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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

Mutations of BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 people respectively, significantly increase the risk of certain cancers such as ovarian, breast, pancreatic and prostate cancer.

28 Nov 2022

Two studies emphasize the need for ethnically diverse prostate cancer genetic testing

More than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the disease remain unexplored for the majority of patients around the world.

28 Nov 2022

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Addressing this gap in research, a recent Nature Medicine study hypothesized that 4R isoform-specific MTBR-tau species accumulate in the patient’s brain of specific subtypes of 4R tauopathies.

28 Nov 2022

Common chemotherapy drug could carry toxic inheritance for future generations of cancer survivors

A common chemotherapy drug could carry a toxic inheritance for children and grandchildren of adolescent cancer survivors, Washington State University-led research indicates.

28 Nov 2022

Researchers discover a new function of CRISPR/Cas9 gene scissors

For several years now, the CRISPR/Cas9 gene scissors have been causing a sensation in science and medicine.

25 Nov 2022

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

24 Nov 2022

AI helps design synthetic DNA that controls cells' protein production

With the help of an AI, researchers at Chalmers University of Technology, Sweden, have succeeded in designing synthetic DNA that controls the cells' protein production.

24 Nov 2022

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

Exploring synthetic engineering of bacteriophages

In a new study, researchers demonstrated biological bacteriophage containment and synthetic engineering.

24 Nov 2022

Unexplored NGS data could help elucidate carcinogenesis and discover biomarkers

A new research perspective was published in Oncotarget's Volume 13 on November 17, 2022, entitled, "Treasures from trash in cancer research."

24 Nov 2022

MYC proteins form hollow spheres that shield the genome of cancer cells

MYC genes and their proteins play a central role in the emergence and development of almost all cancers. They drive the uncontrolled growth and altered metabolism of tumour cells. And they help tumours hide from the immune system.

23 Nov 2022

Study reveals structural insights into the elusive tankyrase protein that fuels bowel cancer

Scientists have revealed the inner workings of a key protein involved in a wide range of cellular processes – potentially paving the way for better and less toxic cancer drugs.

23 Nov 2022

Genome sequencing reveals a common ancestor for about 600 seemingly disparate fungi

About 600 seemingly disparate fungi that never quite found a fit along the fungal family tree have been shown to have a common ancestor, according to a University of Alberta-led research team that used genome sequencing to give these peculiar creatures their own classification home.

23 Nov 2022

New research could be the first step in better targeting breast cancer treatment

Researchers have identified a protein that, when present in high amounts in breast cancer tumors, is an indicator of whether DNA-damaging therapies will work or not.

23 Nov 2022

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

BGI has currently published over 440 SCI (Science Citation Index) papers in the field of cancer research, with a cumulative impact factor of over 4,000 points.

From BGI Genomics 23 Nov 2022

Study shows no undetected monkeypox virus transmission before May 2022 in Rotterdam and Amsterdam

Researchers investigated whether undetected human monkeypox virus transmission occurred before Rotterdam and Amsterdam's first documented monkeypox cases.

23 Nov 2022

Fungi detected in 35 cancer types, often intracellular

In a recent article published in the journal Cell, researchers found fungal deoxyribonucleic acid (DNA) and cells at low abundances across many human cancers, with cancer type-dependent variations in fungus community composition and fungal-bacteriome interactions.

22 Nov 2022

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

Gene therapies can treat, even potentially cure, certain genetic diseases, but it is challenging to deliver the treatments to the parts of the body where they are needed.

22 Nov 2022

Unique resource for identifying new biomarkers of environmental exposures in early life

Researchers now have a unique resource for identifying new biomarkers of environmental exposures in early life and understanding their health effects.

22 Nov 2022

Study investigates spread of Klebsiella superbug between humans and the environment

An international team of scientists investigating transmission of a deadly drug-resistant bacteria that rivals MRSA, has found that whilst the bugs are found in livestock, pets and the wider environment, they are rarely transmitted to humans through this route.

22 Nov 2022

DNA News and Research

Further Reading

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

Two studies emphasize the need for ethnically diverse prostate cancer genetic testing

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Common chemotherapy drug could carry toxic inheritance for future generations of cancer survivors

Researchers discover a new function of CRISPR/Cas9 gene scissors

New CRISPR-based tool can snip out faulty genes and replace them with new ones

AI helps design synthetic DNA that controls cells' protein production

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

Exploring synthetic engineering of bacteriophages

Unexplored NGS data could help elucidate carcinogenesis and discover biomarkers

MYC proteins form hollow spheres that shield the genome of cancer cells

Study reveals structural insights into the elusive tankyrase protein that fuels bowel cancer

Genome sequencing reveals a common ancestor for about 600 seemingly disparate fungi

New research could be the first step in better targeting breast cancer treatment

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

Study shows no undetected monkeypox virus transmission before May 2022 in Rotterdam and Amsterdam

Fungi detected in 35 cancer types, often intracellular

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

Unique resource for identifying new biomarkers of environmental exposures in early life

Study investigates spread of Klebsiella superbug between humans and the environment

eBook: A guide to RNA sequencing eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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