Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

International project to develop globally accessible bank of new cancer cell models for research

An international project to develop a large, globally accessible bank of new cancer cell culture models for the research community launched today.

12 Jul 2016

ANTRUK awards first research contract to Evotec to find ways of breaking antibiotic resistance

Thanks to the generosity of its donors, Antibiotic Research UK – the world’s first charity established to fight antibiotic resistance, provide patient support and raise awareness of the issue of antibiotic resistance – has awarded its first research contract to Evotec, a leading organisation in drug discovery and development.

11 Jul 2016

Deadly bacteria can travel to the brain and spinal cord in 24 hours, new study finds

A deadly bacteria that can be picked up by a simple sniff can travel to the brain and spinal cord in just 24 hours, a new Griffith University and Bond University study has found.

11 Jul 2016

Minoryx Therapeutics initiates phase 1 clinical trial of MIN-102

Minoryx Therapeutics, a drug development company specialized in the discovery and development of new drugs for orphan diseases, today announces the initiation of its first-in-man Phase 1 clinical trial for its lead compound MIN-102.

7 Jul 2016

New research highlights need to abandon modern hygiene hypothesis

The July issue of Perspectives in Public Health (published by the Royal Society of Public Health) takes an objective view of ongoing research showing that the hygiene hypothesis – the idea that allergies are the price we are paying for our “modern obsession with cleanliness” – is a misleading misnomer.

6 Jul 2016

BioTek Instruments expands in Canada

BioTek Instruments, Inc. affirms their ongoing investment across the North American microplate-based technology market with the expansion of their business in Canada. The dedicated sales and support operation will focus on bringing enhanced applications and technical support throughout the country.

6 Jul 2016

Alnylam reports new results from investigational RNAi therapeutic programs

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today preliminary results from its ongoing Phase 2 open-label extension (OLE) studies with patisiran and revusiran, both investigational RNAi therapeutics targeting transthyretin (TTR) for the treatment of hereditary TTR-mediated amyloidosis (hATTR amyloidosis).

6 Jul 2016

ESCMID-ASM conference aims to speed up drug development processes for drug-resistant infections

The European Society of Clinical Microbiology and Infectious Diseases and the American Society for Microbiology (ASM) are jointly organizing a conference in Vienna from 21 – 23 September 2016 to help researchers accelerate the development of new antimicrobials for drug-resistant infections.

27 Jun 2016

Re-engineering cardiac scarring process could improve clinical outcomes for heart disease patients

Literal heartbreak, from illness or injury, triggers the body's natural healing mechanisms.

25 Jun 2016

Insilico Medicine collaborates with Asia Genomics to develop advanced personalized longevity suite

Insilico Medicine Inc, a big data analytics company located at the Emerging Technology Centers at the Johns Hopkins University at Eastern, announced an agreement with Asia Genomics, a Singapore-based rapidly growing molecular diagnostics company specializing in clinical genomics & genetic testing operating in major Asian countries including Vietnam, Malaysia and China.

22 Jun 2016

Molecular map of transporter proteins could be vital step toward drug discovery against zinc-related diseases

Mapping the molecular structure where medicine goes to work is a crucial step toward drug discovery against deadly diseases.

21 Jun 2016

Rice University researchers synthesize new anti-cancer agent

Rice University scientists have synthesized a novel anti-cancer agent, Thailanstatin A, which was originally isolated from a bacterial species collected in Thailand.

20 Jun 2016

New collaborative research program connects canine and human cancers

A new collaborative research program pairs oncologists who treat childhood and adult sarcomas with veterinarians who manage the same cancers in canine patients.

17 Jun 2016

New research paves way for potential notch-based anticancer therapeutics

A recent study led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, in collaboration with the Univerity of Maryland School of Pharmacy and StemSynergy Therapeutics, Inc., has identified a small-molecule inhibitor of the Notch pathway, paving the way for a potential new class of personalized cancer medicines.

16 Jun 2016

Prospective biobank studies with genetic data can help improve drug development, reduce costs

With drug development costs topping $1.2bn (£850 million) to get a single treatment to the point it can be sold and used in the clinic, could genetic analysis save hundreds of millions of dollars?

15 Jun 2016

Life Extension, Insilico Medicine team up to identify novel biomarkers of human aging

Life Extension (use different web link to highlight our technical attributes), a Florida-based organization established in the early 1980s is dedicated to extending healthy human longevity.

8 Jun 2016

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

A drug, more commonly used in the treatment of angina, could be the focus of a new strategy in fighting the fatal fungal infection cryptococcosis

8 Jun 2016

RapifleX MALDI PharmaPlus Solution for uHTS launched by Bruker

At the 64th ASMS Conference, Bruker announces the launch of the new rapifleX™ MALDI PharmaPulse™ (MPP) solution. It is the latest addition to Bruker’s portfolio of innovative products designed to assist pharmaceutical, biotech and CRO customers to accelerate drug discovery, and rapifleX MPP can dramatically lower the cost of ultra-high throughput screening (uHTS) with further improved results.

From Bruker Life Sciences Mass Spectrometry 7 Jun 2016

New systems-based strategy may help accelerate TB drug discovery

The rise in multi-drug resistant (MDR) and extremely drug resistant (XDR) strains of Mycobacterium tuberculosis (MTB) is becoming a major cause of global health concern for treating tuberculosis, which affects a third of the global population.

7 Jun 2016

Innovative mouse model could provide new strategy to arrest growth of pancreatic cancer

Pancreatic ductal adenocarcinoma, the most common of pancreatic cancers, is extraordinarily lethal, with a 5-year survival rate of just 6 percent. Chemotherapy treatments are poorly effective, in part due to a high degree of drug-resistance to currently used regimens.

7 Jun 2016

Drug Discovery News and Research

Further Reading

International project to develop globally accessible bank of new cancer cell models for research

ANTRUK awards first research contract to Evotec to find ways of breaking antibiotic resistance

Deadly bacteria can travel to the brain and spinal cord in 24 hours, new study finds

Minoryx Therapeutics initiates phase 1 clinical trial of MIN-102

New research highlights need to abandon modern hygiene hypothesis

BioTek Instruments expands in Canada

Alnylam reports new results from investigational RNAi therapeutic programs

ESCMID-ASM conference aims to speed up drug development processes for drug-resistant infections

Re-engineering cardiac scarring process could improve clinical outcomes for heart disease patients

Insilico Medicine collaborates with Asia Genomics to develop advanced personalized longevity suite

Molecular map of transporter proteins could be vital step toward drug discovery against zinc-related diseases

Rice University researchers synthesize new anti-cancer agent

New collaborative research program connects canine and human cancers

New research paves way for potential notch-based anticancer therapeutics

Prospective biobank studies with genetic data can help improve drug development, reduce costs

Life Extension, Insilico Medicine team up to identify novel biomarkers of human aging

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

RapifleX MALDI PharmaPlus Solution for uHTS launched by Bruker

New systems-based strategy may help accelerate TB drug discovery

Innovative mouse model could provide new strategy to arrest growth of pancreatic cancer

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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