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Scientists find key step in a signaling pathway that helps orchestrate embryonic development

The study, reported in Nature (Oct. 13, 2005), focuses on the Hedgehog family of signaling molecules, which play a central role in directing development of the early embryo's growth and spatial plan, as well as its later organ and limb development. Defects in Hedgehog signaling are a significant cause of some birth defects and cancers.

25 Oct 2005

Study provides insight into cellular defenses against genetic mutation

With their latest discovery, researchers have significantly advanced the understanding of how human cells protect themselves from constant and potentially destructive changes in gene expression.

25 Oct 2005

Australian researchers determine structure of JAK2 kinase, huge implications for development of new cancer drugs

Researchers from Monash's Department of Biochemistry and Molecular Biology have determined the structure of the protein JAK2 kinase, a discovery with huge implications for the design and development of new cancer drugs.

25 Oct 2005

Common anthrax sampling methods need improvement

A research team from the National Nuclear Security Administration's Sandia National Laboratories has discovered that common anthrax sampling methods need improvement. The research shows that more deadly spores remain after decontamination than previously believed.

25 Oct 2005

Most communities woefully unprepared for outbreaks of killer flu

If health officials and media prognosticators are accurate, this coming winter may bring with it one of the most sweeping, deadly outbreaks of killer flu that the world has ever seen.

25 Oct 2005

Gold nanorods injected into the bloodstream may be used to develop an advanced medical imaging tool

Researchers at Purdue University have taken a step toward developing a new type of ultra-sensitive medical imaging technique that works by shining a laser through the skin to detect tiny gold nanorods injected into the bloodstream.

25 Oct 2005

Two competing drug-eluting stents work equally well

After completing the most comprehensive U.S.-based study of its kind, Dr. Charles Simonton reported that the performance of two competing coronary stents was "virtually identical" in head-to-head comparisons.

25 Oct 2005

Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis

"Recurrent wheeze and breathlessness are common in people with cystic fibrosis, and bronchodilators are commonly prescribed," according to lead author Clare Halfhide, M.D., of the Royal Liverpool Children's Hospital in England. "Despite their wide-scale and often long-term use, there is limited objective evidence about their efficacy in cystic fibrosis."

25 Oct 2005

New strategies to help developing countries address neglected diseases

For the health challenges facing developing countries, the numbers alone are staggering. Every day, 40,000 people - enough to fill a sports stadium - die from preventable infectious diseases and malnutrition. Entire generations of human potential are perishing.

25 Oct 2005

Women's sexual function improves when partners are administered Vardenafil for erectile dysfunction

Couples share wine, movies, vacations and bedrooms. Do couples also share sexual problems and solutions?

25 Oct 2005

Gene therapy used to successfully treat heart failure

University of Pittsburgh investigators have for the first time used gene therapy to successfully treat heart failure and other degenerative muscle problems in an animal model that is genetically susceptible to a human muscular dystrophy.

25 Oct 2005

Number of color-sensitive cones in the human retina differs dramatically among people

First-ever images of living human retinas have yielded a surprise about how we perceive our world.

25 Oct 2005

Can strength-training exercises reduce or prevent lymphedema symptoms in breast cancer?

In a novel research study to begin this week at the Abramson Cancer Center of the University of Pennsylvania, Kathryn Schmitz, PhD, MPH, Assistant Professor in Epidemiology, will help to determine the extent to which a slowly progressive program of strength-training exercises is safe for breast cancer survivors with and without symptoms of lymphedema.

25 Oct 2005

Antisense molecules may hold promise in treating brain chemical problems such as Alzheimer's

Saint Louis University research shows a new class of drugs may hold promise in treating brain chemical problems such as Alzheimer's disease, says the principal investigator of research published in an early on-line version of Peptides.

25 Oct 2005

Comprehensive home-based environmental intervention results in decreased asthma symptoms

Through efforts to limit exposure to environmental irritants, health workers and municipalities can cut illness generally among inner-city children with asthma and also the number of clinic visits for those young patients by at least 19 percent, a new study concludes. The cost can be as low as $1,469 per affected family.

25 Oct 2005

Research News and Research

Scientists find key step in a signaling pathway that helps orchestrate embryonic development

Study provides insight into cellular defenses against genetic mutation

Australian researchers determine structure of JAK2 kinase, huge implications for development of new cancer drugs

Common anthrax sampling methods need improvement

Most communities woefully unprepared for outbreaks of killer flu

Gold nanorods injected into the bloodstream may be used to develop an advanced medical imaging tool

Two competing drug-eluting stents work equally well

Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis

New strategies to help developing countries address neglected diseases

Women's sexual function improves when partners are administered Vardenafil for erectile dysfunction

Gene therapy used to successfully treat heart failure

Number of color-sensitive cones in the human retina differs dramatically among people

Can strength-training exercises reduce or prevent lymphedema symptoms in breast cancer?

Antisense molecules may hold promise in treating brain chemical problems such as Alzheimer's

Comprehensive home-based environmental intervention results in decreased asthma symptoms

As men grow older, bladder function can worsen and the prostate gland may be responsible

Single blast of ultrasound destroys cancer cells

Wellcome Trust awards £8.1 million to tackle tropical diseases

Viagra significantly reduces stress on the heart

Despite warning dangerous ADHD drug still being sold

Spectroscopy Applications in the Environment eBook eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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