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South Africa launches HIV/AIDS vaccine trial

"The first clinical trial of an HIV/AIDS vaccine designed and developed in South Africa was launched in Cape Town" Monday, the SAPA/The Times reports.

20 Jul 2009

Cost of health care reform emerges as ‘lightning rod’ issue

The cost of health care reform has emerged as a key battle in overhaul efforts. Attention is being paid to how costs will affect specific groups including the middle class and businesses.

16 Jul 2009

Sunitinib shows promise for advanced kidney cancer patients with poor prognosis

Sunitinib prolongs progression-free and overall survival, and is safe and well tolerated in advanced kidney cancer (metastatic renal cell carcinoma) patients with a poor prognosis such as the elderly and those whose cancer has spread to the brain, finds an Article published Online First (www.thelancet.com) and in the August edition of The Lancet Oncology.

16 Jul 2009

Turmeric spice and vitamin D may help clear amyloid plaques found in Alzheimer's

UCLA scientists and colleagues from UC Riverside and the Human BioMolecular Research Institute have found that a form of vitamin D, together with a chemical found in turmeric spice called curcumin, may help stimulate the immune system to clear the brain of amyloid beta, which forms the plaques considered the hallmark of Alzheimer's disease.

15 Jul 2009

Schering-Plough expands Vicriviroc study in treatment-naive patients with HIV

Schering-Plough Corporation has announced that it has extended to stage two an ongoing Phase II clinical study with vicriviroc, its investigational CCR5 antagonist, for use in first-line therapy of adult treatment-naive HIV-infected patients with R5-type virus only. In this study, vicriviroc is being evaluated in a novel nucleoside-sparing regimen that is designed to provide additional options for treatment-naive patients in a once daily regimen, while preserving other drug classes for subsequent lines of treatment.

15 Jul 2009

WHO recommends vaccine makers move forward in mass production of H1N1 vaccine

"Saying the new H1N1 [swine flu] virus is 'unstoppable', the WHO gave drug makers a full go-ahead to manufacture vaccines against the pandemic influenza strain on Monday and said healthcare workers should be the first to get one," Reuters reports (Fox, 7/14).

15 Jul 2009

Why oral contraceptives fail for obese women

Researchers have identified a potential biological mechanism that could explain why oral contraceptives may be less effective at preventing pregnancy in obese women, as some epidemiological studies have indicated.

14 Jul 2009

Ethicists urge inclusion of pregnant women in Federal child-health study

A team of ethicists from Johns Hopkins, Duke and Georgetown universities is urging organizers of a recently begun $3 billion decades-long study of children's health to immediately add provisions to look at the health and medical profiles of the children's mothers during their pregnancies.

9 Jul 2009

Thiarabine shows promise for rheumatoid arthritis

Access Pharmaceuticals, Inc. announced today new preclinical data demonstrating that thiarabine shows remarkable efficacy in the prevention and treatment of rheumatoid arthritis (RA).

7 Jul 2009

Multaq approved for atrial fibrillation by FDA

Sanofi-aventis announced today that the U.S. Food and Drug Administration (FDA) has approved Multaq (dronedarone) 400 mg Tablets. Patients with atrial fibrillation (AF) or atrial flutter (AFL) soon will have a new treatment option to help improve current management of their disease. Multaq is the first drug approved in the United States that has shown a clinical benefit to reduce cardiovascular hospitalization in patients with AF/AFL.

7 Jul 2009

PATRICIA trial shows HPV vaccine effective in prevention of cervical lesions

The final analysis of the PATRICIA study shows that the HPV-16/18 AS04-adjuvanted vaccine (GlaxoSmithKline) has high efficacy against the precancerous cervical lesions that can eventually lead to cervical cancer.

6 Jul 2009

Golimumab shows promise for rheumatoid arthritis

Golimumab, a new tumour necrosis factor-α (TNF-α) inhibitor reduces the signs and symptoms of rheumatoid arthritis in patients who have previously received any other TNF-α inhibitor, and might be a good option for patients who have inadequate responses to one or two other TNF-α inhibitors, finds an Article published Online first and in this week's edition of The Lancet.

28 Jun 2009

Nanofountain-probe-based high-resolution patterning and single-cell injection of functionalized nanodiamonds

A research team at Northwestern University has developed a tool that can precisely deliver tiny doses of drug-carrying nanomaterials to individual cells.

28 Jun 2009

Nanoparticle-mediated targeting of MAPK signaling predisposes tumor to chemotherapy

An interdisciplinary team of researchers at Brigham and Women's Hospital and the Harvard-Massachusetts Institute of Technology (MIT) Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors.

28 Jun 2009

Blood pressure cuff could help improve the success of kidney transplants

The first clinical trial funded by the new Efficacy and Mechanism Evaluation (EME) programme will investigate whether a simple procedure to activate one of the body's natural defence mechanisms improves the function of kidneys after transplantation. This research is funded by the Medical Research Council and managed by the National Institute for Health Research.

25 Jun 2009

Music therapy for heart and stroke patients

Blood flow and respiratory rates can synch with music, indicating that music could one day be a therapeutic tool for blood pressure control and rehabilitation, according to a study by Italian researchers published in Circulation: Journal of the American Heart Association.

23 Jun 2009

Breakthrough in MR-guided, non-invasive neurosurgery

The Magnetic Resonance Center of the University Children's Hospital Zurich has achieved a world first break through in MR-guided, non-invasive neurosurgery. Ten patients have been successfully treated by means of transcranial high-intensity focused ultrasound. This fully non-invasive procedure opens new horizons for neurosurgery and the treatment of different neurological brain disorders.

23 Jun 2009

Seattle Genetics starts trial of SGN-35 for anaplastic large cell lymphoma

Seattle Genetics, Inc. (NASDAQ:SGEN), has announced that it has initiated a phase II clinical trial of SGN-35 for patients with relapsed or refractory systemic anaplastic large cell lymphoma (ALCL). SGN-35 is an antibody-drug conjugate (ADC) that utilizes Seattle Genetics’ proprietary technology to empower antibodies by linking them to potent cell-killing drugs.

18 Jun 2009

Pneumococcal vaccine effective in preventing severe pneumonia

A new trial has found that pneumococcal vaccine is effective in preventing severe pneumonia, the leading cause of death among children in developing countries. Co-ordinated by the National Institute for Health and Welfare (THL) between 2000 and 2004, a large scale efficacy trial - first of its kind in Asia - was carried out in the Philippines to investigate the effect of an investigational pneumococcal vaccine.

16 Jun 2009

Agencies and health departments prepare for swine flu

Governments and drug companies are struggling with efforts to prepare for a possible resurgence of swine flu in the fall as well as questioning who should receive swine flu vaccines as they ramp up production.

15 Jun 2009