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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Recently discovered protein holds potential for the development of new tests for infectious diseases

In a first for the genetic toolset known as CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA, single-stranded DNA and double-stranded DNA.

4 Jan 2023

Structure and function of a newly discovered CRISPR immune system revealed

In a rare feat, Utah State University biochemists Thomson Hallmark and Ryan Jackson, along with collaborators, published not one, but two seminal papers in a top-tier, peer-reviewed journal this week.

4 Jan 2023

Distinct genomic patterns of malignant peripheral nerve sheath tumors may help with early diagnosis

Neurofibromatosis type 1 (NF1) is a common genetic condition, affecting 1 in 3000 individuals, and people with NF1 are at greater risk of developing a rare, aggressive form of cancer.

4 Jan 2023

New type of CRISPR gene scissors discovered

Like humans, bacteria and archaea can be attacked by viruses. These microorganisms have developed their own immune defense strategies against their pathogens.

4 Jan 2023

Study shows the clinical utility of amniotic fluid cells RNA-sequencing in prenatal rare disease diagnosis

A clinical research team from the Department of Paediatrics and Adolescent Medicine and the Department of Obstetrics and Gynaecology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) leads the discovery of applying amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis to help more families with tailored clinical management.

4 Jan 2023

The relationship between metabolic disease and alternations in lipid homeostasis

Researchers assessed the function of lipids in metabolic diseases.

4 Jan 2023

Keeping hydrated can reduce aging and extend disease-free life

In a recent study published in the journal eBioMedicine, researchers assessed the association between hydration and aging.

3 Jan 2023

Researchers discover new role of small RNAs in Salmonella infections

Salmonella are food-borne pathogens that infect millions of people a year. To do so, these bacteria depend on a complex network of genes and gene products that allow them to sense environmental conditions.

3 Jan 2023

Researchers identify novel gene mechanism in most aggressive kidney cancers

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway with loss of the tuberous sclerosis complex (TSC) tumor suppressor gene.

3 Jan 2023

'Epigenetic fingerprints' of prenatal alcohol exposure could be biomarkers to detect developmental disorders

Alcohol exposure in early pregnancy can change gene function during the tightly regulated embryonic development, and consequently cause developmental disorders - especially neurodevelopmental disorders.

3 Jan 2023

Deep learning tool identifies mosaic mutations that cause disease

Genetic mutations cause hundreds of unsolved and untreatable disorders. Among them, DNA mutations in a small percentage of cells, called mosaic mutations, are extremely difficult to detect because they exist in a tiny percentage of the cells.

2 Jan 2023

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23, entitled, "DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife."

30 Dec 2022

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

Lung cancer is the leading cause of death in Japan and across the globe. Among all the cancers, lung cancer has one of the lowest five-year survival rates.

28 Dec 2022

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine.

28 Dec 2022

AI can improve the effectiveness of colonoscopy in the presence of Lynch syndrome

First study of AI-assisted colonoscopy for colorectal cancer surveillance in patients with genetic predisposition - People with Lynch syndrome have a higher hereditary risk of colon cancer.

28 Dec 2022

Scientists explore synthesis of griffithsin in cell-free systems

A new study described the cell-free manufacturing of griffithsin (GRFT), a broad-spectrum antiviral protein.

28 Dec 2022

Virus-only diet can fuel the physiological and population growth of an organism

Over a single day, in the placid waters of a single pond, a million virus particles might enter a single-celled organism known for the minuscule hairs, or cilia, that propel it through those waters.

27 Dec 2022

Researchers discover a protein linked with the onset of anthracycline-associated cardiac toxicity

Anthracyclines are a class of chemotherapies effective in treating many forms of cancer, including leukemias, lymphomas and breast cancer.

27 Dec 2022

Xanthan gum-based fluid thickener can lower blood glucose levels after eating, study shows

Type 2 diabetes mellitus is a common lifestyle disease that is prevalent worldwide. It can often lead to complications, such as diseases of the heart, and increased risk of death, but preventive measures, such as a healthy diet, can reduce these risks.

27 Dec 2022

New software accurately infers continental ancestry from tumor DNA and RNA

Could knowing where your ancestors came from be the key to better cancer treatments? Maybe, but where would that key fit? How can we trace cancer's ancestral roots to modern-day solutions?

27 Dec 2022

DNA News and Research

Further Reading

Recently discovered protein holds potential for the development of new tests for infectious diseases

Structure and function of a newly discovered CRISPR immune system revealed

Distinct genomic patterns of malignant peripheral nerve sheath tumors may help with early diagnosis

New type of CRISPR gene scissors discovered

Study shows the clinical utility of amniotic fluid cells RNA-sequencing in prenatal rare disease diagnosis

The relationship between metabolic disease and alternations in lipid homeostasis

Keeping hydrated can reduce aging and extend disease-free life

Researchers discover new role of small RNAs in Salmonella infections

Researchers identify novel gene mechanism in most aggressive kidney cancers

'Epigenetic fingerprints' of prenatal alcohol exposure could be biomarkers to detect developmental disorders

Deep learning tool identifies mosaic mutations that cause disease

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

AI can improve the effectiveness of colonoscopy in the presence of Lynch syndrome

Scientists explore synthesis of griffithsin in cell-free systems

Virus-only diet can fuel the physiological and population growth of an organism

Researchers discover a protein linked with the onset of anthracycline-associated cardiac toxicity

Xanthan gum-based fluid thickener can lower blood glucose levels after eating, study shows

New software accurately infers continental ancestry from tumor DNA and RNA

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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