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Gene silencing and microRNA discovery

One of the body's primary strategies for regulating its genome is a kind of targeted gene silencing orchestrated by small molecules called microRNAs, or miRNAs.

7 Nov 2005

Tryptophan metabolites play an important role in the immune system

Tryptophan is the source of Thanksgiving legend and grist for a "Seinfeld" episode, but it's not the chemical that you'd expect to find in Lawrence Steinman's lab.

7 Nov 2005

Smokeless tobacco products are not necessarily a safe alternative to smoking

According to the U.S. Centers for Disease Control and Prevention, nearly one-fourth of Americans are smokers. That's more than 60 million people who are at increased for lung cancer, the leading cause of cancer-related deaths nationwide.

3 Nov 2005

Young hockey player injuries studied - suprising findings

Unintentional collisions and falling into the boards cause more injuries in young hockey players than the practice of body checking, researchers at the University at Buffalo have found.

3 Nov 2005

Expert highlights public health problem posed by colorectal cancer

Colorectal cancer is a significant public health problem for which differing treatment regimes hold different benefits in associated efficacy, safety and tolerability, according to study findings showcased at the 13th European Cancer Conference (ECCO).

3 Nov 2005

Exercise is good for multiple sclerosis, but it must be done correctly

Aerobic exercise is thought to help persons with multiple sclerosis fight fatigue, the most common symptom of the disease. Yet MS also appears to cause the body to heat up more quickly, compromising the ability to exercise.

3 Nov 2005

MRI measurements of scar tissue accurately predict the risk of arrhythmia-related sudden death

Using magnetic resonance imaging (MRI) scans of the heart wall, researchers at Johns Hopkins have found that people whose muscle wall thickness contained more than 25 percent scar tissue were approximately nine times more likely to test positive for a fast and dangerous heart rhythm known as ventricular arrhythmia.

3 Nov 2005

Ospemifine may also help to prevent breast cancer

A tamoxifen-like drug developed by UC Davis and Finnish researchers, now in clinical testing as a treatment for vaginal atrophy, may also help to prevent breast cancer, two preliminary studies suggest.

3 Nov 2005

Teenages who eat regularly with their family less likely to be overweight

They might prefer to be in front of the TV or Playstation, but Brisbane teenagers are likely to be healthier if they eat meals with mum and dad.

3 Nov 2005

Vaccine that targets nicotine rather than the brain's reaction to it

Since smoking became popular in America in the 1930s, lung cancer rates have continued to climb. Today, it is still the leading cause of cancer-related deaths, with totals more than the other five leading cancers combined.

3 Nov 2005

Stem cells appear to play a role in repairing organs

Not least because undifferentiated cells with features typical of stem cells are being increasingly found in organs like the liver, brain, and muscles, scientists are beginning to assume that these cells play a role in repairing organs.

3 Nov 2005

Socioeconomic status determines life expectancy in HIV patients

HIV patients with a low socioeconomic status are likelier to die much more often than patients with higher levels of wealth and education, a new UCLA study has found.

3 Nov 2005

Neurological and neuromuscular diseases raise risk of complications from flu

As another flu season approaches, patients with neurological and neuromuscular disease are especially vulnerable to respiratory failure caused by influenza.

3 Nov 2005

Neuron finding could advance understanding of epilepsy and age-related memory loss

Neurons experience large-scale changes across their dendrites during learning, say neuroscientists at The University of Texas at Austin in a new study that highlights the important role that these cell regions may play in the processes of learning and memory.

3 Nov 2005

Substance found in evening primrose oil inhibits breast cancer gene

Gamma-linolenic acid (GLA), a substance in evening primrose oil and several other plant oils used in herbal medicine, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers, Northwestern University researchers report.

3 Nov 2005

Fundamental insight about protein evolution

While searching for new targets for malaria drugs and vaccines, a team including a Howard Hughes Medical Institute (HHMI) medical student fellow reached a fundamental insight about evolution: different species make use of similar sets of proteins in different ways.

3 Nov 2005

New method to find deadly malaria parasite

Researchers at UCSD have discovered that the single-cell parasite responsible for an estimated 1 million deaths per year worldwide from malaria has protein "wiring" that differs markedly from the cellular circuitry of other higher organisms

3 Nov 2005

DN-101 may protect against major side effects of chemotherapy

Men with advanced prostate cancer who take an experimental, high-dose vitamin D pill with chemotherapy live about eight months longer than those receiving chemotherapy and placebo, according to a new study.

3 Nov 2005

Calcitriol - promising chemopreventive agent that may prevent prostate cancer

The active metabolite of vitamin D, calcitriol, and other vitamin D analogs are promising chemopreventive agents that may prevent prostate cancer, according to a study presented today at the American Association for Cancer Research's 4th annual Frontiers in Cancer Prevention Research meeting in Baltimore.

3 Nov 2005

Simple, at-home treatment for jet lag

A simple, at-home treatment -- a single light box and the over-the-counter drug melatonin -- allows travelers to avoid jet lag by resetting their circadian body clock before crossing several time zones, according to new research being published in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

3 Nov 2005