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Adaptive, light-activated nanotherapy effective against drug-resistant bacteria

In the ever-escalating evolutionary battle with drug-resistant bacteria, humans may soon have a leg up thanks to adaptive, light-activated nanotherapy developed by researchers at the University of Colorado Boulder.

19 Jan 2016

New discovery may help researchers tackle mitochondrial diseases and age-related diseases

Buck Institute faculty Judith Campisi, PhD, says age researchers need to stop thinking of cellular senescence, now accepted as an important driver of aging, as a single phenotype that stems from genotoxic stress. Research from her lab reveals that cellular senescence, a process whereby cells permanently lose the ability to divide, is also induced by signaling from dysfunctional mitochondria - and that the arrested cells secrete a distinctly different "stew" of biologically active factors in a process unrelated to the damaging free radicals that are created in mitochondria as part of oxygen metabolism.

13 Jan 2016

Estrogen may protect women against flu

The female sex hormone estrogen has anti-viral effects against the influenza A virus, commonly known as the flu, a new study in American Journal of Physiology—Lung Cellular and Molecular Physiology reports.

13 Jan 2016

Researchers use quick screening method to identify, test promising anti-Ebola drugs

A quick screening method has been used for the first time in a standard open laboratory to identify and test promising anti-Ebola drugs. This approach increases the possibility of finding new therapies faster.

12 Jan 2016

AiCure closes $12.25 million in Series A fundraising round

AiCure, an artificial intelligence company connecting the world's patients to better treatments and improved health, has closed a Series A fundraising round with $12.25 million. The consortium is led by New Leaf Venture Partners, with additional participation from Pritzker Group Venture Capital, Tribeca Venture Partners, and Biomatics Capital, established by Boris Nikolic, former Chief Advisor for Science and Technology to Bill Gates.

11 Jan 2016

New study finds significant racial disparity in patients with HIV and Hodgkin lymphoma

A new study finds a significant racial disparity within a doubly troubled population of patients: those with HIV and Hodgkin lymphoma. In such cases, blacks are at significantly higher risk than whites of not receiving treatment for the cancer that in many cases would be effective.

11 Jan 2016

Patient recommendations for rheumatoid arthritis treatment: an interview with Dr Nowell

The study, “When patients write the guidelines: Patient panel recommendations for the treatment of RA,” published in Arthritis Research & Care, demonstrated the feasibility of developing CPG recommendations based on a voting panel composed entirely of patients.

8 Jan 2016

ISHLT issues new list of criteria to determine patient eligibility for heart transplant

To determine patient eligibility for heart transplant, the International Society for Heart Lung Transplantation maintains a list of criteria, first issued in 2006, that acts as a guideline for physicians.

7 Jan 2016

Transgender veterans have significantly greater prevalence of many psychiatric and medical conditions

The first large, controlled study of health disparities between clinically diagnosed transgender and non-transgender patients-based on the medical records of more than 5,000 patients treated in the Veterans Health Administration-showed that transgender veterans had a significantly greater prevalence of numerous psychiatric and medical conditions.

7 Jan 2016

Modeling research shows adding a vaccine to HIV/AIDS response necessary to conclusively end the epidemic

Adding a vaccine to the comprehensive HIV/AIDS response is essential to conclusively ending the epidemic, according to modeling research published today.

6 Jan 2016

International panel of clinical experts comment on state of their fields

In an Editorial published this week in PLOS Medicine, editors ask an international panel of eleven expert researchers and clinicians spanning a range of specialties to answer questions on their field and what developments they hope and expect to see in 2016.

30 Dec 2015

Ebola virus and bats waging molecular battle for survival

Ebola virus and bats have been waging a molecular battle for survival that may have started at least 25 million years ago, according to a study led by researchers at Albert Einstein College of Medicine, the University of Colorado-Boulder (CU-Boulder) and the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) that published online today in the journal eLife.

24 Dec 2015

Single VRC01 antibody infusion could suppress HIV level in people not taking ART

A single infusion of a powerful antibody called VRC01 can suppress the level of HIV in the blood of infected people who are not taking antiretroviral therapy (ART), scientists at the National Institutes of Health report in a paper published today.

24 Dec 2015

Immunogeneticist helps monitor immune responses in VRC01 phase 1 trial in HIV-infected individuals

Janardan Pandey, Ph.D., an immunogeneticist specializing in immunoglobulin GM genes at the Medical University of South Carolina, helped monitor for immune responses that could limit the effectiveness of the broadly neutralizing antibody VRC01 in a phase 1 trial of that antibody in HIV-infected individuals led by a team at the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

24 Dec 2015

New footage shows how AIDS vaccine candidate recruits immune cells to destroy infected cells

Using innovative technology, scientists from the Institut Pasteur and Inserm have filmed in vivo the process by which an AIDS vaccine candidate, developed by the French Vaccine Research Institute and the ANRS, triggers the immune response.

23 Dec 2015

ATS commends President Obama for release of National Action Plan to combat TB

The American Thoracic Society applauds President Barack Obama and the Administration for the release of the National Action Plan to Combat Drug Resistant Tuberculosis (TB) today.

23 Dec 2015

FDA updates blood donor deferral recommendations to help ensure continued safety of blood supply

Today, the U.S. Food and Drug Administration issued final guidance outlining updated blood donor deferral recommendations to reflect the most current scientific evidence and to help ensure continued safety of the blood supply by reducing the risk of human immunodeficiency virus (HIV) transmission by blood and blood products.

22 Dec 2015

Targeted alpha therapy has potential to reduce HIV-infected cells from central nervous system

Targeted alpha therapy has the potential to selectively eliminate HIV infected cells from the central nervous system, according to a recent study co-authored by the JRC. The study shows that a specific human antibody labelled with the alpha emitter bismuth-213 can penetrate the blood brain barrier and selectively target and destroy HIV-infected cells while sparing non-infected healthy cells.

21 Dec 2015

Roche's cobas HIV-1 viral load test approved by FDA for use on cobas 6800 and cobas 8800 Systems

Roche announced today that it has received FDA approval for the cobas HIV-1 viral load test by the United States Food and Drug Administration for use on the cobas 6800 and cobas 8800 Systems. This HIV-1 viral load test is part of the next generation of Roche viral load tests, which clinicians use to manage the disease and treatment of patients infected with HIV-1.

21 Dec 2015

MPP signs licensing agreement with AbbVie to address future demands for HIV treatment in Africa

The Medicines Patent Pool today announced a new licensing agreement with AbbVie, a global biopharmaceutical company, that seeks to address future demands for HIV treatment Lopinavir/Ritonavir (LPV/r) in South Africa and across Africa. The agreement has been reached in particular to help ensure sustainability of long-term supply of LPV/r, the most widely used second-line HIV treatment in South Africa and across Africa.

18 Dec 2015

HIV 1 News and Research

Adaptive, light-activated nanotherapy effective against drug-resistant bacteria

New discovery may help researchers tackle mitochondrial diseases and age-related diseases

Estrogen may protect women against flu

Researchers use quick screening method to identify, test promising anti-Ebola drugs

AiCure closes $12.25 million in Series A fundraising round

New study finds significant racial disparity in patients with HIV and Hodgkin lymphoma

Patient recommendations for rheumatoid arthritis treatment: an interview with Dr Nowell

ISHLT issues new list of criteria to determine patient eligibility for heart transplant

Transgender veterans have significantly greater prevalence of many psychiatric and medical conditions

Modeling research shows adding a vaccine to HIV/AIDS response necessary to conclusively end the epidemic

International panel of clinical experts comment on state of their fields

Ebola virus and bats waging molecular battle for survival

Single VRC01 antibody infusion could suppress HIV level in people not taking ART

Immunogeneticist helps monitor immune responses in VRC01 phase 1 trial in HIV-infected individuals

New footage shows how AIDS vaccine candidate recruits immune cells to destroy infected cells

ATS commends President Obama for release of National Action Plan to combat TB

FDA updates blood donor deferral recommendations to help ensure continued safety of blood supply

Targeted alpha therapy has potential to reduce HIV-infected cells from central nervous system

Roche's cobas HIV-1 viral load test approved by FDA for use on cobas 6800 and cobas 8800 Systems

MPP signs licensing agreement with AbbVie to address future demands for HIV treatment in Africa

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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