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Analysis of Fcg Receptor haplotypes in rheumatoid arthritis

People with a specific combination of variants of two genes, encoding two different receptors for the antibody Fc gamma, are three times more likely to develop rheumatoid arthritis than individuals with different variant combinations.

28 Nov 2005

Epidural versus non-epidural or no analgesia in labour

Women who receive epidurals during labor report less pain than those who choose opiates or natural childbirth, according to a systematic review of evidence.

28 Nov 2005

Megestrol acetate may combat weight loss during radiation treatments

A new study by researchers at Wake Forest University Baptist Medical Center and colleagues shows that a drug originally used to treat breast cancer may help combat the severe weight loss that can plague patients undergoing radiation treatment for lung and head and neck cancer.

28 Nov 2005

Potential new treatment for pancreatic cancer

Johns Hopkins Kimmel Cancer Center researchers are encouraged by early results of a treatment vaccine for pancreatic cancer, a disease with few options and low odds for long-term survival.

28 Nov 2005

Loss of genes on chromosome 1 or 11 raises the risk of death from the children's cancer neuroblastoma

A new study reports that a loss of genes on chromosome 1 or chromosome 11 raises the risk of death from the children's cancer neuroblastoma, even when other indicators seem to point to a lower-risk form of the disease.

28 Nov 2005

Dining out may increase cardiovascular disease risk in children

Children who frequently eat out score worse on measures of cardiovascular disease (CVD) risk than those who eat more meals at home, researchers reported at the American Heart Association's Scientific Sessions 2005.

28 Nov 2005

Study finds AKT blocks cancer cell motility

PIn investigating the molecular mechanisms of cancer cell motility - the unique property that enables cancer to spread from its primary origin to other parts of the body - researchers have uncovered a surprising role for the AKT/PKB (protein kinase B) enzyme

26 Nov 2005

Methylphenidate may be effective in treating autism

Methylphenidate, a medication used to treat attention-deficit hyperactivity disorder (ADHD), may be effective in treating hyperactivity symptoms in children with autism and related pervasive developmental disorders, researchers report in the November Archives of General Psychiatry.

26 Nov 2005

Risk of cervical and other cancers after treatment of cervical intraepithelial neoplasia

Women who have had pre-cancerous cells removed remain at higher than average risk of developing cervical cancer in the 20 years following treatment, says research in the British Medical Journal (BMJ).

26 Nov 2005

Researchers gain detailed view yet of the heart of the translocon

Researchers have gained the most detailed view yet of the heart of the translocon, a channel through which newly constructed proteins are inserted into the cell membrane. The process of transporting proteins across or into membranes is a critical function that occurs in every cell.

26 Nov 2005

Potential drug target for malaria

Researchers have identified an enzyme crucial to the malaria parasite's invasion of red blood cells, according to a study in the open-access journal, PLoS Pathogens.

26 Nov 2005

Two novel drugs kill breast cancer tumor cells

Two new drugs, when combined, killed up to 75 percent of breast cancer tumor cells in mice and suppressed the regrowth of tumors, according to researchers at the Virginia Commonwealth University Massey Cancer Center.

26 Nov 2005

Study finds common pollutants linked to fetal growth retardation

Babies born to women exposed to high ozone levels during pregnancy are at heightened risk for being significantly underweight, according to researchers at the Keck School of Medicine of the University of Southern California.

26 Nov 2005

Genetic influences behind Dupuytren's disease or contracture

A crippling condition that can result in sufferers losing their fingers is to be investigated by scientists in one of the most detailed studies into the genetic causes of the disease ever carried out.

From The University of Manchester 26 Nov 2005

New door opens for anti-aging research in humans

A counterintuitive experiment has resulted in one of the longest recorded life-span extensions in any organism and opened a new door for anti-aging research in humans.

26 Nov 2005

New European Union directive on food labelling

Safety for people with food allergies will be boosted later this month when new European laws will force manufacturers to label their food more accurately, but the laws do not offer full protection, says an editorial in the British Medical Journal (BMJ).

26 Nov 2005