Immune System News and Research

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Formula may be right for infants, but experts warn that toddlers don’t need it

Formulas for toddlers are a burgeoning business in the United States: Sales of the drinks more than doubled in recent years as companies convinced parents that their little ones needed the liquid boost.

21 Sep 2022

Discovery of novel pathway offers a potential solution for preventing cancer chemo-resistance

Researchers have uncovered a novel pathway that explains how cancer cells become resistant to chemotherapies, which in turn offers a potential solution for preventing chemo-resistance.

20 Sep 2022

Tumors generate unique, temporary cell-in-cell structures to evade immunotherapy

Scientists have shown how tumour cells evade immunotherapy by generating unique, temporary cell-in-cell structures, where the inner cells remain in tact and can return to single tumour cells.

20 Sep 2022

UTHSC-led researchers receive $5.2 million to study obesity-mediated cancer risk

The National Cancer Institute has awarded more than $5.2 million to a team lead by researchers from the University of Tennessee Health Science Center for a study that will fill critical gaps in knowledge around obesity-mediated cancer risk.

20 Sep 2022

Humanized zebrafish could aid in the search for MS drugs

The zebrafish should be known to many aquarium enthusiasts mainly because of its striking pigmentation. However, the characteristic black-blue stripes, to which the animal owes its name, only form over time.

20 Sep 2022

BU investigator wins highly competitive awards to study the role of proteases in regulation of cellular defenses

Mohsan Saeed, PhD, assistant professor of biochemistry at Boston University School of Medicine (BUSM), has received a five-year, $2 million R35 grant from the National Institute of General Medical Sciences, as well as a five-year, $2.5 million R01 grant from the National Institute of Allergy and Infectious Diseases.

20 Sep 2022

Link between type 2 diabetes and UTIs explained

Lower immunity and recurring infections are common in type 1 and type 2 diabetes. Researchers at Karolinska Institutet in Sweden now show that the immune system of people with diabetes has lower levels of the antimicrobial peptide psoriasin, which compromises the urinary bladder's cell barrier, increasing the risk of urinary tract infection.

20 Sep 2022

Clearing pollution helps clear the fog of aging — and may cut the risk of dementia

During the past decade, a growing body of research has shown that air pollution harms older adults' brains, contributing to cognitive decline and dementia. What hasn't been clear is whether improving air quality would benefit brain health.

20 Sep 2022

Rheumatoid arthritis drug can reduce the risk of deterioration in myasthenia gravis

Early intervention with rituximab, a drug used in the treatment of rheumatoid arthritis (RA), can reduce the risk of deterioration in myasthenia gravis, an autoimmune disease that causes loss of muscle control.

19 Sep 2022

Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

Immune checkpoint inhibitor (ICI) therapy is a type of treatment for melanoma, the deadliest form of skin cancer, which blocks proteins on tumor or immune cells that prevent the immune system from killing cancer cells.

19 Sep 2022

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

If a secretion in the lungs’ alveoli is not cleared regularly, breathing difficulties can develop. In a study published in Science Immunology, a team led by Alexander Mildner and Achim Leutz has now explained the pivotal role of the transcription factor C/EBPb in this process.

16 Sep 2022

Lab experiments add further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19's viral pathogenesis -; a theory that was posited two years ago by a team of researchers at the Department of Energy's Oak Ridge National Laboratory.

16 Sep 2022

Mortality risk higher among children with primary immunodeficiency diseases infected with SARS-CoV-2

Children with certain immunodeficiency diseases carry mutations in genes that regulate the body's immune system against viral infections and they have a higher mortality rate due to COVID-19.

16 Sep 2022

Itchy eczema in children finally gets relief

This is the first large-scale, randomized, placebo-controlled trial of a monoclonal antibody in any skin disease, including eczema, in children as young as six months. The study, which included 31 sites in Europe and North America, was published in The Lancet.

16 Sep 2022

Higher levels of microbiota engraftment linked to greater chances of transplantation success

From incurable intestinal infections to metabolic syndrome, from melanoma, to chronic inflammatory bowel disease, such as irritable bowel syndrome, to Tourette's syndrome: many diseases can potentially be cured by Fecal Microbiota Transplantation (FMT), and researchers from the Catholic University, Rome and the University of Trento have shown that the greater the level of engraftment of the transplanted microorganisms, the greater the chances of success of the therapy.

15 Sep 2022

Immune System News and Research

Formula may be right for infants, but experts warn that toddlers don’t need it

Discovery of novel pathway offers a potential solution for preventing cancer chemo-resistance

Tumors generate unique, temporary cell-in-cell structures to evade immunotherapy

UTHSC-led researchers receive $5.2 million to study obesity-mediated cancer risk

Humanized zebrafish could aid in the search for MS drugs

BU investigator wins highly competitive awards to study the role of proteases in regulation of cellular defenses

Link between type 2 diabetes and UTIs explained

Clearing pollution helps clear the fog of aging — and may cut the risk of dementia

Rheumatoid arthritis drug can reduce the risk of deterioration in myasthenia gravis

Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

Lab experiments add further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis

Mortality risk higher among children with primary immunodeficiency diseases infected with SARS-CoV-2

Itchy eczema in children finally gets relief

Higher levels of microbiota engraftment linked to greater chances of transplantation success

Moral values determine COVID vaccination acceptance rates in the United States

New mechanism may prevent the natural aging of immune cells

Disruption of actin cytoskeleton is key to triggering human immune response, research finds

New immunotherapy approach may lead to an effective treatment for fibrosis

COVID-19 vaccine safety concerns result in lower vaccination rates among pregnant individuals in the United States

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