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Fatty acid pathway, glucose produce triacetic acid lactone

Scientists at the University of Illinois at Urbana-Champaign have designed a potential roadmap to use a biosynthetic pathway taken from a common microorganism to produce compounds that could serve as precursors to explosives or components in everyday devices such as liquid crystal displays or anti-cancer agents.

1 Apr 2004

Link Between Stress And Multiple Sclerosis Attacks

A new study that combined results of previously published research findings suggests that acute attacks of multiple sclerosis may be associated with stressful life events. The study, appearing in the British Medical Journal and funded in part through National MS Society postdoctoral fellowships, is a “meta-analysis” (which statistically combines findings) of previously published studies of the topic of stress and MS.

1 Apr 2004

Compounds that may stop replication of T-cell leukemia virus

Researchers are analyzing several compounds that may inhibit the enzyme that is essential for the reproduction of the Human T-cell Leukemia Virus Type 1 (HTLV-I), which has infected 15 to 20 million people worldwide. The virus causes the fatal adult T-cell leukemia in up to 10 percent of those infected.

1 Apr 2004

Whites and African-American pain thresholds most likely the same

Previous research and anecdotal clinical evidence have suggested that African-Americans tend to be more sensitive to pain than Whites, but the latest research study shows the two groups simply interpret standard pain rating scales differently. The new study also confirms earlier findings that women are more sensitive to pain than men.

1 Apr 2004

Machine can switch off brain by transmitting harmless magnetic pulses

Professor Snyder's creativity machine was developed at the Centre for the Mind, a joint venture between The Australian National University and the University of Sydney. The machine transmits harmless magnetic pulses through the brain, temporarily switching part of it off, with the potential to reveal an inner genius

1 Apr 2004

Scientists have discovered that a non-genetic molecular process can effect cell behaviour

Genetic mutations, sudden, random and usually harmful changes to the structure of a gene, are only one factor that determines the ultimate fate of a cell. Chicago scientists have discovered that a non-genetic molecular process also can play a role, and that experimenters can influence this process in bacteria, they report in the April 1 issue of the journal Nature.

1 Apr 2004

Research shows no association between whooping cough vaccine and asthma

Parents who may be concerned by a scare over the side effects of the whooping cough vaccine will be reassured by a new study involving thousands of children. The Department of Health advice that babies should be vaccinated against whooping cough (pertussis) at the age of two, three and four months has been questioned by some scientists who have suggested a link with asthma and allergies.

1 Apr 2004

Innovation that could help sufferers of Raynaud's Phenomenon

A student will display his "smart gloves" as part of the University of Dundee's annual exhibition of honours and research projects for students of Electronic and Electrical Engineering, Physics and Mechanical Engineering on Wednesday 31st March.

31 Mar 2004

Sheffield University pioneers osteoporosis research

A leading osteoporosis expert from Sheffield has been awarded the prestigious Society for Endocrinology Medal and the Kohn Foundation Award for his 25-year commitment to revolutionising the treatment and diagnosis of osteoporosis.

31 Mar 2004

Oxford Biomedica to win Department of Health gene funding

Oxford spinout Oxford Biomedica was yesterday awarded £0.5 million by the Department of Health to conduct the first British gene therapy haemophilia trial.

31 Mar 2004

How rat's genetic blueprint stacks up against those of mice and humans

An international research team, supported by the National Institutes of Health (NIH), today announced it has completed a high-quality, draft sequence of the genome of the laboratory rat, and has used that data to explore how the rat's genetic blueprint stacks up against those of mice and humans.

31 Mar 2004

SARS virus vaccine stimulates protective immune response

An experimental vaccine prevents the SARS virus from replicating in laboratory mice, according to a new report in the April 1 issue of Nature. Scientists at the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health, developed the vaccine. The vaccine was tested in a mouse model of SARS infection recently validated by other NIAID investigators.

31 Mar 2004

DakoCytomation has acquired exclusive worldwide rights to develop and commercialize pharmacogenomic diagnostic tests in the field of oncology

Human Genome Sciences, Inc. announced today a license agreement with DakoCytomation A/S (Glostrup, Denmark), under which DakoCytomation has acquired exclusive worldwide rights to develop and commercialize pharmacogenomic diagnostic tests in the field of oncology based on the TRAIL Receptor-1 (TRAIL-R1) and TRAIL Receptor-2 (TRAIL-R2) proteins.

31 Mar 2004

GlaxoSmithKline and Theravance to form strategic alliance

GlaxoSmithKline plc (GSK) and Theravance, Inc., a privately-held pharmaceutical company, announced today that they have entered into an innovative broad-based strategic alliance to develop and commercialise novel medicines across a variety of important therapeutic areas, including bacterial infection, respiratory, urinary incontinence and gastrointestinal.

31 Mar 2004

Gene-rich human Chromosome 19 sequence completed

The United States Department of Energy (DOE) Joint Genome Institute (JGI) and Stanford University report today the completion of the sequencing of human chromosome 19, the most gene-rich of all the human chromosomes.

31 Mar 2004

Scientists seek cause for what makes good cell go bad

Genetic mutations--sudden, random and usually harmful changes to the structure of a gene--are only one factor that determines the ultimate fate of a cell. Chicago scientists have discovered that a non-genetic molecular process also can play a role, and that experimenters can influence this process in bacteria, they report in the April 1 issue of the journal Nature.

31 Mar 2004

Research team has found a new way to streamline gene isolation to determine their functions

A single strand of plant or animal DNA may contain tens of thousands of genes, each programmed to produce a specific protein essential for the growth or survival of the organism. The challenge for geneticists is to isolate individual genes and determine their function -- a painstaking process often requiring years of laboratory trial and error.

31 Mar 2004

Heart disease can be reduced substantially by regularly treating existing gum infections

Reinforcing the relationship between periodontal disease and heart disease, oral biologists from the University at Buffalo have shown that levels of two inflammatory proteins known to raise the risk of heart disease can be reduced substantially by regularly treating existing gum infections.

31 Mar 2004

GenVec malaria vaccine initiative and the U.S. Naval Medical Research Center has announced partnership for malaria vaccine

GenVec, Inc., PATH's Malaria Vaccine Initiative (MVI), and the U.S. Naval Medical Research Center (NMRC) today announced a dynamic partnership to assess whether five malaria antigens, or proteins, can generate strong immune responses alone or in combination. This partnership will advance and expand the ongoing malaria vaccine development program between GenVec and NMRC. Malaria is one of the world's three leading infectious disease killers.

31 Mar 2004

Drug, Nembutal can suppress activity in colon cancer cells

A barbiturate once commonly used to treat anxiety may play a role in controlling the spread of colon cancer, say researchers from The University of Texas M. D. Anderson Cancer Center.

30 Mar 2004