Biopsy News and Research

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Biopsy is the removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. When a wide needle is used, the procedure is called a core biopsy. When a thin needle is used, the procedure is called a fine-needle aspiration biopsy.

Possible link between aggressive prostate cancer and vitamin D deficiency

Vitamin D deficiency was an indicator of aggressive prostate cancer and spread of the disease in European-American and African-American men who underwent their first prostate biopsy because of abnormal prostate-specific antigen (PSA) and/or digital rectal examination (DRE) test results, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

1 May 2014

Noninvasive technique detects prostate cancer using an electronic nose

We may soon be able to make easy and early diagnoses of prostate cancer by smell. Investigators in Finland have established that a novel noninvasive technique can detect prostate cancer using an electronic nose. In a proof of principle study, the eNose successfully discriminated between prostate cancer and benign prostatic hyperplasia (BPH) by "sniffing" urine headspace (the space directly above the urine sample). Results using the eNose are comparable to testing prostate specific antigen (PSA), reports the Journal of Urology.

1 May 2014

Enrichment of highly abundant epigenetic marks from endometrial stromal cells

Chromatrap®, the novel solid-based matrix for chromatin immunoprecipitation (ChIP) assays, available from Porvair Sciences, has been successfully used to isolate high quality chromatin from difficult biopsy material.

From Chromatrap® - Porvair Sciences Ltd 30 Apr 2014

Low baseline QOL scores does not predict worse survival in patients undergoing lung cancer surgery

Quality of life (QOL) is rarely reported in surgical publications, yet it can be an important metric that can be of use to physicians and patients when making treatment decisions.

30 Apr 2014

U of L School of Medicine researchers use breath analysis to detect lung cancer

Researchers at the University of Louisville School of Medicine are using breath analysis to detect the presence of lung cancer. Preliminary data indicate that this promising noninvasive tool offers the sensitivity of PET scanning, and has almost twice the specificity of PET for distinguishing patients with benign lung disease from those with early stage cancer.

30 Apr 2014

GE Healthcare announces commercial availability of new Alzheimer’s diagnostic tool

GE Healthcare today announced the first seven markets where Vizamyl (Flutemetamol F18 injection), a radioactive diagnostic agent approved by the FDA will be available. Late in the second quarter of 2014, Vizamyl will be available to imaging centers near East Rutherford, NJ, Woburn, MA, Beltsville, MD, East Lansing, MI, Dallas, TX, Phoenix, AZ and Colton, CA.

29 Apr 2014

Inflammation has ‘etiologic link’ with prostate cancer

Chronic inflammation of prostate tissue is strongly associated with subsequent development of prostate cancer, show results of a US observational study.

28 Apr 2014

Mauna Kea receives regulatory approval in Japan for Cellvizio flagship product

Mauna Kea Technologies, leader in the optical biopsy market, announced today it received regulatory approval in Japan for the company's Cellvizio flagship product.

28 Apr 2014

CrossBay Medical gets FDA clearance for SonoSure Sonohysterography and Endometrial Sampling Device

CrossBay Medical, Inc., today announced the United States Food and Drug Administration clearance of its product, the SonoSure Sonohysterography and Endometrial Sampling Device. The device has also received Health Canada clearance and the CE mark. The SonoSure is indicated for use to access the uterine cavity for saline infusion sonohysterography and to obtain endometrial biopsy, if indicated, utilizing the same device.

26 Apr 2014

Researchers use gold nanoparticles to detect, measure cancer levels in living cell

Purdue University researchers have developed a way to detect and measure cancer levels in a living cell by using tiny gold particles with tails of synthetic DNA.

25 Apr 2014

Aspirin can lower colon cancer risk among people with high levels of specific gene

The humble aspirin may have just added another beneficial effect beyond its ability to ameliorate headaches and reduce the risk of heart attacks: lowering colon cancer risk among people with high levels of a specific type of gene.

25 Apr 2014

Measuring tumors' oxygen levels could help doctors make decisions about treatments

Unlike healthy cells, cancer cells thrive when deprived of oxygen. Tumors in low-oxygen environments tend to be more resistant to therapy and spread more aggressively to other parts of the body.

25 Apr 2014

ASTRO’s guideline details use of adjuvant radiation therapy in treatment of endometrial cancer

The American Society for Radiation Oncology (ASTRO) has issued a new guideline, "The Role of Postoperative Radiation Therapy for Endometrial Cancer: An ASTRO Evidence-Based Guideline," that details the use of adjuvant radiation therapy in the treatment of endometrial cancer.

25 Apr 2014

Zenalux, RPCI collaborate to enhance Zenascope system to detect oral cancers at an early stage

Zenalux Biomedical, Inc., a leader in biophotonic diagnostics, is working with Roswell Park Cancer Institute to further enhance its flagship Zenascope™ product by adding a high-resolution camera to the system.

25 Apr 2014

Anxiety experienced with false-positive mammogram does not negatively impact woman's well-being

Dartmouth researchers have found that the anxiety experienced with a false-positive mammogram is temporary and does not negatively impact a woman's overall well-being. Their findings are reported in "Consequences of False-Positive Screening Mammograms," which was published online in the April 21, 2014 JAMA Internal Medicine.

23 Apr 2014

IMPAKT breast cancer conference abstracts online

Xenografts and mathematical modelling; liquid biopsy; nanotechnology; next generation genomics- Science is running fast and the impact of new technologies in the care of patients with breast cancer will be at the core of the sixth edition of the IMPAKT conference on translational research in breast cancer.

22 Apr 2014

Neoadjuvant targeted treatment shows feasibility for limited clear-cell RCC

Treating patients with nonmetastatic clear-cell renal cell carcinoma with the tyrosine kinase inhibitor axitinib could not only prevent disease progression, but also shrink tumours before surgery, show the results of a phase II trial.

22 Apr 2014

Sarepta Therapeutics plans to submit eteplirsen NDA for treatment of Duchenne muscular dystrophy

Sarepta Therapeutics, Inc., a developer of innovative RNA-based therapeutics, today announced it plans to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration by the end of 2014 for the approval of eteplirsen for the treatment of Duchenne muscular dystrophy (DMD).

21 Apr 2014

Researchers devise new approach to treatment of Alzheimer's disease

A team of researchers from Columbia University Medical Center, Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called retromer protein complex. Retromer plays a vital role in neurons, steering amyloid precursor protein (APP) away from a region of the cell where APP is cleaved, creating the potentially toxic byproduct amyloid-beta, which is thought to contribute to the development of Alzheimer's.

21 Apr 2014

Men with chronic inflammation in non-cancerous prostate tissue may have nearly twice risk of prostate cancer

Men who show signs of chronic inflammation in non-cancerous prostate tissue may have nearly twice the risk of actually having prostate cancer than those with no inflammation, according to results of a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.

18 Apr 2014

Biopsy News and Research

Further Reading

Possible link between aggressive prostate cancer and vitamin D deficiency

Noninvasive technique detects prostate cancer using an electronic nose

Enrichment of highly abundant epigenetic marks from endometrial stromal cells

Low baseline QOL scores does not predict worse survival in patients undergoing lung cancer surgery

U of L School of Medicine researchers use breath analysis to detect lung cancer

GE Healthcare announces commercial availability of new Alzheimer’s diagnostic tool

Inflammation has ‘etiologic link’ with prostate cancer

Mauna Kea receives regulatory approval in Japan for Cellvizio flagship product

CrossBay Medical gets FDA clearance for SonoSure Sonohysterography and Endometrial Sampling Device

Researchers use gold nanoparticles to detect, measure cancer levels in living cell

Aspirin can lower colon cancer risk among people with high levels of specific gene

Measuring tumors' oxygen levels could help doctors make decisions about treatments

ASTRO’s guideline details use of adjuvant radiation therapy in treatment of endometrial cancer

Zenalux, RPCI collaborate to enhance Zenascope system to detect oral cancers at an early stage

Anxiety experienced with false-positive mammogram does not negatively impact woman's well-being

IMPAKT breast cancer conference abstracts online

Neoadjuvant targeted treatment shows feasibility for limited clear-cell RCC

Sarepta Therapeutics plans to submit eteplirsen NDA for treatment of Duchenne muscular dystrophy

Researchers devise new approach to treatment of Alzheimer's disease

Men with chronic inflammation in non-cancerous prostate tissue may have nearly twice risk of prostate cancer

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