Transplant News and Research

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Study highlights potential of stem cells derived from adults in regenerative medicine

Donor age does not appear to influence the functionality of stem cells derived from adult body tissues, concludes a new review. The analysis of research on induced pluripotent stem cells (iPSCs) finds that not only are typical signs of aging reversed in iPSCs, but cells derived from both older and younger donors show the same ability to differentiate into mature body cells.

24 Apr 2018

Adipose-derived mesenchymal stem cells combined with fibrin matrix influences restoration of motor functions

The research team used model spinal cord injuries in rats for their purposes. As a result, it was found out that therapy by adipose-derived mesenchymal stem cells combined with fibrin matrix influences the restoration of motor functions.

24 Apr 2018

Podcast: KHN’s ‘What the Health?’ Nothing in health care ever goes away

Congressional Republicans have struck a decidedly different tone when talking about the Affordable Care Act, and the Democrats have introduced a new Medicare expansion bill.

20 Apr 2018

Brief bedside visual art intervention reduces pain, anxiety in cancer patients

A brief bedside visual art intervention (BVAI) facilitated by art educators improved mood and reduced pain and anxiety in a study of inpatients with haematological cancers.

19 Apr 2018

Teen patient gets a new lease on life

At just 18 years old, Megan Gagliardi was told she might die from a rare genetic heart condition. Now, thanks in part to UAB Medicine's Comprehensive Transplant Institute (CTI), she is celebrating her recent engagement and an important six-year anniversary -; all as the University of Alabama at Birmingham celebrates 50 years of transplant success.

19 Apr 2018

Study: Transplanted livers have a protective effect and reduce potential for organ rejection

Transplanted livers change the profile of blood cells in the recipients, reducing the potential for organ rejection, Mayo Clinic research shows.

18 Apr 2018

Single FMT enema produces sustained and significant improvements in cognitive function

A single treatment using an optimized, targeted form of faecal microbiota transplantation (FMT) produces sustained clinical and cognitive improvements, according to the results of a long-term follow-up of patients with liver cirrhosis and hepatic encephalopathy (HE) who had participated in a short-term study.

16 Apr 2018

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

Patients with hepatocellular carcinoma (HCC) waiting for a liver transplant in the USA are now significantly less likely to receive a new liver than they were around a decade ago. A nationwide study presented today at The International Liver Congress™ 2018 in Paris, France, has confirmed that patients with HCC on the liver transplant list in the USA were more than 50% less likely to receive a transplant in 2014-2016 than they were in 2005-2007.

13 Apr 2018

'Molecular microscope' system for transplant biopsy more effective than conventional methods

A transplant biopsy system that uses gene chips to read molecules is far safer and more effective than existing approaches used for heart transplant biopsies and is showing promising results for lung transplant biopsies, new University of Alberta-led research shows.

13 Apr 2018

HEV infections can be fatal and transmitted through blood products in immunosuppressed patients

Hepatitis E virus infection is once again in the spotlight, with two studies presented today at The International Liver Congress 2018 in Paris, France challenging the ideas that HEV infections are benign and self-limiting, and that blood-borne transmission is a rare event.

12 Apr 2018

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Kandice Fogle, 43, had just moved to Houston when she began experiencing pain in her back and groin. After undergoing a CT scan, doctors found a large mass in her liver. A biopsy confirmed that she had intrahepatic cholangiocarcinoma, more commonly known as bile duct cancer.

11 Apr 2018

Research identifies link between rare gene variants and survival after blood and marrow transplant

Blood and marrow transplant, or BMT, is a lifesaving and effective treatment for many patients, but the procedure can cause serious and life-threatening complications.

10 Apr 2018

Data-driven tool defines risk stages for children with chronic kidney disease

Experts in pediatric kidney disease have published a new staging system to help doctors better predict the length of time until a child with chronic kidney disease (CKD) will need to undergo a kidney transplant or start receiving dialysis. Although this type of prognostic guide exists for adults, this is the first such tool specific to children.

10 Apr 2018

New system promises greater accuracy in determining heart transplant rejection and injury

The results of an international clinical trial for a new system of diagnosing heart transplant rejection and injury will be presented publicly for the first time at the International Society for Heart & Lung Transplantation annual meeting, which will take place on April 11 and 12 in Nice, France.

10 Apr 2018

Using Cord Blood to Alleviate the Symptoms of Autism

Cord blood has been studied extensively for the treatment of hematological diseases such as cancer and sickle cell anemia, but is now in phase II trials for the alleviation of autism. Dr. Ann Smith, director of Smart Cells who provided the cord blood for the trial, discusses the research and it's potential.

9 Apr 2018

Analysis reveals decreasing trend in infection-related mortality among kidney transplant recipients

Since the 1990s, the risk of dying from infections after kidney transplantation has dropped by half, according to a recent analysis. The analysis, which appears in an upcoming issue of the Clinical Journal of the American Society of Nephrology, also found that common bacterial infections remain the most frequent cause of infection-related death among transplant recipients.

6 Apr 2018

Bob and Corrine Frick's gift helps establish first center for heart failure and arrhythmia

The Ohio State University Wexner Medical Center will establish the nation's first center dedicated to treating those with heart failure and arrhythmia with gifts totaling $18 million from Bob and Corrine Frick.

5 Apr 2018

Microscopic revelations could lead to new treatment options for deadly blood infections

Researchers at the University of Calgary's Cumming School of Medicine (CSM) have for the first time been able to observe -- live and in real-time -- how the human body responds to often lethal fungal blood infections in the lung.

4 Apr 2018

MIT researchers develop new portable device to monitor white blood cell levels

One of the major side effects of chemotherapy is a sharp drop in white blood cells, which leaves patients vulnerable to dangerous infections. MIT researchers have now developed a portable device that could be used to monitor patients' white blood cell levels at home, without taking blood samples.

3 Apr 2018

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients with blood cancers such as leukemia. In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.

3 Apr 2018

Transplant News and Research

Study highlights potential of stem cells derived from adults in regenerative medicine

Adipose-derived mesenchymal stem cells combined with fibrin matrix influences restoration of motor functions

Podcast: KHN’s ‘What the Health?’ Nothing in health care ever goes away

Brief bedside visual art intervention reduces pain, anxiety in cancer patients

Teen patient gets a new lease on life

Study: Transplanted livers have a protective effect and reduce potential for organ rejection

Single FMT enema produces sustained and significant improvements in cognitive function

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

'Molecular microscope' system for transplant biopsy more effective than conventional methods

HEV infections can be fatal and transmitted through blood products in immunosuppressed patients

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Research identifies link between rare gene variants and survival after blood and marrow transplant

Data-driven tool defines risk stages for children with chronic kidney disease

New system promises greater accuracy in determining heart transplant rejection and injury

Using Cord Blood to Alleviate the Symptoms of Autism

Analysis reveals decreasing trend in infection-related mortality among kidney transplant recipients

Bob and Corrine Frick's gift helps establish first center for heart failure and arrhythmia

Microscopic revelations could lead to new treatment options for deadly blood infections

MIT researchers develop new portable device to monitor white blood cell levels

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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