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Next generation of effective viral-based therapies for cancer

Researchers at Columbia University Medical Center continue to make strides in their work to develop the next generation of effective viral-based therapies for cancer.

21 Sep 2005

First clinical guidelines to help improve the diagnosis and treatment of people with normal pressure hydrocephalus

An international team of medical experts led by a Virginia Commonwealth University researcher has established the first clinical guidelines to help improve the diagnosis and treatment of people with normal pressure hydrocephalus, a debilitating condition in the brain that often goes undiagnosed or is misdiagnosed as Alzheimer's or Parkinson's disease.

21 Sep 2005

Effects of 10 commonly prescribed second-generation antidepressants studied

Because clinical depression is so disabling and affects more than 16 percent of adults in the United States at some time in their lives, researchers have worked hard to develop more effective treatments. But how much better are the newer pharmaceuticals?

21 Sep 2005

Eating lots of fruits and vegetables greatly reduces risk of developing pancreatic cancer

In one of the largest studies of its kind, University of California - San Francisco (UCSF) researchers have found that eating lots of fruits and vegetables - particularly vegetables - is associated with about a 50 percent reduction in the risk of developing pancreatic cancer. Pancreatic cancer is difficult to diagnose and remains largely untreatable.

21 Sep 2005

Scintigraphy scan may help clinicians properly diagnose and then treat two forms of cardiac amyloidosis

"Clinically, this finding helps differential diagnosis and reduces the risk of misdiagnosis between two conditions with very different therapeutic options," said Claudio Rapezzi, M.D. from the University of Bologna and S. Orsola-Malpighi Hospital in Bologna, Italy.

21 Sep 2005

Simple organism can produce 10 trillion varieties of a single protein

A team led by University of California, San Diego biochemists has discovered the mechanism by which a simple organism can produce 10 trillion varieties of a single protein, a finding that provides a new tool to develop novel drugs.

21 Sep 2005

Antibiotic resistance has put humans in an escalating 'arms race' with infectious bacteria

...as scientists try to develop new antibiotics faster than the bacteria can evolve new resistance strategies. But now, researchers have a new strategy that may give them a leg up in the race -- reproducing in the lab the natural evolution of the bacterial enzymes that confer resistance.

21 Sep 2005

Genetically engineered animals help in scientific research that may benefit children

The recent use of genetically modified mice and rats in combination with an animal model of obstructive nephropathy, a type of renal disease, has given researchers new insight in the development of kidney disease.

21 Sep 2005

Digital mammography detects more cancers than screen film mammography

A landmark breast cancer screening trial shows that digital mammography detected more cancers - up to 28 percent more - than screen film mammography in women 50 and younger, premenopausal and perimenopausal women, and women with dense breasts.

21 Sep 2005

Increased ovarian cancer risk not linked to cancer family history

Women with a strong family history of breast cancer but who don't have breast cancer genetic mutations can now be reassured that they are not at increased risk for ovarian cancer, according to a new study by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).

21 Sep 2005

Key neural system at risk from prenatal exposure to alcohol

In a study of adult monkeys who were exposed to moderate amounts of alcohol in utero, scientists have found that prenatal exposure to alcohol - even in small doses - has pronounced effects on the development and function later in life of the brain's dopamine system, a critical component of the central nervous system that regulates many regions of the brain.

21 Sep 2005

First true animal model for psoriasis

Scientists at the Research Institute of Molecular Pathology in Vienna have developed the first true animal model for psoriasis and have been able to address the initial steps and possible causes of the disease.

20 Sep 2005

New evidence for a genetic pathway that is involved in the recurrence of breast cancer

A study published in the September issue of Cancer Cell provides new evidence for a genetic pathway that is involved in the recurrence of breast cancer and identifies a potential target for development of new anticancer therapeutics.

20 Sep 2005

Gene mutation may increase the risk of prostate cancer up to three times in African-American

Researchers have identified a gene mutation that may increase the risk of prostate cancer up to three times in African-American men with a family history of the disease.

20 Sep 2005

Students might actually overestimate rather than underestimate their levels of drinking

Numerous studies have shown that misuse of alcohol by college students in the U.S. is a pervasive problem. Most of what is known about consumption levels is based on self-report survey data, which assumes that students are aware of and can accurately calculate how much alcohol they consume.

20 Sep 2005

Heavy alcohol consumption can significantly increase men's risk of developing atrial fibrillation

A large-scale study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that heavy alcohol consumption - 35 or more drinks per week -- can significantly increase men's risk of developing atrial fibrillation, a dangerous type of arrhythmia and one of the leading risk factors for stroke.

20 Sep 2005

Dual association of beta-carotene with risk of tobacco-related cancers

A new study of French women has found that high beta-carotene intake--through a combination of diet or supplementation--is associated with a higher risk of tobacco-related cancers in smokers, but the risk of these cancers decreases with increasing beta-carotene intake in nonsmokers.

20 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the September 21 issue of the Journal of the National Cancer Institute.

20 Sep 2005

Significant death risk linked to airborne particles

Experts may be significantly underestimating air pollution's role in causing early death, according to a team of American and Canadian researchers, who studied two decades' worth of data on residents of the Los Angeles metro area.

20 Sep 2005

Family-centered approach improves communication and care in intensive care unit

A nationwide hospital program developed to support families visiting loved ones in the intensive care unit (ICU) has significant benefits for families, patients, and team members in the ICU, shows a new study.

20 Sep 2005

Research News and Research

Next generation of effective viral-based therapies for cancer

First clinical guidelines to help improve the diagnosis and treatment of people with normal pressure hydrocephalus

Effects of 10 commonly prescribed second-generation antidepressants studied

Eating lots of fruits and vegetables greatly reduces risk of developing pancreatic cancer

Scintigraphy scan may help clinicians properly diagnose and then treat two forms of cardiac amyloidosis

Simple organism can produce 10 trillion varieties of a single protein

Antibiotic resistance has put humans in an escalating 'arms race' with infectious bacteria

Genetically engineered animals help in scientific research that may benefit children

Digital mammography detects more cancers than screen film mammography

Increased ovarian cancer risk not linked to cancer family history

Key neural system at risk from prenatal exposure to alcohol

First true animal model for psoriasis

New evidence for a genetic pathway that is involved in the recurrence of breast cancer

Gene mutation may increase the risk of prostate cancer up to three times in African-American

Students might actually overestimate rather than underestimate their levels of drinking

Heavy alcohol consumption can significantly increase men's risk of developing atrial fibrillation

Dual association of beta-carotene with risk of tobacco-related cancers

Change in gene may be underlying molecular defect in some colorectal cancers

Significant death risk linked to airborne particles

Family-centered approach improves communication and care in intensive care unit

A new way of characterising biomolecules eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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