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Chemotherapy regimen more effective and more toxic in Japanese patients than in American patients

A chemotherapy regimen commonly used to treat non-small cell lung cancer is both more effective and more toxic in Japanese patients than in American patients, researchers reported Saturday at the annual meeting of the American Society of Clinical Oncologists.

7 Jun 2004

A biological agent used without chemotherapy appears to offer a disease-free future to patients with rare leukemia

A biological agent — a drug that wraps vitamin A inside bubbles of fat — used without chemotherapy appears to offer as many as one-third of patients with a rare form of leukemia an opportunity for a long-term, disease-free future, say researchers at The University of Texas M. D. Anderson Cancer Center.

7 Jun 2004

Experimental human monoclonal antibody shows striking benefit in patients with advanced melanoma

Early testing of an experimental human monoclonal antibody showed a striking benefit in patients with advanced melanoma, say researchers at The University of Texas M. D. Anderson Cancer Center, who presented their findings at the annual meeting of the American Society of Clinical Oncology.

7 Jun 2004

Investigational drug, LAF237 improved glycemic control in patients with type 2 diabetes

Research presented today showed that the investigational drug, LAF237, the first in a new class, improved glycemic control in patients with type 2 diabetes. In this study, LAF237, which is administered as a tablet to be taken orally, was added to the standard diabetes treatment metformin in patients whose diabetes was not adequately controlled by metformin alone.

7 Jun 2004

Combination treatment may help type 2 diabetes patients

New research presented by Peter Weissman, M.D., from the University of Miami, at the 64th Annual Scientific Sessions of the American Diabetes Association shows that combination treatment with rosiglitazone maleate and metformin significantly improves certain markers of cardiovascular disease risk in patients with type 2 diabetes compared to metformin alone.

6 Jun 2004

Velcade major improvement over standard therapy for relapsed multiple myeloma

Early results from a major, international Phase III clinical trial decisively show that recurrent multiple myeloma is more effectively treated with the drug bortezomib (trade name: Velcade TM) than with dexamethasone, a drug that for decades has been the standard therapy for relapsed disease, researchers at Dana-Farber Cancer Institute report.

6 Jun 2004

Overweight families unaware & unconcerned about risk of diabetes and premature heart disease

Two new studies show that many children are at high risk for diabetes and premature heart disease, according to British and U.S. reports here today at the American Diabetes Association's 64th Annual Scientific Sessions.

5 Jun 2004

Vitamin C can increase the severity of spontaneous knee osteoarthritis

High doses of vitamin C increase the severity of spontaneous knee osteoarthritis in an animal model of the disease, according to a new study by Duke University Medical Center researchers.

5 Jun 2004

Polycystic ovary syndrome more common than originally thought

Researchers at Cedars-Sinai Medical Center and the University of Alabama, Birmingham, have found that a complex hormonal disorder affecting the reproductive and metabolic function of premenopausal women may be considerably more common in the United States than previously believed from earlier, smaller studies.

5 Jun 2004

Parents oblivious to their children's weight problems

5 Jun 2004

Breakthrough in gene therapy

Despite a roller-coaster ride of ups and downs during the past 15 years, gene therapy has continued to attract many of the world's brightest scientists. They are tantalized by the enormous potential that replacing missing genes or disabling defective ones offers for curing diseases of many kinds.

3 Jun 2004

Chromium picolinate supplementation reduced carbohydrate cravings and atypical depression

Results of a new double-blind, placebo-controlled human clinical trial found that daily supplementation with chromium picolinate significantly reduced some key symptoms of atypical depression.

2 Jun 2004

Avastin study shows significant improvement in patients with metastatic colorectal cancer

Genentech, Inc. and Roche have announced that the New England Journal of Medicine published the first Phase III study of an anti-angiogenesis cancer therapy, showing that the addition of Avastin™ (bevacizumab) to the IFL chemotherapy regimen (5-FU/Leucovorin/ CPT-11) significantly extended survival in patients with first-line (previously untreated) metastatic colorectal cancer.

2 Jun 2004

New device enable physicians to quickly join blood vessels during heart bypass surgery

Guidant Corporation has announced that the company has begun distribution of Cardica Inc.’s C-Port™ Distal Anastomosis System in Europe. Cardica’s C-Port System, which recently received approval, is designed to enable physicians to quickly and easily join blood vessels during heart bypass surgery.

2 Jun 2004

Acne drug may help treat multiple sclerosis

Dr. Luanne Metz, an associate professor of neurosciences and physician-scientist in the Neuroscience Research Group at the University of Calgary’s Faculty of Medicine, has found that minocycline, a drug currently used to treat such conditions as acne, decreases the activity of lesions in the brains of people suffering from multiple sclerosis (MS).

2 Jun 2004

Chocolate is good for your heart

UCSF scientists are publishing sweet results of a study examining chocolate's effects on blood vessel function in healthy people. The team reports that small daily doses of flavonoid-rich dark chocolate consumed over a two-week period improved blood vessels' ability to dilate, or expand.

1 Jun 2004

Treatment helps 26% of black Americans with chronic hepatitis C

Twenty-six percent (26%) of black Americans (BA) with chronic hepatitis C who received treatment with Pegasys plus Copegus (peginterferon alfa-2a plus ribavirin) achieved a sustained virological response (SVR), according to study results published in the June 2004 issue of Hepatology.

1 Jun 2004

Clinical trial of 5 day treatment for earliest form of breast cancer

Researchers at Virginia Commonwealth University’s Massey Cancer Center have begun a clinical trial testing the effectiveness of an established balloon catheter radiation delivery device on the earliest form of breast cancer, ductal carcinoma in situ.

27 May 2004

More than half of Quebecers over 65 have no teeth

More than half of Quebecers over 65 have no teeth. This is a problem of major proportions, given that medical studies indicate that tooth loss has a negative impact on diet and health.

27 May 2004

ABIOMED has announced the 14th implantation of replacement heart

ABIOMED, Inc. today announced the 14th implantation of the AbioCor® Implantable Replacement Heart. The implant was performed on May 24 in Louisville, KY by a Jewish Hospital/University of Louisville medical team led by surgeons Laman Gray, M.D. and Rob Dowling, M.D. The procedure went well and without complication. The patient is recovering, and is in critical but stable condition.

27 May 2004

Clinical Trial News and Research

Chemotherapy regimen more effective and more toxic in Japanese patients than in American patients

A biological agent used without chemotherapy appears to offer a disease-free future to patients with rare leukemia

Experimental human monoclonal antibody shows striking benefit in patients with advanced melanoma

Investigational drug, LAF237 improved glycemic control in patients with type 2 diabetes

Combination treatment may help type 2 diabetes patients

Velcade major improvement over standard therapy for relapsed multiple myeloma

Overweight families unaware & unconcerned about risk of diabetes and premature heart disease

Vitamin C can increase the severity of spontaneous knee osteoarthritis

Polycystic ovary syndrome more common than originally thought

Parents oblivious to their children's weight problems

Breakthrough in gene therapy

Chromium picolinate supplementation reduced carbohydrate cravings and atypical depression

Avastin study shows significant improvement in patients with metastatic colorectal cancer

New device enable physicians to quickly join blood vessels during heart bypass surgery

Acne drug may help treat multiple sclerosis

Chocolate is good for your heart

Treatment helps 26% of black Americans with chronic hepatitis C

Clinical trial of 5 day treatment for earliest form of breast cancer

More than half of Quebecers over 65 have no teeth

ABIOMED has announced the 14th implantation of replacement heart

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