Clinical Trial News and Research

RSS

New study challenges current thinking about varied response to hepatitis C treatment in different racial groups

Results of a new study published in the current issue of the New England Journal of Medicine show that in patients who have chronic hepatitis C, genotype 1 -- the most common form of the disease and difficult to treat successfully -- non-Hispanic whites achieved one of the highest response rates reported to date, but response rates in African Americans were significantly lower.

27 May 2004

Human Genome Sciences has begun dosing patients with chronic hep C drug

Human Genome Sciences, Inc. announced today that it has begun dosing patients in a Phase 2 clinical trial of Albuferon™ (albumin-interferon alpha) in patients with chronic hepatitis C who are naïve to interferon-alpha treatments.

27 May 2004

New company is developing advanced therapeutics for stroke victims

Arizona Engineered Therapeutics Inc., a new company based on the research of three Arizona State University professors, is moving its first drug candidate closer to clinical trials.

26 May 2004

Focus on implantation of artificial discs to treat degenerative disc disease

Implantation of artificial discs to treat degenerative disc disease was the subject of multiple presentations earlier this month at the Spine Arthroplasty Meeting in Vienna, Austria, where spine and orthopaedic surgeons from all over the world heard new data about this technology.

25 May 2004

Zengen announces positive results of treatment for vaginal yeast infection

Zengen Inc. announced today positive phase I/II results for its proprietary molecule CZEN-002 for the treatment of vulvovaginal candidiasis (VVC), commonly known as vaginal yeast infection.

25 May 2004

CRT devices used in combination with optimized pharmacologic therapy (OPT) significantly impact patient's quality and length of life

UI Heart Care researchers are among the first in the nation to evaluate the effectiveness of cardiac resynchronization therapy (CRT) devices to reduce the risk of mortality and hospitalization in advanced heart failure patients.

25 May 2004

Launch of Zorbtive for use in the treatment of patients with short bowel syndrome

Serono, Inc., the US affiliate of Serono, announced today the launch of Zorbtive™ [somatropin (rDNA origin) for injection] for use in the treatment of patients with short bowel syndrome.

25 May 2004

X-ray beams could kick start genes into fighting cancer

X-ray beams could kick start genes into fighting cancer as an exciting new way of targeting therapy against the disease, according to new research in the Journal of Gene Medicine.

25 May 2004

Heart failure is a leading cause of death and nearly 5 million people in the United States suffer from it

“Heart failure is a leading cause of death and nearly 5 million people in the United States suffer from it,” says Mariell Jessup, MD, Professor of Medicine and Medical Director of the Heart Failure and Transplantation Program at the Hospital of the University of Pennsylvania (HUP).

24 May 2004

Trial shows Daclizumab therapy improves multiple sclerosis outcome

A small clinical trial of patients with multiple sclerosis (MS) who did not respond to interferon alone found that adding the human antibody daclizumab improved patient outcome. Patients who received the combined therapy had a 78 percent reduction in new brain lesions and a 70 percent reduction in total lesions, along with other significant clinical improvements.

24 May 2004

Significant symptom relief reported in clinical trial patients with irritable bowel syndrome

Solvay Pharmaceuticals unveiled this week results from a six-month study of both male and female patients and from a subgroup analysis of males with Irritable Bowel Syndrome with Diarrhea predominance (IBS-D).

24 May 2004

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

Researchers in the department of ophthalmology at the University of Arizona College of Medicine in Tucson played an important role in the development of Restasis, the first alternative to artificial tears for the treatment of dry eye syndrome.

21 May 2004

Pacemaker-type device and medicines reduce hospital stays and death rates

A nationwide clinical trial of more than 1,600 heart failure patients showed that when medicines are combined with the use of a pacemaker-type device that resynchronizes both sides of the heart, hospital stays and death rates drop significantly.

20 May 2004

Dietary supplement reduces body fat mass in overweight adults by as much as nine percent

A study to be published in the June issue of The American Journal of Clinical Nutrition concludes that the dietary supplement, conjugated linoleic acid (CLA), reduces body fat mass in overweight, but otherwise healthy, adults by as much as nine percent.

20 May 2004

Study has important implications for African Americans who suffer from high blood pressure

A new study has important implications for the millions of African Americans who suffer from high blood pressure. The study, AADVANCE, shows Diovan HCT(R) (valsartan and hydrochlorothiazide) lowers blood pressure in African Americans to aggressive recommended target blood pressure goals as effectively as amlodipine.

20 May 2004

CRT implantable defibrillators significantly reduce hospitalization rates and extend lives

Researchers at the University of Colorado Health Sciences Center have announced the findings of a large-scale clinical trial for patients with late-stage heart failure. Results showed that cardiac resynchronization therapy (CRT) from implantable pacemaker-like devices or CRT combined with an implantable defibrillator (CRT-D), when used in addition to optimal drug therapy, reduced significantly the mortality and first hospitalization rate when compared to drug therapy alone. CRT-D also substantially lowered mortality.

19 May 2004

$First drug approved for hormone refractory prostate cancer that has shown a survival benefit$

First drug approved for hormone refractory prostate cancer that has shown a survival benefit

The the Food and Drug Administration (FDA) approved Taxotere (docetaxel), injection in combination with prednisone ( a steroid), for the treatment of patients with advanced metastatic prostate cancer. This is the first drug approved for hormone refractory prostate cancer that has shown a survival benefit.

19 May 2004

Clinical trial of traditional Chinese medicine for the treatment of male infertility

Traditional Chinese Medicine (TCM) researcher Jann Mehmet knows the effectiveness of acupuncture and Chinese herbal medicine in treating male infertility. Now she is putting her observations to the test in a formal clinical trial of the benefits of TCM, the first time such a study has been conducted in Australia - or overseas.

18 May 2004

Study comparing the efficacy of REMICADE® to Azathioprine alone and in combination With REMICADE®

Centocor, Inc., and Schering-Plough Corporation announced today the initiation of the SONIC (Study of Immunomodulator Naive patients in Crohn's Disease) trial that will evaluate the efficacy of REMICADE® (infliximab) versus azathioprine, a conventional immunosuppressive agent, alone and versus the combination of both drugs for the treatment of patients with Crohn's disease.

18 May 2004

Discovery of the gene for Cornelia de Lange syndrome

An international team of researchers has discovered the gene for Cornelia de Lange syndrome, a disabling, multisystem genetic disease that affects an estimated one in 10,000 children. The finding is expected to lead to a genetic test, enabling rapid and definitive diagnosis of the syndrome, as well as prenatal testing for families who already have one child with the disease.

17 May 2004

Clinical Trial News and Research

New study challenges current thinking about varied response to hepatitis C treatment in different racial groups

Human Genome Sciences has begun dosing patients with chronic hep C drug

New company is developing advanced therapeutics for stroke victims

Focus on implantation of artificial discs to treat degenerative disc disease

Zengen announces positive results of treatment for vaginal yeast infection

CRT devices used in combination with optimized pharmacologic therapy (OPT) significantly impact patient's quality and length of life

Launch of Zorbtive for use in the treatment of patients with short bowel syndrome

X-ray beams could kick start genes into fighting cancer

Heart failure is a leading cause of death and nearly 5 million people in the United States suffer from it

Trial shows Daclizumab therapy improves multiple sclerosis outcome

Significant symptom relief reported in clinical trial patients with irritable bowel syndrome

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

Pacemaker-type device and medicines reduce hospital stays and death rates

Dietary supplement reduces body fat mass in overweight adults by as much as nine percent

Study has important implications for African Americans who suffer from high blood pressure

CRT implantable defibrillators significantly reduce hospitalization rates and extend lives

First drug approved for hormone refractory prostate cancer that has shown a survival benefit

Clinical trial of traditional Chinese medicine for the treatment of male infertility

Study comparing the efficacy of REMICADE® to Azathioprine alone and in combination With REMICADE®

Discovery of the gene for Cornelia de Lange syndrome

eBook: Using iPSCs models for human disease research and drug discovery eBook

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

Latest Life Science News