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International Committee of Medical Journal Editors updates requirements for clinical trials registry

The International Committee of Medical Journal Editors (ICMJE) today issued a follow-up joint editorial regarding its goal to foster a comprehensive, publicly available database of clinical trials. The joint editorial by 11 ICMJE member journals is published online simultaneously today and is posted on the JAMA website. It will also appear in print in the June 15 issue of JAMA.

23 May 2005

Within six months, one in three patients fail to take cardiovascular risk-lowering medications as prescribed

Therapy that includes medications to reduce high blood pressure and to lower lipid levels can reduce risk for heart disease, but within six months, more than a third of patients fail to take one or both medications as prescribed, according to a study in the May 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

23 May 2005

Obesity appears to increase the risk of prostate cancer

The obesity study examined the association between body mass index - weight to height ratio - and prostate cancer in 787 men undergoing biopsy due to an elevated tumor marker in the blood or an abnormal physical exam at a Veterans Affairs hospital in California between 1998 and 2002.

23 May 2005

Sarcasm the lowest form of wit demands the highest functions of the brain

New research suggests that the highest functions of our brains handle the lowest form of wit.

23 May 2005

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, UCSF medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences.

23 May 2005

Vietnam reports another bird flu death

A death of a man from bird flu in Vietnam's Northern Province, has brought the total deaths in the country since late 2003 to 38.

23 May 2005

Incretin hormones, a new wave of promising diabetes research

A new understanding of specialized incretin (or gut) hormones may lead to significant advances in the treatment and management of type 2 diabetes. This conclusion and other recent research were reported recently at the 14th Annual Meeting and Clinical Congress of the American Association for Clinical Endocrinologists (AACE) in Washington, DC.

23 May 2005

Minimally invasive procedure to treat varicose veins results in less swelling, bruising and minimal pain

The return of warm summer months can be a dreadful time for women who are embarrassed to wear shorts or short skirts due to unsightly, twisted and swollen varicose veins.

23 May 2005

Bone loss reduced by blocking body's cannabis-like substances

British scientists have discovered that blocking the action of cannabis-like substances produced naturally by the body can reduce bone loss and they hope this finding will lead to new drugs to treat osteoporosis and other bone diseases.

23 May 2005

Being married or in a relationship significantly improves quality of life for prostate cancer patients following treatment

Partnered men reported better psychosocial and spiritual well-being, suffered fewer adverse effects from treatment and had less fear and anxiety about their cancer coming back than did their single counterparts, the study found.

23 May 2005

Scientists show nuclear protein Ezh2 helps establish previously unknown signaling pathway in cells

Since 2001, scientists have wrestled with the discovery that there are fewer genes in humans than biological processes linked to those genes over the course of a human lifespan. One way to understand genetically coded events is by studying epigenetics, the regulation and heritability of genes at a cellular level due to molecular changes to the many proteins (called histones) that package DNA in a cell's nucleus.

23 May 2005

Pregnancy factors, parental psychiatric history, and preterm delivery may be associated with the risk of autism

...according to a recent study supported in part by the Centers for Disease Control and Prevention (CDC). The study, "Risk Factors for Autism: Perinatal Factors, Parental Psychiatric History, and Socioeconomic Status," appears in the most recent issue of the American Journal of Epidemiology.

23 May 2005

Guyana Health Minister outlines progress at World Health Assembly

Guyana Health Minister Dr. Leslie Ramsammy has outlined health progress being made in his country despite high levels of poverty and major floods that affected hundreds of thousands of people earlier this year.

23 May 2005

Gene keeps neural cells on correct developmental path

Embryonic stem cells with identical genomes grow into distinctive tissues, such as heart, bone, and brain. At one time, scientists believed the differences among cell types arose from various sets of genes switched on inside developing cells.

23 May 2005

Health Protection Agency publishes report on the benefits of vaccination to children's health

The Health Protection Agency today publishes its first national report on the current status of the UK’s universal vaccine programmes, which protect children against a range of childhood diseases including measles, mumps, rubella and meningitis.

23 May 2005

Findings demonstrate that abnormal expression of the BCL6 gene causes lymphoma

This advancement has the potential to significantly speed the development of new, improved therapies for diffuse large B cell lymphoma (DLBCL), the most common type of human B cell lymphoma. Human B cell lymphomas cause 85 percent of non-Hodgkin’s lymphomas, the sixth leading cause of cancer deaths in the United States.

23 May 2005

Celebrity UV Guide, using star skin types as a guide to when people should cover up

Britons are missing vital weather warnings that could help reduce their risk of skin cancer. New figures show more than 70% of people questioned in a special survey do not know what the UV Index is despite its frequent appearance on TV weather forecasts and websites.

23 May 2005

Sleeping time and obesity in children

Three-year-old children who spend more than eight hours watching television each week are at an increased risk of obesity as they grow up.

23 May 2005

Major step forward in stem cell research

Newcastle University (England) scientists have taken a major step forward in stem cell research, putting Britain in the vanguard of technology that could produce treatments for a range of conditions such as diabetes, Parkinson’s disease and spinal injuries.

23 May 2005

Market forces alone are not sufficient to produce new drugs needed for children with cancer

Faced with "a near absence of research in pediatric cancer drug discovery," the IOM report recommends forming new public-private partnerships among government, industry, researchers, advocacy groups and other parties to lead research and development.

23 May 2005

Research News and Research

International Committee of Medical Journal Editors updates requirements for clinical trials registry

Within six months, one in three patients fail to take cardiovascular risk-lowering medications as prescribed

Obesity appears to increase the risk of prostate cancer

Sarcasm the lowest form of wit demands the highest functions of the brain

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Vietnam reports another bird flu death

Incretin hormones, a new wave of promising diabetes research

Minimally invasive procedure to treat varicose veins results in less swelling, bruising and minimal pain

Bone loss reduced by blocking body's cannabis-like substances

Being married or in a relationship significantly improves quality of life for prostate cancer patients following treatment

Scientists show nuclear protein Ezh2 helps establish previously unknown signaling pathway in cells

Pregnancy factors, parental psychiatric history, and preterm delivery may be associated with the risk of autism

Guyana Health Minister outlines progress at World Health Assembly

Gene keeps neural cells on correct developmental path

Health Protection Agency publishes report on the benefits of vaccination to children's health

Findings demonstrate that abnormal expression of the BCL6 gene causes lymphoma

Celebrity UV Guide, using star skin types as a guide to when people should cover up

Sleeping time and obesity in children

Major step forward in stem cell research

Market forces alone are not sufficient to produce new drugs needed for children with cancer

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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