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Preventing metabolic exhaustion in immune cells could enhance effects of immunotherapy

If you're an immune cell gearing up to fight cancer, you'd better eat your breakfast. The tumor microenvironment is a harsh place, and tumor cells are ready to wear you out.

6 Mar 2018

Johns Hopkins doctors successfully transplant hepatitis C-infected kidneys into virus-free patients

In a small study, doctors at Johns Hopkins have successfully transplanted 10 hepatitis C-infected kidneys into patients without hepatitis C and prevented the patients from becoming infected by hepatitis C. The success of these transplants could mean more organs being available for the nearly 100,000 people in the U.S. currently waiting for a kidney transplant.

6 Mar 2018

Restoring lipid synthesis could slow progression of pulmonary fibrosis

Pulmonary fibrosis, an ongoing process of scarring that leaves patients chronically short of breath, can progress in severity until the only course of treatment is lung transplant.

6 Mar 2018

Text messaging may hold promise in helping ALD liver-transplant patients maintain sobriety

Each year in the U.S., more than 40,000 patients need a liver transplant because of complications associated with cirrhosis and liver failure. Alcohol-related liver disease (ALD) alone accounts for nearly 30 percent of all liver transplants, yet up to 50 percent of patients with alcoholism return to drinking within five years of undergoing a liver transplant.

5 Mar 2018

Study reveals negative effect of hemodialysis on the brain of elderly patients

A new study reveals that hemodialysis may reduce blood flow to the brain in older patients being treated for kidney failure.

2 Mar 2018

Prediabetes linked to substantial risk for cardiovascular and chronic kidney diseases

Researchers at the Emory Rollins School of Public Health and U.S. Centers for Disease Control and Prevention have found that high proportions of patients with prediabetes are at substantial risk for cardiovascular disease and chronic kidney disease. Their findings are published in The Lancet Diabetes & Endocrinology.

2 Mar 2018

Leading consultants from the North East putting rare diseases expertise on world stage

This Rare Disease Day (28 February), the Academic Health Science Network, is shining a spotlight on the region’s healthcare pioneers chosen to lead three major European rare disease networks.

1 Mar 2018

Unique progenitor cells in the pancreas have potential to develop glucose-responsive beta cells

Scientists from the Diabetes Research Institute at the University of Miami Miller School of Medicine have confirmed the existence of progenitor cells within the human pancreas that can be stimulated to develop into glucose-responsive beta cells.

28 Feb 2018

Telomere length testing can alter treatment decisions for certain diseases

Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure.

27 Feb 2018

Research opens up new avenue to minimize risks of transplants

A bone marrow transplant is often the only therapy available to save leukemia patients, but the risk of complications is high. In spite of devoting considerable time and effort to finding a suitable donor, nearly half of all patients experience an unwanted reaction of their immune system, which often attacks their skin and liver and in up to 50% of cases the intestines.

21 Feb 2018

Study reveals HCT as effective treatment for NHL patients regardless of age

Results from a retrospective study of 1,629 patients with non-Hodgkin lymphoma showed that survival at 4 years following allogeneic hematopoietic cell transplantation for patients age 65 years and older is comparable to patients age 55 to 64 years.

21 Feb 2018

Computerized tissue-imaging may help predict early recurrence of lung cancer

Case Western Reserve and Cleveland Clinic are leading development of a computerized tissue-imaging program that could soon help identify which lung cancer patients are likely to face an earlier recurrence of the disease.

20 Feb 2018

Blood or marrow transplantation survivors have higher risk of cognitive impairment

Allogeneic blood or marrow transplantation recipients are at a significantly higher risk of cognitive impairment in the years post-transplantation, according to a study published in Journal of Clinical Oncology.

20 Feb 2018

New study to test safety, efficacy of MRI-guided focused ultrasound to treat Parkinson's disease

University of Maryland Medicine is leading a phase 3 study to test the safety and efficacy of using MRI-guided focused ultrasound on the brain in order to treat Parkinson's disease.

13 Feb 2018

Multi-spectral imaging shows promise for improving uterine transplant surgery

Future Science Group today announced the publication of an article in Future Science OA demonstrating the first use of multispectral imaging in gynecology, in a uterine transplant setting.

12 Feb 2018

Outcomes have improved for alternatives to whole liver transplants in children, study finds

In a new Johns Hopkins study of patient and graft survival trends for pediatric liver transplant recipients between 2002 and 2015, researchers found that outcomes for alternatives to whole liver transplantation, such as splitting a liver for two recipients or using a part of a liver from a living donor, have improved significantly.

8 Feb 2018

Study finds new stem cell pathway that allows triple-negative breast cancer to thrive

Cleveland Clinic researchers have published findings in Nature Communications on a new stem cell pathway that allows a highly aggressive form of breast cancer - triple-negative breast cancer - to thrive.

8 Feb 2018

Novel genetic mutations may explain link between high HDL cholesterol and reduced heart disease risk

Researchers at the University of Maryland School of Medicine have uncovered genetic mutations that may explain why people with high levels of high-density lipoprotein (HDL) cholesterol, the "good cholesterol," have a reduced risk of coronary heart disease.

7 Feb 2018

CHLA participates in clinical trial using stem cells to treat rare congenital heart defect

Children's Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare congenital heart defect that leaves them with half a heart.

5 Feb 2018

VUMC reaches new record in performing heart transplants

Vanderbilt University Medical Center performed a record number of heart transplants in 2017, surpassing the 2016 milestone and securing its place as the second-busiest heart transplant program in the country.

5 Feb 2018

Transplant News and Research

Preventing metabolic exhaustion in immune cells could enhance effects of immunotherapy

Johns Hopkins doctors successfully transplant hepatitis C-infected kidneys into virus-free patients

Restoring lipid synthesis could slow progression of pulmonary fibrosis

Text messaging may hold promise in helping ALD liver-transplant patients maintain sobriety

Study reveals negative effect of hemodialysis on the brain of elderly patients

Prediabetes linked to substantial risk for cardiovascular and chronic kidney diseases

Leading consultants from the North East putting rare diseases expertise on world stage

Unique progenitor cells in the pancreas have potential to develop glucose-responsive beta cells

Telomere length testing can alter treatment decisions for certain diseases

Research opens up new avenue to minimize risks of transplants

Study reveals HCT as effective treatment for NHL patients regardless of age

Computerized tissue-imaging may help predict early recurrence of lung cancer

Blood or marrow transplantation survivors have higher risk of cognitive impairment

New study to test safety, efficacy of MRI-guided focused ultrasound to treat Parkinson's disease

Multi-spectral imaging shows promise for improving uterine transplant surgery

Outcomes have improved for alternatives to whole liver transplants in children, study finds

Study finds new stem cell pathway that allows triple-negative breast cancer to thrive

Novel genetic mutations may explain link between high HDL cholesterol and reduced heart disease risk

CHLA participates in clinical trial using stem cells to treat rare congenital heart defect

VUMC reaches new record in performing heart transplants

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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