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New pan-cancer T cell atlas provides a deeper understanding of complex tumor microenvironment

A new study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, provides a deeper understanding of the vast diversity of T cell states as well as their relationships and roles within the complex tumor microenvironment, bringing a fresh perspective to understanding immunotherapy efficacy in cancer.

29 May 2023

Two key physiological systems found to be involved in high-salt-induced hypertension and dementia

Dementia is defined as the loss of cognitive functioning-;including thinking, remembering, and reasoning-;and is very prevalent in Japan.

29 May 2023

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

More than 40% of Americans are considered obese, and the trend continues to grow. The treatments or preventive options for obesity and obesity-associated diseases are limited.

26 May 2023

Researchers develop microrobotic system capable of rapid, targeted elimination of fungal pathogens

Infections caused by fungi, such as Candida albicans, pose a significant global health risk due to their resistance to existing treatments, so much so that the World Health Organization has highlighted this as a priority issue.

26 May 2023

Hydrogen sulfide can be used to support photothermal therapy for cancer

Hydrogen sulfide is usually a highly toxic gas. However, with careful preparation, it can be used to support photothermal therapy (PTT) in treating cancer, as a team of researchers reporting in the journal Angewandte Chemie has recently discovered.

26 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

Associations between exposure to air pollution and severe COVID-19

Researchers explored associations between prolonged exposure to air pollution and severe coronavirus disease 2019.

26 May 2023

Tumors in distant organs remotely reprogram the liver

Cancers often release molecules into the bloodstream that pathologically alter the liver, shifting it to an inflammatory state, causing fat buildup and impairing its normal detoxifying functions, according to a study from investigators at Weill Cornell Medicine.

25 May 2023

Biological abnormality makes some infants vulnerable to sudden death

Sudden infant death syndrome is a case where the death of an apparently healthy infant before their first birthday remains unexplained even after thorough investigation. Death generally seems to occur when infants are sleeping.

25 May 2023

New tool shows early promise to help reduce the spread of antimicrobial resistance

A new tool which could help reduce the spread of antimicrobial resistance is showing early promise, through exploiting a bacterial immune system as a gene editing tool.

25 May 2023

Statistical modeling based of Australian native possum excreta identifies locations of Buruli ulcer occurrence in humans

The study aimed to predict the future human Buruli ulcer case locations via statistical modelling.

25 May 2023

$Is prediabetes associated with increased fracture risk among midlife women?$

Is prediabetes associated with increased fracture risk among midlife women?

Studying the correlation between prediabetes before the menopause and increased fracture risk.

25 May 2023

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

In this behind-the-scenes interview, we speak to Dr. Sinead Knight, chair of SLAS Europe 2023, about this years programme, highlighting the key topics and speakers.

From Society for Laboratory Automation and Screening (SLAS) 25 May 2023

Researchers disclose how a nanomachine takes care of cleaning up inside the cell

To prevent our body's cells from overflowing with garbage and to keep them healthy, the waste inside them is constantly being disposed of.

25 May 2023

Study maps cellular responses to blood sugar

Researchers at The University of Texas at El Paso have successfully mapped specific regions in the brain that are activated in association with changes in blood sugar -; also known as glucose -; providing fundamental location information that could ultimately lead to more targeted therapies for people who struggle with conditions like diabetes.

25 May 2023

Berry beneficial: Blueberry consumption alleviates abdominal pain in gastrointestinal disorders

Researchers investigate whether blueberry consumption could improve the overall quality of life of individuals with functional gastrointestinal disorders.

24 May 2023

New class of tiny, self-propelled robots could one day deliver drugs throughout the human body

A team of engineers at the University of Colorado Boulder has designed a new class of tiny, self-propelled robots that can zip through liquid at incredible speeds-;and may one day even deliver prescription drugs to hard-to-reach places inside the human body.

24 May 2023

As water levels drop, the risk of arsenic poisoning rises

When John Mestas’ ancestors moved to Colorado over 100 years ago to raise sheep in the San Luis Valley, they “hit paradise,” he said.

24 May 2023

Cannabis use, emotions, and mental health: Unraveling the young adult connection

Emotion dysregulation mediates the association between cannabis use and mental health in young adults, with sex-dependent effects observed in female users. Interventions targeting emotion dysregulation are crucial for improving mental health outcomes in female, young adult cannabis users.

23 May 2023

New trial data validates a rapid diagnostic test for sepsis

Critical care physician Hollis O'Neal, MD, MSc, Associate Professor of Medicine at LSU Health New Orleans School of Medicine's Baton Rouge campus, presented data that validate a rapid diagnostic test for sepsis at the American Thoracic Society 2023 International Conference.

23 May 2023

Laboratory News and Research

New pan-cancer T cell atlas provides a deeper understanding of complex tumor microenvironment

Two key physiological systems found to be involved in high-salt-induced hypertension and dementia

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

Researchers develop microrobotic system capable of rapid, targeted elimination of fungal pathogens

Hydrogen sulfide can be used to support photothermal therapy for cancer

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Associations between exposure to air pollution and severe COVID-19

Tumors in distant organs remotely reprogram the liver

Biological abnormality makes some infants vulnerable to sudden death

New tool shows early promise to help reduce the spread of antimicrobial resistance

Statistical modeling based of Australian native possum excreta identifies locations of Buruli ulcer occurrence in humans

Is prediabetes associated with increased fracture risk among midlife women?

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

Researchers disclose how a nanomachine takes care of cleaning up inside the cell

Study maps cellular responses to blood sugar

Berry beneficial: Blueberry consumption alleviates abdominal pain in gastrointestinal disorders

New class of tiny, self-propelled robots could one day deliver drugs throughout the human body

As water levels drop, the risk of arsenic poisoning rises

Cannabis use, emotions, and mental health: Unraveling the young adult connection

New trial data validates a rapid diagnostic test for sepsis

Lab Diagnostics and Automation - Second Edition eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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