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Access to genetic counseling and testing are an important part of cancer control

Ten years after the identification of the first breast cancer susceptibility genes so few high-risk minority women have received genetic counseling or testing that the standard methods of calculating risk have not been validated in these groups and the results of genetic testing can still produce surprises.

18 Oct 2005

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

The humble yeast has revealed the molecular workings of an anti-cancer drug that stops the growth and spread of tumours in humans by starving their blood supply.

18 Oct 2005

Health insurers are turning to a new approach to get doctors and hospitals to do better

In this approach, insurers offer financial rewards for better or more efficient care and sometimes create penalties for poor performance. Even though it has become commonplace, there is little evidence about its impact on care, says R. Adams Dudley, MD, MBA, a professor in the UCSF Institute for Health Policy Studies and the Department of Medicine.

18 Oct 2005

HIV drug combo Trimethoprim-sulfamethoxazole highly effective at preventing malaria

A drug combination used to prevent pneumonia and opportunistic bacterial infection in persons with HIV/AIDS has unexpectedly been found to be highly effective at preventing malaria, according to a study published in the November 15 issue of The Journal of Infectious Diseases, now available online.

18 Oct 2005

Controlling antibiotic-prescribing practices in hospitals

Plenty of promising strategies exist to control antibiotic-prescribing practices, but no single method emerges as the best for hospital patients, according to a new review of studies.

18 Oct 2005

Treating malignant melanoma of the uvea with radiation therapy can spare patients from significant vision loss

Treating a rare form of eye cancer with radiation therapy can spare patients from significant vision loss, according to new research at Wake Forest University Baptist Medical Center.

18 Oct 2005

Evidence is mounting to link toxoplasmosis with schizophrenia

Keep pet cats inside, stop feeding strays, cook meat sufficiently and reconsider the way the veterinary profession and public health agencies think - and teach - about the zoonotic pathogen Toxoplasma gondii.

18 Oct 2005

Steroids and the chicken pox are a bad combination for children

Children who have been treated with steroids and are exposed to chicken pox tend to have a more severe case of the virus, according to pediatric oncologists at Brenner Children's Hospital, part of Wake Forest University Baptist Medical Center.

18 Oct 2005

Radical prostatectomy may be a safe option for the treatment of prostate cancer

Prostate cancer is the most common non-skin cancer in American men and the third most common cause of cancer death. In patients with localized disease, radical prostatectomy is associated with lower disease-specific mortality, lower rates of local progression and metastases, and higher overall survival compared with conservative management.

18 Oct 2005

Single men are less likely to seek radiation re-treatment for pain caused by prostate cancer

"Patients often experience a great deal of pain if their cancer spreads to the bone," explained Andre Konski, M.D., M.B.A., M.A., F.A.C.R., director of clinical research in the radiation oncology department at Fox Chase Cancer Center and lead author of the paper on the Radiation Therapy Oncology Group study (RTOG 97-14).

18 Oct 2005

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Reporting in two companion papers in the October 19 issue of the Journal of Neuroscience, investigators from the Gladstone Institute of Neurological Disease show in genetically engineered mouse models of the disease that the accumulation of Alzheimer-related neurotoxic amyloid-beta (Aâ) peptides can deplete key proteins in a specific memory center of the brain.

18 Oct 2005

Newly discovered role of MECP2 gene in Rett Syndrome

Huda Zoghbi, of Baylor College of Medicine and the Howard Hughes Medical Institute and Juan Young, also of Baylor and colleagues report in the online Early Edition of the Proceedings of the National Academy of Science, posted the week of October 17, 2005, that the Rett Syndrome gene, MECP2, regulates RNA splicing.

18 Oct 2005

Study demonstrates feasibility of a revolutionary, minimally invasive approach to introducing an electrical lead to stimulate the heart

Correcting the timing of heart contractions through cardiac resynchronization therapy can be a lifesaver for people with advanced heart failure. But the procedure, as it is done today, fails in about 15 percent of patients.

18 Oct 2005

Cutting-edge research to develop this range of next-generation biomedical devices

Revolutionary new self-diagnostic devices to provide early warning of deadly and debilitating illnesses like cancer, diabetes and heart disease are the aim of a Euro 22.5m Science Foundation Ireland research facility to be established at Dublin City University.

18 Oct 2005

Epidurals in labour and delivery reduce pain but can increase the risk of needing forceps

Epidurals in labour and delivery reduce pain but can increase the risk of needing forceps Pain relief is an important issue for women in labour and epidurals are increasingly used.

18 Oct 2005

Not enough evidence to recommend routine bed rest for hypertension in pregnancy

Currently there is a lack of evidence that keeping pregnant women with high blood pressure in bed for a prolonged period of time improves the chance of a healthy delivery. Prolonged bed rest is disruptive to women's lives, carries the risk of generating blood clots, and may be expensive.

18 Oct 2005

No credible evidence behind claims of harm from the MMR vaccination

There was no credible evidence behind claims of harm from the MMR vaccination. This is the conclusion drawn by the Cochrane Review Authors, an international team of researchers, after carefully drawing together all of the evidence found in 31 high quality studies from around the world.

18 Oct 2005

Discovery increases the yield of stem cells from umbilical cord blood

A team of bioengineers led by the University of Toronto has discovered a way to increase the yield of stem cells from umbilical cord blood, to an extent which could broaden therapeutic use of these cells.

18 Oct 2005

No evidence of a "safe" threshold with environmental toxins

Four of the most widespread environmental toxins - lead, trihalomethanes (found in drinking water), ionizing radiation from indoor radon gas, and tobacco smoke - can cause serious damage to health even at very low levels, say researchers in the open access journal PLoS Medicine.

18 Oct 2005

Protein involved in 'mad cow' disease

The journal Brain Research has recently published the results of research work by scientists from the University of Navarra.

18 Oct 2005

Research News and Research

Access to genetic counseling and testing are an important part of cancer control

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

Health insurers are turning to a new approach to get doctors and hospitals to do better

HIV drug combo Trimethoprim-sulfamethoxazole highly effective at preventing malaria

Controlling antibiotic-prescribing practices in hospitals

Treating malignant melanoma of the uvea with radiation therapy can spare patients from significant vision loss

Evidence is mounting to link toxoplasmosis with schizophrenia

Steroids and the chicken pox are a bad combination for children

Radical prostatectomy may be a safe option for the treatment of prostate cancer

Single men are less likely to seek radiation re-treatment for pain caused by prostate cancer

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Newly discovered role of MECP2 gene in Rett Syndrome

Study demonstrates feasibility of a revolutionary, minimally invasive approach to introducing an electrical lead to stimulate the heart

Cutting-edge research to develop this range of next-generation biomedical devices

Epidurals in labour and delivery reduce pain but can increase the risk of needing forceps

Not enough evidence to recommend routine bed rest for hypertension in pregnancy

No credible evidence behind claims of harm from the MMR vaccination

Discovery increases the yield of stem cells from umbilical cord blood

No evidence of a "safe" threshold with environmental toxins

Protein involved in 'mad cow' disease

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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