DNA News and Research

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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Natural selection has played an important role in patterning the human genome

The most detailed analysis to date of how humans differ from one another at the DNA level shows strong evidence that natural selection has shaped the recent evolution of our species, according to researchers from Cornell University, Celera Genomics and Celera Diagnostics.

23 Oct 2005

Scientists discover molecular structure related to cell growth and cancer

Researchers discovered a special type of molecular structure that helps keep genes properly turned off until the structure is ejected from those genes in a regulated manner to help turn the genes on.

23 Oct 2005

Gene found only in men is altered by a chemical process, which is in turn linked to aggressive forms of melanoma

New scientific evidence that may shed light on why men are more likely than women to develop aggressive forms of skin cancer has been published in Carcinogenesis.

23 Oct 2005

Discovery of a new kind of messenger RNA molecule

Researchers at Cold Spring Harbor Laboratory have discovered a new kind of messenger RNA molecule that is converted from non-protein coding status to protein coding status in response to cellular stress such as viral infection.

20 Oct 2005

Spliceosome crucial for processing non-coding RNA

The discovery in 1977 that the coding regions of a gene could appear in separate segments along the DNA won the 1993 Nobel Prize in Physiology or Medicine for Richard J. Roberts and Phillip A. Sharp. The active segments of a gene were termed exons, separated from each other within the gene by inactive introns.

20 Oct 2005

"Junk" DNA not important to an organism's evolutionary survival

Genetic material derisively called "junk" DNA because it does not contain the instructions for protein-coding genes and appears to have little or no function is actually critically important to an organism's evolutionary survival, according to a study conducted by a biologist at the University of California, San Diego.

19 Oct 2005

Identification of a single chromosome region linked to specific language impairment

Researchers at the University of Toronto (U of T), Capital Health's Stollery Children's Hospital in Edmonton, Toronto's Hospital for Sick Children and their international collaborators have discovered a genetic abnormality that causes a type of language impairment in children

19 Oct 2005

A DNA-based vaccine could be a potent weapon against bird flu

Researchers scrambling to combat a virulent form of bird flu that could mutate into a form easily spread among humans should consider developing vaccines based on DNA, according to British biochemical engineers.

19 Oct 2005

Access to genetic counseling and testing are an important part of cancer control

Ten years after the identification of the first breast cancer susceptibility genes so few high-risk minority women have received genetic counseling or testing that the standard methods of calculating risk have not been validated in these groups and the results of genetic testing can still produce surprises.

18 Oct 2005

Newly discovered role of MECP2 gene in Rett Syndrome

Huda Zoghbi, of Baylor College of Medicine and the Howard Hughes Medical Institute and Juan Young, also of Baylor and colleagues report in the online Early Edition of the Proceedings of the National Academy of Science, posted the week of October 17, 2005, that the Rett Syndrome gene, MECP2, regulates RNA splicing.

18 Oct 2005

Hormone responsible for types of high blood pressure could also cause preeclampsia

Researchers at the University of Cincinnati (UC) Academic Health Center have found evidence of a hormone they say is responsible for certain types of high blood pressure (hypertension), and could also cause preeclampsia, a potentially dangerous condition that occurs during pregnancy.

17 Oct 2005

Men who smoke cigarettes may experience a significant decline in their capacity to father a child

Sperm from nearly two-thirds of the chronic smokers in the study failed a special test that measures the ability of sperm to fertilize an egg. On average, those men showed a 75 percent decline in fertilizing capacity when compared to nonsmokers. Lead researcher Loni Burkman, Ph.D., presented the results today (Oct. 17, 2005) at the American Society of Reproductive Medicine annual meeting in Montreal, Quebec.

17 Oct 2005

New genetic discovery may help explain why some people develop high blood pressure and others don't

It also gives new insight into how the kidneys govern the balance of salt in the body, a crucial task for regulating blood pressure. And, it reveals how a gene already linked to behavior and mental health can play a role in the body, as well as the brain.

17 Oct 2005

Significant step forward in the genome era

In what promises to be a significant step forward in the genome era, the National Human Genome Research Institute (NHGRI) today announced plans to devote a portion of its large-scale sequencing capacity to efforts aimed at identifying the genetic roots of specific diseases that have long eluded gene hunters.

17 Oct 2005

WWOX gene finding could lead to a new strategy for treating lung cancer

The research focused on a gene known as WWOX, which is lost or silenced in a large majority of lung cancers, and in cancers of the breast, ovary, prostate, bladder, esophagus and pancreas. The work was led by scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

17 Oct 2005

Tourette syndrome linked to SLITRK1 gene

Tourette syndrome is a distressing condition which affects one in every 100 people.

17 Oct 2005

Possible explanation for the higher incidence of lung cancer in African Americans

Faulty cell cycle "checkpoints" that fail to respond to DNA damage effectively may contribute to the high incidence of lung cancer in African-Americans, say researchers at Georgetown University's Lombardi Comprehensive Cancer Center and the National Cancer Institute (NCI).

16 Oct 2005

Cervical cancer vaccine shows promising results but smear tests still vital

Hopes of an end to routine smear testing have been raised by promising results achieved by a prototype cervical cancer vaccine.

16 Oct 2005

Discovery of agent that can suppress cancer development

In a case of basic science detective work, researchers at The University of Texas M. D. Anderson Cancer Center have solved the puzzle of the "inconsistent biomarker" and, in the process, may have discovered an agent that can suppress cancer development.

13 Oct 2005

PCBs found widely in the environment and absorbed in the diet - may damage sperm

Research by an European Union-supported international team of scientists has shown that polychlorinated biphenyls (PCBs) - synthetic organic chemicals found widely in the environment and absorbed in the diet - may damage sperm.

13 Oct 2005

DNA News and Research

Further Reading

Natural selection has played an important role in patterning the human genome

Scientists discover molecular structure related to cell growth and cancer

Gene found only in men is altered by a chemical process, which is in turn linked to aggressive forms of melanoma

Discovery of a new kind of messenger RNA molecule

Spliceosome crucial for processing non-coding RNA

"Junk" DNA not important to an organism's evolutionary survival

Identification of a single chromosome region linked to specific language impairment

A DNA-based vaccine could be a potent weapon against bird flu

Access to genetic counseling and testing are an important part of cancer control

Newly discovered role of MECP2 gene in Rett Syndrome

Hormone responsible for types of high blood pressure could also cause preeclampsia

Men who smoke cigarettes may experience a significant decline in their capacity to father a child

New genetic discovery may help explain why some people develop high blood pressure and others don't

Significant step forward in the genome era

WWOX gene finding could lead to a new strategy for treating lung cancer

Tourette syndrome linked to SLITRK1 gene

Possible explanation for the higher incidence of lung cancer in African Americans

Cervical cancer vaccine shows promising results but smear tests still vital

Discovery of agent that can suppress cancer development

PCBs found widely in the environment and absorbed in the diet - may damage sperm

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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