transplant and Cell Therapies Program.

22 Jun 2018

Scientists discover the molecular trigger of necroptosis

Researchers have uncovered a trigger for an immune-related cell death pathway called necroptosis. The discovery could be used to develop new treatments for cancer and immune disorders.

21 Jun 2018

Study finds cell-free DNA profiling as versatile method to monitor UTIs

Using shotgun DNA sequencing, Cornell University researchers have demonstrated a new method for monitoring urinary tract infections that surpasses traditional methods in providing valuable information about the dynamics of the infection as well as the patient's biological response.

21 Jun 2018

Kidney donation among carefully-selected older adults poses minimal risks

With increasing organ demand, living kidney donation from older donors has become more common. A new Clinical Transplantation study indicates that kidney donation among carefully-selected adults over 60 years of age poses minimal perioperative risks and no added risk of long-term kidney failure.

20 Jun 2018

Scientists develop novel computational framework to support personalized cancer treatment

Researchers at Columbia University Irving Medical Center have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug combinations that are most likely to kill them.

19 Jun 2018

BIDMC scientists develop new tool to benefit patients with HCV-associated liver failure

An estimated 3.5 million people in the United States have chronic hepatitis C (HCV), according to the Centers for Disease Control and Prevention.

18 Jun 2018

Cleveland Clinic receives $3.7 million grant from AHA for atrial fibrillation research

The American Heart Association has awarded Cleveland Clinic a $3.7 million grant for atrial fibrillation research. The four-year, competitive award will support three synergistic projects aimed at improving outcomes for patients with atrial fibrillation, a common heart rhythm abnormality.

13 Jun 2018

Hematopoietic stem cell transplant improves survival for multiple myeloma patients

Researchers at UC Davis have confirmed that autologous hematopoietic stem cell transplant improves survival for people suffering from multiple myeloma, yet many potentially eligible patients never undergo the procedure.

13 Jun 2018

Penn research team identifies novel therapeutic target for heart disease

Changes in cellular struts called microtubules (MT) can affect the stiffness of diseased human heart muscle cells, and reversing these modifications can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure, found researchers from the Perelman School of Medicine at the University of Pennsylvania.

12 Jun 2018

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today new positive results from its Phase 1/2 study with lumasiran, an investigational RNAi therapeutic targeting glycolate oxidase for the treatment of Primary Hyperoxaluria Type 1.

8 Jun 2018

Practicing with fake organs helps surgeon to perform complex cancer surgery

Anthony Camnetar remembers the first time he was told that he had von Hippel-Lindau syndrome, a rare genetic disorder.

7 Jun 2018

Researchers transplant lab-grown neural cells in mice with spinal injuries to improve breathing

Researchers from Drexel University College of Medicine and the University of Texas at Austin improved respiratory function in rodents with spinal cord injuries after successfully transplanting a special class of neural cells, called V2a interneurons.

7 Jun 2018

Faeces donors do it out of willingness not money - study

Healthy adults who have a good constitution and have a healthy heart are being called forth to donate samples of their faeces to science. The donors would be screened rigorously before they can be included and would be compensated modestly for their donations say researchers.

6 Jun 2018

New study examines living kidney donors' concerns on kidney removal

In a new study that examined living kidney donors' concerns about their decision to undergo kidney removal, long-term kidney health, aspects of surgery and recovery, and impacts on life satisfaction were among those that donors felt were most important.

1 Jun 2018

Transplant News and Research

Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

Are wearable defibrillators a suitable alternative to surgically implanted devices?

Patients receiving leadless pacemakers experience fewer complications, study finds

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Zucchini, brown rice, turkey soup - Medicaid plan offers food as medicine

UC San Diego launches new bacteriophage therapy center

The GW Cancer Center expands bone marrow transplant and cell therapies

Scientists discover the molecular trigger of necroptosis

Study finds cell-free DNA profiling as versatile method to monitor UTIs

Kidney donation among carefully-selected older adults poses minimal risks

Scientists develop novel computational framework to support personalized cancer treatment

BIDMC scientists develop new tool to benefit patients with HCV-associated liver failure

Cleveland Clinic receives $3.7 million grant from AHA for atrial fibrillation research

Hematopoietic stem cell transplant improves survival for multiple myeloma patients

Penn research team identifies novel therapeutic target for heart disease

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Practicing with fake organs helps surgeon to perform complex cancer surgery

Researchers transplant lab-grown neural cells in mice with spinal injuries to improve breathing

Faeces donors do it out of willingness not money - study

New study examines living kidney donors' concerns on kidney removal

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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