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Manic depression linked to two chromosomal regions in the human genome

An international team of 53 researchers has offered the most convincing evidence so far linking bipolar disorder, also known as manic depression, to two chromosomal regions in the human genome. The finding gives scientists refined targets for further gene studies.

19 Sep 2005

Impact of prevention strategies and improvements in stroke healthcare

Coinciding with National Stroke Week in Australia (19 - 25 September 2005) is the release of results from two recent stroke studies from the George Institute for International Health that investigate both the causative factors as well as a little studied outcome of stroke, that of depression.

19 Sep 2005

MRC study to monitor Pentosan Polysulphate as a treatment for Creutzfeldt-Jakob disease receives approval

The plans for a monitoring study on patients being treated with Pentosan Polysulphate (PPS) for CJD and variant CJD have received a favourable opinion from the Eastern Multi-Centre Research Ethics Committee. This follows a provisional opinion from the committee in August.

19 Sep 2005

Bariatric surgery is a safe option for treating obese patients who have coronary artery disease

The findings are important because coronary artery disease patients can see a significant benefit with a successful procedure. The resulting weight loss is also followed by an improvement in blood pressure, cholesterol, blood sugar and sleep apnea, all factors linked to coronary artery disease.

12 Sep 2005

New and unusual class of genes plays an important role in the development of chronic lymphocytic leukemia

The study found that the loss of two genes for producing small molecules known as microRNAs enables damaged cells to survive, rather than normally self-destructing before they become cancerous.

12 Sep 2005

Women who suffer heart attacks wait longer to be assessed

Women who suffer heart attacks wait longer to be assessed, admitted and receive treatment than men with the same condition, according to a paper in the latest Journal of Advanced Nursing.

12 Sep 2005

Concerns over the privacy of patients could be hampering efforts to spot disease clusters

...and monitor the health effects of environmental pollution, according to researchers in the latest edition of the Journal of Biomedical Informatics.

12 Sep 2005

Vical and NIH to evaluate enhanced-delivery HIV vaccine

Vical Incorporated today announced plans to develop and evaluate electroporation-enhanced delivery of therapeutic and preventive DNA vaccines against HIV

12 Sep 2005

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

A major finding by researchers at the La Jolla Institute for Allergy & Immunology (LIAI) has identified a previously unknown cellular mechanism that acts as an off switch for immune system function.

12 Sep 2005

RNAi therapeutic successful for treatment of SARS respiratory virus in Rhesus Macaque

Intradigm Corporation announced today its collaboration with Chinese academic and biotech groups has achieved clear evidence of prophylactic and therapeutic effects of siRNA (small interfering RNA) agents in Rhesus monkey to treat SARS coronavirus (SCV) respiratory infection.

12 Sep 2005

Screening test for cells that activate immune system

UT Southwestern Medical Center researchers are the first to create a large-scale, cell-based screening method that identifies which compounds activate immune-response cells that hold promise for future cancer-fighting vaccines.

12 Sep 2005

Need for more outdoor play spaces so that children could have more choice over materials, locations and playmates

Young children may be missing out on 'pretend' games like pirates and spacemen due to the demands of the school curriculum, according to research funded by the Economic and Social Research Council (ESRC).

12 Sep 2005

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

A new treatment for patients with a type of bile duct cancer promises a greater chance at survival by combining radiation, chemotherapy and liver transplantation, Mayo Clinic physicians report in the September issue of the Annals of Surgery.

12 Sep 2005

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

The tissue-specific elongation factor eEF1A2 might be an oncoprotein involved in breast cancer.

12 Sep 2005

Nuclear receptor proteins could change anti-inflammatory treatments

Several nuclear receptor proteins appear to overlap in their ability to exert anti-inflammatory effects, according to new research by scientists at the University of California, San Diego (UCSD).

12 Sep 2005

Large scale study to see if angioplasty can be safely performed in small hospitals

Cardiologists at Johns Hopkins have launched a nationwide study of more than 16,000 patients to see if a potentially life-saving procedure called angioplasty can be safely performed in smaller, community hospitals, easing access to the therapy for patients. Researchers expect to enroll the first study patients in early fall 2005.

12 Sep 2005

Amantadine resistant avian influenza viruses more common in Southeast Asia than North America

Resistance to the antiviral drug amantadine is spreading more rapidly among avian influenza viruses of H5N1 subtype in Southeast Asia than in North America, according to the study done by investigators at St. Jude Children's Research Hospital.

12 Sep 2005

Clioquinol appears to block the genetic action of Huntington's disease

Clioquinol, an antibiotic that was banned for internal use in the United States in 1971 but is still used in topical applications, appears to block the genetic action of Huntington's disease in mice and in cell culture, according to a study reported by San Francisco VA Medical Center (SFVAMC) researchers.

12 Sep 2005

Genetic basis for susceptibility to alcohol abuse confirmed

A new set of experiments in mice confirms that a brain receptor associated with the reinforcing effects of marijuana also helps to stimulate the rewarding and pleasurable effects of alcohol.

12 Sep 2005

A breakthrough in R&D for neglected diseases

A dramatic sea-change in research into ten so-called "neglected diseases," such as malaria, leprosy and sleeping sickness, could result in at least eight new drugs being developed by 2010.

12 Sep 2005

Research News and Research

Manic depression linked to two chromosomal regions in the human genome

Impact of prevention strategies and improvements in stroke healthcare

MRC study to monitor Pentosan Polysulphate as a treatment for Creutzfeldt-Jakob disease receives approval

Bariatric surgery is a safe option for treating obese patients who have coronary artery disease

New and unusual class of genes plays an important role in the development of chronic lymphocytic leukemia

Women who suffer heart attacks wait longer to be assessed

Concerns over the privacy of patients could be hampering efforts to spot disease clusters

Vical and NIH to evaluate enhanced-delivery HIV vaccine

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

RNAi therapeutic successful for treatment of SARS respiratory virus in Rhesus Macaque

Screening test for cells that activate immune system

Need for more outdoor play spaces so that children could have more choice over materials, locations and playmates

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

Nuclear receptor proteins could change anti-inflammatory treatments

Large scale study to see if angioplasty can be safely performed in small hospitals

Amantadine resistant avian influenza viruses more common in Southeast Asia than North America

Clioquinol appears to block the genetic action of Huntington's disease

Genetic basis for susceptibility to alcohol abuse confirmed

A breakthrough in R&D for neglected diseases

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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